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2019 | 79 | 2 |
Tytuł artykułu

Autism spectrum disorder and mercury toxicity: use of genomic and epigenetic methods to solve the etiologic puzzle

Autorzy
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
Autism spectrum disorder (ASD) is an increasingly prevalent neurodevelopmental condition of unknown etiology. Mercury is a common, highly neurotoxic heavy metal. The similarities of neurologic manifestations of mercury exposure and ASD raise an intriguing hypothetical question: Is ASD, at least partially, a manifestation of mercury toxicity? The fetus is particularly vulnerable to mercury exposure from the “double jeopardy” combination of the genetics of his mother and his own genetics, as relates to mercury toxicity. In this paper, I review the evidence suggesting relationships between ASD and mercury toxicity. I suggest ways to confirm these relationships with genetic and epigenetic research. I propose a hypothesis associating mercury toxicity with ASD. This may present opportunities for further research in prevention and treatment of ASD.
Słowa kluczowe
Wydawca
-
Rocznik
Tom
79
Numer
2
Opis fizyczny
p.113-125,ref.
Twórcy
  • Yampa Valley Medical Associates, Steamboat Springs, USA
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Typ dokumentu
Bibliografia
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Identyfikator YADDA
bwmeta1.element.agro-0c939726-b79c-4e3a-8cfc-43d516cdb2fc
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