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1990 | 41 | 1-3 |

Tytuł artykułu

Effects of intra-amygdaloid TRH injections on motor activity and dominant-submissive behavior in rats competing for water

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
Puciłowski O., Trzaskowska E., Jankowska E., Kostowski W., Kupryszewski G.: Effects of intra-amygdaloid TRH injections on motor activity and dominant-submissive behavior in rats competing for water. Acta Physiol. Pol. 1990, 41(1-3); 71-77. The effect of thyrotropin releasing hormone (TRH) microinjections into the central amygdala (10 g in 0.5 1 into each side) on locomotor activity, water intake and dominance behavior in a water competition test was investigated in male Wistar rats. TRH increased the general motility without altering the number of rearings. Intra-amygdaloid TRH injection to submissive rats resulted in a loss ol subordinate position in these animals in the water competition test. A tendency to decrease dominance followed the injection оf the peptide to the dominant animals. The effect of TRH in the dominance test does not appear to involve influence on the thirst drive as microinjection of the peptide did not change significantly the water consumption in thirsty rats.

Wydawca

-

Rocznik

Tom

41

Numer

1-3

Opis fizyczny

p.71-77,fig.,ref.

Twórcy

  • Department of Pharmacology and Physiology of the Nervous System, Institute of Psychiatry and Neurology, Warsaw, Poland
  • Department of Pharmacology and Physiology of the Nervous System, Institute of Psychiatry and Neurology, Warsaw, Poland
autor
  • Department of Pharmacology and Physiology of the Nervous System, Institute of Psychiatry and Neurology, Warsaw, Poland
autor
  • Department of Pharmacology and Physiology of the Nervous System, Institute of Psychiatry and Neurology, Warsaw, Poland
  • Institute of Chemistry, University of Gdansk, Gdansk, Poland

Bibliografia

  • 1. Adams D. В. (1979). Brain mechanisms for offense, defense, and submission. Behav. Brain Sci., 2, 201-241.
  • 2. Beaulieu S., DiPaolo T., Cote J., Barden N. (1987). Participation of the central amygdaloid nucleus in the response of adrenocorticotropin secretion to immobilization stress: opposing roles of the noradrenalinergic and dopaminergic systems. Neuroendocrinology, 45, 37-46.
  • 3. Blanchard R. J., Blanchard D. C., Takahaski L. K. (1978). Pain and aggression in the rat. Behav. Neural. Biol., 23, 291-305.
  • 4. Bobrowska J., Leroux P., Maliński E., Przybylski J., Szafranek J., Tonon M. C., Vaudary H., Kupryszewski G. (1981). Thyrotropin releasing hormone and its analogs. I. New syntheses and biological properties of TRH (Pro-NH-Nh₂ ) 3TRH and (2-Picolyl)-TRH. Mat. Med. Pol., 42, 129-135.
  • 5. Eichelman B. (1971). Effect of subcortical lesions on shock-induced aggression in the rat. J. Comp. Physiol. Psychol., 74, 331-339.
  • 6. Fallon J. H. (1981). Histochemical characterisation of dopaminergic, noradrenergic and serotonergic projections to the amygdala. In: The Amygdaloid Complex Ed. Ben-Ari Y., INSERM Symposium No. 20, Elsevier/North-Holland, Amsterdam, pp. 175-183.
  • 7. Funatsu K., Teshima S.. Inanaga K. (1985). Various types of thyrotropin-releasing hormone receptors in discrete brain regions and the pituitary of the rat. J. Neurochem., 45, 390-397.
  • 8. Heal D. J., Green A. R. (1979). Administration of thyrotropin releasing hormone (TRH) to rats releases dopamine in n. accumbens but not n. caudatus. Neuropharmacology, 18, 23-31.
  • 9. Heal D. J., Stoodley N., Elliott J. M., Marsden C. A., Bennett G. W., Youdim M. В. H. (1987). Behavioral and biochemical evidence for the release of noradrenaline in mouse brain by TRH and some of its biologically stable analogous. Neuropharmacology, 26, 313-322.
  • 10. Jellestad F. K., Markowska A., Bakke H. K., Walther B. (1986). Behavioral effects after ibotenic acid, 6-OHDA and electrolytic lesions in the central amygdala nucleus of the rat. Physiol. Behav., 37, 855-862.
  • 11. Johansson O., Hokfelt T. (1980). Thyrotropin releasing hormone, somatostatin, and enkephalin: distribution studies using immunohistochemical techniques. H. Histochem., Cytochem., 28, 364-366.
  • 12. Kostowski W., Plewako M., Bidziński A. (1984). Brain serotonergic neurons: their role in a form of dominance-subordination behavior. Physiol. Behav., 33, 365-371.
  • 13. Malatyńska E., Kostowski W. (1984). Effect of antidepressants on dominance behavior in rats. Pol. J. Pharmacol. Pharm., 36, 531-540.
  • 14. Miczek K. A., Brykczyński Т., Grossman А. Р. (1974). Differential effects of lesions in the amygdala, periamygdaloid cortex and stria terminalis on aggressive behaviors in rats. J. Comp. Physiol. Psychol., 87, 760-771.
  • 15. Miyamoto M., Narumi S., Nagai Y., Shima T., Nagawa Y. (1979). Thyrotropin releasing hormone: hyperactivity and mesolimbic dopamine system in rats. Japan. J. Pharmacol., 29, 335-347.
  • 16. Pellegrino L. J., Pellegrino A. S., Cushman A. J. (1979). A stereotaxic atlas of the rat brain. Plenum Press, New York.
  • 17. Reigle T. J., Avni J., Platz P. A., Schildkraut J. J., Plotnikoff N. P. (1974). Noreinephrine metabolism in the rat brain following acute and chronic administration of thyrotropin releasing hormone. Psychopharmacologia, 37, 1-6.
  • 18. Reny-Palasse V., Poncet J., Rips R. (1987). TRH-induced antinociception: interaction with the opioid systems? Gen. Pharmacol., 18, 179-183.
  • 19. Rodgers R. J., File S. E. (1979). Exploratory behavior and aversive thresholds following intra-amygdaloid application of opiates in rats. Pharmacol. Biochem. Behav., 11, 505-511.
  • 20. Suzuki T., Kohno H., Sakurada T., Tadano T., Kisara K. (1982). Intracranial injection of thyrotropin releasing hormone (TRH) suppresses starvation-induced feeding and drinking in rats. Pharmacol. Biochem. Behav., 17, 249-253.
  • 21. Ursin H., Jellestad F., Cabrera I. G. (1981). The amygdala, exploration and fear. In: The Amygdaloid Complex, Ed. Ben-Ari Y., INSERM Symposium No. 20, Elsevier/North-Holland, Amsterdam, pp. 317-329.
  • 22. Valzelli L. (1981). Psychobiology of Aggression and Violence. Raven Press, New York.
  • 23. Vogel R. A., Frye G. D., Wilson J. H., Kuhn С. M., Mailman R. B., Mueller R. A., Breese G. R. (1980). Attenuation of the effect of punishment by thyrotropin-releasing hormone: comparisons with chlordiazepoxide. J. Pharmacol. Exp. Ther., 212, 153-161.
  • 24. Werka T., Skar J., Ursin H. (1978). Exploration and avoidance in rats with i lesions in amygdala and piriform cortex. J. Comp. Physiol. Psychol., 92, 672-681.

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Bibliografia

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