Rola hormonów oraz czynników wzrostowych w implantacji zarodka u ssaków

• Autorzy: Bukowska D. , Kempisty B. , Ciesiolka S. , Piotrowska H. , Antosik P. , Jaskowski J. M. , Nowicki M.

Warianty tytułu

EN

Role of hormones and growth factors in the implantation of embryos in mammals

• Języki publikacji: PL

Abstrakty

EN

Implantation is crucial for normal pregnancy and embryo development. Synchronized interaction between the embryo and the endometrium is necessary for the embryo to reach the endometrial site of implantation and for the blastocyst to achieve its normal developmental capacity. The process of implantation is divided into three stages: apposition, adhesion, and invasion. The systems that regulate the course of these mechanisms are based on the secretion of hormones and on the synthesis of selected growth factors. Disruptions in these factor-derived signaling pathways prevent implantation and/or result in abortion, thus reducing fertility. This review presents the molecular basis of embryo implantation. This knowledge may be used in the future to evaluate the ability of potential recipients to receive embryos and to be used for embryo transfer.

Słowa kluczowe

PL

ssaki; rozrod zwierzat; ciaza; zarodki; implantacja; mechanizmy implantacji; hormony; hormony jajnikowe; progesteron; 17-beta-estradiol; czynnik wzrostu epidermalny; czynnik wzrostu srodblonka naczyniowego; insulinopodobny czynnik wzrostu

• Wydawca: -
• Czasopismo: Medycyna Weterynaryjna
• Rocznik: 2014
• Tom: 70
• Numer: 03
• Opis fizyczny: s.157-160,bibliogr.

Twórcy

autor

Bukowska D.

• Katedra Weterynarii, Wydział Hodowli i Biologii Zwierząt, Uniwersytet Przyrodniczy w Poznaniu, ul.Wojska Polskiego 52, 60-628 Poznań

autor

Kempisty B.

• Katedra i Zakład Anatomii Prawidłowej, Wydział Lekarski II, Uniwersytet Medyczny im.Karola Marcinkowskiego w Poznaniu, ul.Święcickiego 6, 60-781 Poznań

autor

Ciesiolka S.

• Katedra i Zakład Histologii i Embriologii, Wydział Lekarski II, Uniwersytet Medyczny im.Karola Marcinkowskiego w Poznaniu, ul.Święcickiego 6, 60-781 Poznań

autor

Piotrowska H.

• Katedra i Zakład Toksykologii, Wydział Farmaceutyczny, Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, ul.Dojazd 30, 60-631 Poznań

autor

Antosik P.

• Katedra Weterynarii, Wydział Hodowli i Biologii Zwierząt, Uniwersytet Przyrodniczy w Poznaniu, ul.Wojska Polskiego 52, 60-628 Poznań

autor

Jaskowski J. M.

• Katedra Weterynarii, Wydział Hodowli i Biologii Zwierząt, Uniwersytet Przyrodniczy w Poznaniu, ul.Wojska Polskiego 52, 60-628 Poznań

autor

Nowicki M.

• Katedra i Zakład Histologii i Embriologii, Wydział Lekarski II, Uniwersytet Medyczny im.Karola Marcinkowskiego w Poznaniu, ul.Święcickiego 6, 60-781 Poznań

