Concentration of magnesium in the serum and the ability status of patients with relapsing-remitting multiple sclerosis

• Języki publikacji: EN

Abstrakty

EN

Multiple sclerosis (MS) is the most common autoimmune disease affecting the central nervous system, characterized by the presence of scattered foci of demyelination in the brain and spinal cord. Magnesium (Mg) has a significant influence on the nervous system and the immune system. The aim of this study was to evaluate the influence of the concentration of Mg in the serum on the ability status of patients with MS. The study group consisted of 101 adults with diagnosed relapsing remitting MS. All participants were investigated on the Expanded Disability Status Scale. The control group included 41 people. The concentration of Mg in the serum was determined by the flame atomic absorption spectrometry method. The patients completed a survey and a 24-hour dietary interview. In patients with MS, the percentage of respondents with normal magnesium content was significantly lower than in the control group (p < 0.05). The study proved that patients with normal Mg serum concentration levels were in better clinical condition, particularly with respect to the function of the pyramidal tract (p = 0.007) and sphincters (p = 0.002), than patients with inadequate levels of Mg in the serum. External factors such as gender, smoking, immunomodulating medications or dietary supplements of Mg were found to have no effect on the concentration of Mg in the serum of MS patients. The results of our study suggest that an abnormal concentration of Mg in the serum of MS patients should be recognized and corrected, as this may improve the health status of people with MS.

• Wydawca: -
• Czasopismo: Journal of Elementology
• Rocznik: 2017
• Tom: 22
• Numer: 2
• Opis fizyczny: p.671-679,ref.

Twórcy

Identyfikatory

DOI

10.5601/jelem.2016.21.4.1156