The lack of influence of some neuropeptides present in the posterior pituitary lobe on the frequency of spontaneous contraction of the isolated heart auricle

• Autorzy: Goraca A. , Traczyk W.Z.
• Języki publikacji: EN

Abstrakty

EN

Gorąca A., Traczyk W. Z.: The lack of influence of some neuropeptides present in the posterior pituitary lobe on the frequncy of spontaneous contraction of the sisolated heart auricle. Acta Physiol. Pol. 1940, 4 (6): Investigations have shown the presence of a cardiodepressant factor in the fluid incubating the posterior pituitary lobe “in situ”, which decreased contraction frequency of the isolated heart auricle (Acta Physiol. Pol., 1984, 35: 460-468). The influence on the spontaneuos contraction frequency of the isolated heart auricle of the following synthetic neuropeptides was determined: substance P, leu-enkephalin, met-enke- phalin, angiotensin II, arg-vasopressin, oxytocin, delta sleep-inducing peptide and atrial natriuretic factor. It was found that the investigated neuropeptides had no effect on the contraction frequency of the isolated auricle of the heart right atrium of two-day-old rat in a concentration from 2.1 × 10⁻⁷ to 1 × 10⁻³ mol/1 in the bathing medium and it was concluded that their biological properties differ from the cardiodepressant factor.

Słowa kluczowe

EN

neuropeptide; posterior pituitary lobe; frequency; spontaneous contraction; isolation; heart auricle; substance P; oxytocin; peptide; atrial natriuretic factor

• Wydawca: -
• Czasopismo: Acta Physiologica Polonica
• Rocznik: 1990
• Tom: 41
• Numer: 7
• Opis fizyczny: p.54-64,fig.,ref.

Twórcy

autor

Goraca A.

• Department of Physiology, Institute of Physiology and Biochemistry, School of Medicine in Lodz, Lindleya 3, 90-131 Lodz, Poland

autor

Traczyk W.Z.

• Department of Physiology, Institute of Physiology and Biochemistry, School of Medicine in Lodz, Lindleya 3, 90-131 Lodz, Poland