Bibliografia

• 1. Albrecht E. D., Aberdeen G. W., Niklaus A. L., Babischkin J. S., Suresch D. L., Pepe G. J.: Acute temporal regulation of vascular endothelial growth/permeability factor expression and endothelial morphology in the baboon endometrium by ovarian steroids. J. Clin. Endocrinol. Metab. 2003, 88, 2844-2852.
• 2. Ashworth M. D., Ross J. W., Stein D. R., Allen D. T., Spicer L. J., Geisert R. D.: Endocrine disruption of uterine insulin-like growth factor expression in the pregnant gilt. Reproduction 2005, 130, 545-551.
• 3. Bukowska D., Kempisty B., Jackowska M., Woźna M., Antosik P., Piotrowska H., Jaśkowski J. M.: Analysis of integrins and vascular endothelial growth factor isoforms mRNA expression in the canine uterus during perimplantation period. PJVS 2011, 14, 253-258.
• 4. Bukowska D., Kempisty B., Jackowska M., Woźna M., Antosik P., Piotrowska H., Jaśkowski J. M.: Differential expression of epidermal growth factor and transforming growth factor beta isoforms in dog endometrium during different periods of the estrus cycle. PJVS 2011, 14, 259-264.
• 5. Bukowska D., Kempisty B., Piotrowska H., Zawierucha P., Brussow K. P., Jaśkowski J. M., Nowicki M.: The in vitro culture supplements and selected aspects of canine oocytes maturation. PJSV 2012, 15, 199-205.
• 6. Carson D. D., Bagchi I., Dey S. K., Enders A. C., Fazleabas A. T., Lessey B. A., Yoshinaga K.: Embryo implantation. Dev. Biol. 2000, 223, 217-237.
• 7. Cheon Y. P., Xu X., Bagchi M. K., Bagchi I. C.: Immune-responsive gene 1 is a novel target of progesterone receptor and plays a critical role during implantation in the mouse. Endocrinology 2003, 144, 5623-5630.
• 8. Deanesly R.: Normal implantation in ovariectomized guinea pigs. Nature 1960, 186, 327-328.
• 9. Denley A., Carroll J. M., Brierley G. V., Cosgrove L., Wallace J., Forbes B., Roberts C. T. Jr: Differential activation of insulin receptor substrates 1 and 2 by insulin-like growth factor-activated insulin receptors. Mol. Cell Biol. 2007, 27, 3569-3577.
• 10. Enders A. C., Schlafke S., Hendrickx A. G.: Differentiation of the embryonic disc, amnion, and yolk sac in the rhesus monkey. Am. J. Anat. 1986, 177, 161-185.
• 11. Fabian D., Il’ková G., Rehák P., Czikková S., Baran V., Koppel J.: Inhibitory effect of IGF-I on induced apoptosis in mouse preimplantation embryos cultured in vitro. Theriogenology 2004, 61, 745-755.
• 12. Giudice L. C., Conover C. A., Bale L., Faessen G. H., Ilg K., Sun I., Imani B., Suen L. F., Irwin J. C., Christiansen M., Overgaard M. T., Oxvig C.: Identification and regulation of the IGFBP-4 protease and its physiological inhibitor in human trophoblasts and endometrial stroma: evidence for paracrine regulation of IGF-II bioavailability in the placental bed during human implantation. J. Clin. Endocrinol. Metab. 2002, 87, 2359-2366.
• 13. Iwamoto R., Yamazaki S., Asakura M., Takashima S., Hasuwa H., Miyado K., Adachi S., Kitakaze M., Hashimoto K., Raab G., Nanba D., Higashiyama S., Hori M., Klagsbrun M., Mekada E.: Heparin-binding EGF-like growth factor and ErbB signaling is essential for heart function. PNAS 2003, 100, 3221-3226.
• 14. Jackowska M., Kempisty B., Woźna M., Piotrowska H., Antosik P., Zawierucha P., Bukowska D., Nowicki M., Jaśkowski J. M., Brüssow K. P.: Differential expression of GDF9, TGFB1, TGFB2 and TGFB3 in porcine oocytes isolated from follicles of different size before and after culture in vitro. Acta Vet. Hung. 2013, 61, 99-115.
• 15. Kempisty B., Antosik P., Bukowska D., Jackowska M., Lianeri M., Jaśkowski J. M., Jagodziński P. P.: Analysis of selected transcript levels in porcine spermatozoa, oocytem, zygotes and twocell stage embryos. Reprod. Fertil. Dev. 2008, 20, 513-518.
• 16. Kempisty B., Woźna M., Piotrowska H., Bukowska D., Jackowska M., Antosik P., Jaśkowski J. M., Brüssow K. P.: The expression of genes encoding zona pellucida glycoproteins in canine cumulus-oocyte complexes cultured in vitro in media supplemented with progesterone and estradiol. Theriogenology 2012, 77(3), 684-693.
• 17. Khatua A., Wang X., Ding T., Zhang Q., Reese J., DeMayo F. J., Paria B. C.: Indian hedgehog, but not histidine decarboxylase or amphiregulin, is a progesterone-regulated uterine gene in hamsters. Endocrinology 2006, 147, 4079-4092.
• 18. Lee K. Y., DeMayo F. J.: Animal models of implantation. Reproduction 2004, 128, 679-695.
