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2018 | 64 | 1 |

Tytuł artykułu

Expression on hypoxia-inducible factor-1α in human tegumentary leishmaniosis caused by Leishmania braziliensis

Treść / Zawartość

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
Several immune markers have been studied in controlling American tegumentary leishmaniosis based on mouse models. However, there is a lack of studies regarding human tegumentary leishmaniosis caused by Leishmania braziliensis. In this study, hypoxia-inducible factor-1α was found to be an important effector element in the localized control of human cutaneous and mucocutaneous lesions.

Słowa kluczowe

Wydawca

-

Rocznik

Tom

64

Numer

1

Opis fizyczny

p.73-76,fig.,ref.

Twórcy

autor
  • Department of Tropical Medicine, Federal University of Pernambuco, Prof. Moraes Rego Av., 50670-901, Recife, Pernambuco, Brazil
  • Department of Tropical Medicine, Federal University of Pernambuco, Prof. Moraes Rego Av., 50670-901, Recife, Pernambuco, Brazil
autor
  • Department of Parasitology, Aggeu Magalhães Research Center, Prof. Moraes Rego Av., 50670-420, Recife, Pernambuco, Brazil
  • Department of Parasitology, Aggeu Magalhães Research Center, Prof. Moraes Rego Av., 50670-420, Recife, Pernambuco, Brazil
autor
  • Department of Pathology, Federal University of Pernambuco, Prof. Moraes Rego Av., 50670-901, Recife, Pernambuco, Brazil
autor
  • Department of Animal Biology, State University of Campinas, Monteiro Lobato St. 255, 13083-862, Campinas, Sao Paulo, Brazil

Bibliografia

  • [1] Semenza G.L. 2016. Targeting hypoxia-inducible factor 1 to stimulate tissue vascularization. The Journal of Investigative Medicine 64: 361-363. doi:10.1097/JIM.0000000000000206
  • [2] Degrossoli A., Bosetto M.C., Lima C.B.C., Giorgio S. 2007. Expression of hypoxia-inducible factor-1alpha in mononuclear phagocytes infected with Leishmania amazonensis. Immunology Letters 114: 119-125. doi:10.1016/j.imlet.2007.09.009
  • [3] Tang C. M., Yu J. 2013. Hypoxia-inducible factor-1 as a therapeutic target in cancer. Journal of Gastroenterology and Hepatology 28: 401-405. doi:10.1111/jgh.12038
  • [4] Bhandari T., Nizet V. 2014. Hypoxia-inducible factor (HIF) as a pharmacological target for prevention and treatment of infectious diseases. Infection Diseases and Therapy 3: 159-174. doi:10.1007/s40121-014-0030-1
  • [5] Kelly B., O’Neill L.A. 2015. Metabolic reprogramming in macrophages and dendritic cells in innate immunity. Cell Research 25: 771-784. doi:10.1038/cr.2015.68
  • [6] Bzowska M., Nogieć A., Bania K., Zygmunt M., Zarębski M., Dobrucki J., Guzik K. 2017. Involvement of cell surface 90 KDa heat shock protein (HSP90) in pattern recognition by human monocyte-erived macrophages. Journal of Leucocyte Biology 102: 763-774. doi:10.1189/jlb.2MA0117-019R
  • [7] Wiesgigl M., Clos J. 2001. Heat shock protein 90 homeostasis controls stage differentiation in Leishmania donovani. Molecular Biology Cell 12: 3307-3316.
  • [8] Araújo A.P., Arrais-Silva W.W., Giorgio S. 2012. Infection by Leishmania amazonensis in mice: a potential model for chronic hypoxia. Acta Histochemica 114: 797-804. doi:10.1016/j.acthis.2012.01.007
  • [9] Araújo A.P., Giorgio S. 2015. Immunohistochemical evidence of stress and inflammatory markers in mouse models of cutaneous leishmaniosis. Archives of Dermatological Research 307: 671-682. https://doi.org/ 10.1007/s00403-015-1564-0
  • [10] Singh A.K., Mukhopadhyay C., Biswas S., Singh V.K., Mukhopadhyay C.K. 2012. Intracellular pathogen Leishmania donovani activates hypoxia inducible factor-1 by dual mechanism for survival advantage within macrophage. PLoS One 7: e38489. doi:10.1371/journal.pone.0038489.
  • [11] Werth N., Beerlage C., Rosenberger C., Yazdi A.S., Edelmann M., Amr A., Bernhardt W., von Eiff C., Becker K., Schäfer A., Peschel A., Kempf V.A.J. 2010. Activation of hypoxia inducible factor 1 is a general phenomenon in infections with human pathogens. PLoS One 5: e11576. doi:10.1371/journal.pone.0011576
  • [12] Fraga C.A.C., de Oliveira M.V.M., Alves L.R., de Sousa A.A., de Paula A.M.B., Guimarães A.L.S., Oliveira M.V.M., Viana A.G., Carvalho S.F.G., Botelho A.C.C. 2012. Immunohistochemical profile of HIF-1α, VEGF-A, VEGFR2 and MMP9 proteins in tegumentary leishmaniasis. Anais Brasileiros de Dermatologia 87: 709-713. http://dx.doi.org/10.1590/S0365-05962012000500006.
  • [13] Schatz V., Strüssmann Y., Mahnke A., Schley G., Waldner M., Ritter U., Wild J., Willam C., Dehne N., Brüne B., McNiff J.M., Colegio O.R., Bogdan C., Jantsch J. 2016. Myeloid cell-derived HIF-1α promotes control of Leishmania major. The Jornal of Immunology 197: 4034-4041. https://doi.org/ 10.4049/jimmunol.1601080
  • [14] Aherne W. 1967. Methods of counting discrete tissue components in microscopical sections. The Journal of the Royal Microscopical Society 87: 493-508. doi:10.1111/j.1365-2818.1967.tb04529.x
  • [15] Schönian G., Nasereddin A., Dinse N., Schweynocha C., Schalligc H.D.F.H., Presbera W., Jaffeb C.L. 2003. PCR diagnosis and characterization of Leishmania in local and imported clinical samples. Diagnostic Microbiology and Infectious Disease 47: 349-358. https://dx.doi.org/10.1016/s0732-8893(03)00093-2
  • [16] da Silva L.A., Sousa C.S., Graça G.C., Porrozzi R., Cupolillo E. 2010. Sequence analysis and PCR-RFLP profiling of the hsp70 gene as a valuable tool for identifying Leishmania species associated with human leishmaniasis in Brazil. Infection, Genetics and Evolution 10: 77-83. https://doi.org/ 10.1016/j.meegid.2009.11.001

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

bwmeta1.element.agro-0ac9135a-4ed3-4beb-88fd-82ff8f64772a
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