Bibliografia

• 1. Border G. В., Harley R. J., Johnson I. S. (1971): Recording system for monitoring automaticity of heart cells in culture. Nature, 231, 531-532.
• 2. de Bold A. J., Borenstein H. B., Veres A. T., Sonnenberg H. (1981): A rapid and potent natriuretic response to intravenous of atrial myocardial extract in rats. Life Sci., 28, 89-94.
• 3. Brownstein M. J., Mroz E. К., Kizer S., Palkovits M., Leeman S. E. (1976): Regional distribution of substance P in the brain of the rat. Brain Res., 116, 299-305.
• 4. Changaris D. G., Keil L. C., Severs W. B. (1978): Angiotensin II immunochemistry of the rat brain. Neuroendocrinology, 25, 257-274.
• 5. Covino B. G. (1963): Cardiac effects of synthetic oxytocin (synthocinon). Am. Heart J., 66, 627-631.
• 6. Couture R., Hassessian H., Gupta A. (1988) Studies on the cardiovascular effects produced by the spinal action of substnce P in rat. J. Cardiovasc. Pharmacol., 11, 270-283.
• 7. Duka T., Höllt V., Przewłocki R., Wesche D. (1978): Distribution of methionine- and leucine-enkephalin within the rat pituitary gland measured by highly specific radioimmunoassays. Biochem. Biophys. Res. Comm., 85, 1119-1127.
• 8. Eiden L. E., Ruth J. A. (1982): Enkephalins modulate the responsiveness of rat atria in vitro to norepinephrine. Peptides, 3, 475-478.
• 9. Feldman S. C., Kastin A. J. (1984): Localization of neurons containing immuno- reactive delta sleep-inducing peptide in the rat brain: an immunocytochemical study. Neuroscience, 11, 303-317.
• 10. Girand P., Castanas E., Patey G., Oliver C., Rossier J. (1983): Regional distribution of methionine-enkephalin-Arg⁶ -Phe⁷-in the rat brain. Comparative study with the distribution of other opioid peptides. J. Neurochem., 41, 154-160.
• 11. Gorąca A., Tranda T., Traczyk W. Z. (1984a): Appearance of a cardiodepressant factor in the medium incubating in situ the posterior pituitary lobe of the rat. I. Isolation of active compound. Acta Physiol. Pol., 35, 460-468.
• 12. Gorąca A., Traczyk W. Z., Konarzewska A. (1984b): The influence of amino-acids, vasopressin and oxytocin on spontaneous contraction of the right auricle of the right atrium of two-day-old rats in vitro. Acta Physiol. Pol., 35, 454-459.
• 13. Gorąca A., Traczyk W. Z. (1988): Appearance of a cardiodepressant factor in the medium incubating in situ the posterior pituitary lobe of the rat. Differentiation from other active compounds. Acta Physiol. Pol., 39, 98-111.
• 14. Guzek J. W., Leśnik H.(1972): Release of vasopressin from the infundibular axons in rats after increasing blood concentrations of calcium and magnesium ions. Annals Med. Sect Pol. Acad. Sci., 17, 153-158.
• 15. Hiwatari M., Satoh K., Angus J. A., Johnston С. I. (1986): No effect of atrial natriuretic factor on cardiac rate, force, and transmitter release. Clin. Exp. Pharmacol. Physiol., 13, 163-168.
• 16. Hökfelt T., Eide R., Johansson O., Terenius L., Stein L. (1977): The distribution of enkephalin-immunoreactive cell bodies in the rat central nervous system. Neurose. Lett., 5, 25-31.
• 17. Kanazawa J., Jessel T. (1976): Post mortem changes and regional distribution of substance P in the rat and mouse nervous system. Brain Res., 117, 362-367.
• 18. Kastin A. J., Nissen C., Schally A. V., Coy D. H. (1978): Radioimmunoassay of DSIP-like material in rat brain. Brain Res. Bull., 3, 691-695.
• 19. Kilcoyne M. M., Hoffman D. L., Zimmerman E. A. (1981): Immunocytochemical localization of angiotensin II and vasopressin in rat hypothalamus: evidence for production in the same neuron. Clin. Sci., 59, 515-605.
• 20. Landgraf R. (1981): Simultaneous measurement of arginine vasopressin and oxytocin in plasma and neurohypophysis by radioimmunoassay. Endocrinologie, 78, 191-204.
• 21. Lefer A. M., Inge T. F. Jr. (1973): Differentiation of a myocardial depressant factor present in shock plasma from known plasma peptides and salts. Proc. Soc. Exp. Biol. Med., 142, 429-433.
• 22. Lefer A. M., Craddock G. B, Cowgill R., Brand E. D. (1966): Performance of papillary muscles isolated from cats in post-oligemic shock. Am. J. Physiol., 211, 687-692.
• 23. Leśnik H. (1972): Release of vasopressin from infundibular axons in rats under the action of drugs changing conduction of impulses in adrenergic and cholinergic synapses. Ann. Med. Sec. Pol. Ac. Sci., 17, 269-273.
