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2013 | 57 | 3 |

Tytuł artykułu

P-R interval in porcine model of chronic tachycardia-induced cardiomyopathy

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
The aim of the study was to assess the atrioventricular conduction in the model of porcine pacing induced tachycardiomyopathy. Fifty-one swine were examined: 27 were paced and 24 served as a control group. Every 4 weeks, the animals were anaesthetised for 1 h and an ECG Holter was performed. Thirty minutes after the onset of anaesthesia, P-R and R-R intervals were measured. Each result was assigned to the subgroup according to the animal's weight and the presence or absence of previous pacing. P-R interval was longer in animals after at least 4 weeks of rapid ventricular stimulation than in adjusted group of the animals according to the body mass. Multivariate analysis has showed that longer P-R interval was related to male gender, higher body mass, slower heart rate, and history of previous pacing. Chronic ventricular pacing led to the slowing of atrioventricular conduction. The presence of differences in the duration of R-R intervals between groups was only found in swine weighing 120-139 kg. The R-R interval was shorter in paced animals, whereas PR interval was longer in that group, indicating that PR prolongation is related to electrical or structural remodelling of the cardiac conductive tissue but not increased sympathetic nervous system activity, which is expected to produce corresponding changes in PR and R-R intervals.

Słowa kluczowe

Wydawca

-

Rocznik

Tom

57

Numer

3

Opis fizyczny

p.437-441,fig.,ref.

Twórcy

  • Department of Surgery, Wroclaw University of Environmental and Life Sciences, 50-366 Wroclaw, Poland
autor
  • Department of Emergency Medicine, Wroclaw Medical University, 50-366 Wroclaw, Poland Research and Development Centre 3Regional Specialist Hospital in Wroclaw, 51-124 Wroclaw, Poland
autor
  • Department of Internal Diseases with Clinic for Horses, Dogs, and Cats, Wroclaw University of Environmental and Life Sciences, 50-366 Wroclaw, Poland
  • Department of Food Hygiene and Consumer Health Protection, Wroclaw University of Environmental and Life Sciences, 50-366 Wroclaw, Poland
  • Department of Internal Diseases with Clinic for Horses, Dogs, and Cats, Wroclaw University of Environmental and Life Sciences, 50-366 Wroclaw, Poland
  • Department of Food Hygiene and Consumer Health Protection, Wroclaw University of Environmental and Life Sciences, 50-366 Wroclaw, Poland
  • Regional Specialist Hospital in Wroclaw, 51-124 Wroclaw, Poland
autor
  • Regional Specialist Hospital in Wroclaw, 51-124 Wroclaw, Poland
  • Department of Biochemistry, Pharmacology and Toxicology, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, 50-366 Wroclaw, Poland
autor
  • Regional Specialist Hospital in Wroclaw, 51-124 Wroclaw, Poland
  • Department of Food Hygiene and Consumer Health Protection, Wroclaw University of Environmental and Life Sciences, 50-366 Wroclaw, Poland
autor
  • Regional Specialist Hospital in Wroclaw, 51-124 Wroclaw, Poland
  • Department of Biochemistry, Pharmacology and Toxicology, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, 50-366 Wroclaw, Poland
autor
  • Regional Specialist Hospital in Wroclaw, 51-124 Wroclaw, Poland
  • Department of Biochemistry, Pharmacology and Toxicology, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, 50-366 Wroclaw, Poland
autor
  • Regional Specialist Hospital in Wroclaw, 51-124 Wroclaw, Poland
  • Department of Biochemistry, Pharmacology and Toxicology, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, 50-366 Wroclaw, Poland
autor
  • Department of Internal Diseases with Clinic for Horses, Dogs, and Cats, Wroclaw University of Environmental and Life Sciences, 50-366 Wroclaw, Poland
  • Regional Specialist Hospital in Wroclaw, 51-124 Wroclaw, Poland
autor
  • Regional Specialist Hospital in Wroclaw, 51-124 Wroclaw, Poland
  • Department and Clinic of Internal and Occupational Diseases and Hypertension, Wroclaw University of Environmental and Life Sciences, 50-366 Wroclaw, Poland
autor
  • Department of Heart Diseases, Wroclaw Medical University, 50-367 Wroclaw, Poland
  • Centre for Heart Diseases, Military Hospital, 50-891 Wroclaw, Poland
  • Centre for Heart Diseases, Military Hospital, 50-891 Wroclaw, Poland

Bibliografia

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Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

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