• 24. Monnier M., Dudler L.. Schoenenberger G. A. (1973): Humoral transmission of sleep. VIII. Effects of the “sleep factor delta” on cerebral, motor and visceral activities. Pflügers Arch., 345, 23-35.
• 25. Morii N., Nakao K., Sugawara A., Sakamoto M., Suda M., Shimokura M., Kiso Y., Kihara M., Yamori Y., Imura H. (1985): Occurrence of atrial natriuretic polypeptide in brain. Biochem. Biophys. Res. Comm., 127, 413-419.
• 26. Orłowska-Majdak M., Werulik B., Traczyk W. Z. (1978): Release of oxytocin and Substance P-like peptides from the rat posterior pituitary lobe incubated in situ after infusion of hypertonic solution into the third cerebral ventricle. Acta Physiol. Pol., 29, 9-16.
• 27. Osborn J. W. Jr., Skelton M. M., Cowley A. W. Jr. (1987): Hemodynamic effects of vasopressin compared with angiotensin II in conscious rats. Am. J. Physiol., 252, H628-H637.
• 28. Quirion R., Dalpe M., De Lean A., Gutkowska J., Cantin M., Genest J. (1984): Atrial natriuretic factor (ANF) binding sites in brain and related structures. Peptides 5, 1167-1172.
• 29. Rannekleiv O. K., Kelly M. J., Eskay R. L. (1984): Distribution of immuno- reactive substance P neurons in the hypothalamus and pituitary of the rhesus monkey. J. Comp. Neurology, 224, 51-59.
• 30. Rossier J., Battenberg E., Pittman Q., Bayon A., Koda L., Miller R., Guillemin R., Bloom F. (1979): Hypothalamic enkephalin neurons may regulate the neurohypophysis. Nature, 277, 653-655.
• 31. Ruth J. A., Eiden L. E. (1984): Leucine-enkephalin modulation of catecholamine positive chronotropy in rat atria is receptor-specific and calcium-dependent. Neuropeptides, 4, 101-108.
• 32. Saunders W. S., Thornhill J. A. (1985): No inotropic action of enkephalins or enkephalin derivatives on electrically-stimulated atria isolated from lean and obese rats. Br. J. Pharmacol., 85, 513-522.
• 33. Schneiderman N., Monnier M., Hosli L. (1966): Humoral transmission of sleep. IV. Cerebral and visceral effects of sleep dialysate. Pflügers Arch., 288, 65-80.
• 34. Seymour A. A., Sweet Ch. S., Stabilito I, I., Emmert S. E. (1987): Cardiac and hemodynamic responses to synthetic atrium natriuretic factor in rats. Life Sci., 40, 511-519.
• 35. Severs W. B., Daniels A. E., Smookler H. H., Kinnard W. J., Buckley J. P. (1966): Interrelationship between angiotensin II and the Sympathic nervous system. J. Pharmacol. Exp. Therap., 153, 530-537.
• 36. Simantov R., Kuhar M. J., Uhl G. R., Snyder S. H. (1977): Opioid peptide enkephalin: Immunocytochemical mapping in rat central nervous system. Proc. Natl. Acad. Sci. USA, 74, 2167-2171.
• 37. Sinding Ch., Seif S. M., Robinson A. G. (1980): Levels of neurohypophyseal peptides in the rat during the first month of life. I Basal levels in plasma, pituitary and hypothalamus. Endocrinology, 107, 749-754.
• 38. Sirett N. E., McLean A. S., Bray J. J., Hubbard J. J. (1977): Distribution of angiotensin II receptors in rat brain. Brain Res., 122, 299-312.
• 39. Skofitsch G., Jacobowitz D. M., Eskay R. L., Zamir N. (1985): Distribution of atrial natriuretic factor-like immunoreactive neurons in the rat brain. Neuroscience, 16, 917-948.
• 40. Sobczak Z. (1978): Vasopressin release from incubated in situ posterior pituitary lobe after intraventricular injection of carbachol or atropine. Endocrinologie, 72, 205-213.
• 41. Swaab D. F., Nijveldt F., Pool C. W. (1975): Distribution of oxytocin and vasopressin in the rat supraoptic and paraventricular nucleus. J. Endocr., 67, 461-462.
• 42. Traczyk W. Z. (1972): Vasopressin release from incubated in situ posterior pituitary in rats. Bull Acad. Polon. Sci, Ser. Sci Biol., 20, 351-356.
• 43. Traczyk W. Z. (1974): Substance P and vasopressin release from incubated in situ posterior pituitary lobe in rats. Bull. Acad. Polon. Sci. Ser. Sci. Biol., 22, 731-735.
• 44. Traczyk W. Z., Strumiłło-Dyba E. (1977): Substance P-like peptides and vasopressin release from posterior pituitary lobe incubated in situ after intracarotid injections of hypertonic solution in rats. Acta Physiol. Pol., 28, 397-404.
• 45. Van Leeuwen F. W., Swaab D. F. (1977): Specific immunoelectronmicroscopic localization of vasopressin and oxytocin in the neurohypophysis of the rat. Cell. Tiss. Res., 177, 493-501.
• 46. Unger T., Rascher W., Schuster Ch., Pavlovitch R., Schomig A., Dietz R., Ganten D. (1981): Central blood pressure effects of substance P and angiotensin II: Role of the sympathetic nervous system and vasopressin. Eur J. Pharmacol., 71, 33-42.