• 19. Lei W., Feng X. H., Deng W. B., Ni H., Zhang Z. R., Jia B., Yang X. L., Wang T. S., Liu J. L., Su R. W., Liang X. H., Qi Q. R., Yang Z. M.: Progesterone and DNA damage encourage uterine cell proliferation and decidualization through up-regulating ribonucleotide reductase 2 expression during early pregnancy in mice. J. Biol. Chem. 2012, 287, 15174-15192.
• 20. Makker A., Singh M. M., Chowdhury S. R., Maitra S. C., Kamboj V. P.: Uterine estradiol and P4 receptor concentration in relation to circulating hormone levels and histoarchitecture during high endometrial sensitivity and induced decidualization in guinea pigs. J. Steroid. Biochem. Mol. Biol. 1994, 48, 535-543.
• 21. McLaren A.: The Embryo. Cambridge, UK: Cambridge University Press 1990.
• 22. Paria B. C., Ma W., Tan J., Raja S., Das S. K., Dey S. K., Hogan B. L.: Cellular and molecular responses of the uterus to embryo implantation can be elicited by locally applied growth factors. PNAS 2001, 98, 1047-1052.
• 23. Rageh M. A., Moussad E. E., Wilson A. K., Brigstock D. R.: Steroidal regulation of connective tissue growth factor (CCN2; CTGF) synthesis in the mouse uterus. Mol. Pathol. 2001, 54, 338-346.
• 24. Reese J., Brown N., Das S. K., Dey S. K.: Expression of neu differentiation factor during the periimplantation period in the mouse uterus. Biol. Reprod. 1998, 58, 719-727.
• 25. Rowe A. J., Wulff C., Fraser H. M.: Localization of mRNA for vascular endothelial growth factor (VEGF), angiopoietins and their receptors during the peri-implantation period and early pregnancy in marmosets (Callithrix jacchus). Reproduction 2003, 126, 227-238.
• 26. Savage C. R. Jr, Hash J. H., Cohen S.: Epidermal growth factor. Location of disulfide bonds. J. Biol. Chem. 1973, 248, 7669-7672.
• 27. Spencer T. E., Stagg A. G., Joyce M. M., Jenster G., Wood C. G., Bazer F. W., Wiley A. A., Bartol F. F.: Discovery and characterization of endometrial epithelial messenger ribonucleic acids using the ovine uterine gland knockout model. Endocrinology 1999, 140, 4070-4080.
• 28. Sternlicht M. D., Sunnarborg S. W., Kouros-Mehr H., Yu Y., Lee D. C., Werb Z.: Mammary ductal morphogenesis requires paracrine activation of stromal EGFR via ADAM17-dependent shedding of epithelial amphiregulin. Development. 2005, 132, 3923-3933.
• 29. Takamoto N., Zhao B., Tsai S. Y., DeMayo F. J.: Identification of Indian hedgehog as a P4-responsive gene in the murine uterus. Mol. Endocrinol. 2002, 16, 2338-2348.
• 30. Tamura K., Hara T., Kutsukake M., Iwatsuki K., Yanagida M., Yoshie M., Kogo H.: Expression and the biological activities of insulin-like growth factor-binding protein related protein 1 in rat uterus during the periimplantation period. Endocrinology 2004, 145, 5243-5251.
• 31. Tsark E. C., Adamson E. D., Withers G. E. III, Wiley L. M.: Expression and function of amphiregulin during murine preimplantation development. Mol. Reprod. Dev. 1997, 47, 271-283.
• 32. Ullrich A., Schlessinger J.: Signal transduction by receptors with tyrosine kinase activity. Cell 1990, 61, 203-212.
• 33. Wang T. H., Chang C. L., Wu H. M., Chiu Y. M., Chen C. K., Wang H. S.: Insulin-like growth factor-II (IGF-II), IGF-binding protein-3 (IGFBP-3), and IGFBP-4 in follicular fluid are associated with oocyte maturation and embryo development. Fertil. Steril. 2006, 86, 1392-1401.
• 34. Welter H., Wollenhaupt K., Tiemann U., Einspanier R.: Regulation of the VEGF-system in the endometrium during steroid-replacement and early pregnancy of pigs. Exp. Clin. Endocrinol. Diabetes 2003, 111, 33-40.
• 35. Wilcox A. J., Baird D. D., Weinberg C. R.: Time of implantation of the conceptus and loss of pregnancy. NEJM 1999, 340, 1796-1799.
• 36. Wimsatt W. A.: Some comparative aspects of implantation. Biol. Reprod. 1975, 12, 1-40.
• 37. Wollenhaupt K., Kettler A., Brüssow K. P., Schneider F., Kanitz W., Einspanier R.: Regulation of the expression and bioactivation of the epidermal growth factor receptor system by estradiol in pig oviduct and endometrium. Reprod. Fertil. Dev. 2001, 13, 167-176.
• 38. Yarden Y.: The EGFR family and its ligands in human cancer. Signalling mechanisms and therapeutic opportunities. EJC 2001, 37 (Suppl 4), S3–S8.
• 39. Yue Z. P., Yang Z. M., Li S. J., Wang H. B., Harper M. J.: Epidermal growth factor family in rhesus monkey uterus during the menstrual cycle and early pregnancy. Mol. Reprod. Dev. 2000, 55, 164-174.
• 40. Zhu L. J., Bagchi M. K., Bagchi I. C.: Attenuation of calcitonin gene expression in pregnant rat uterus leads to a block in embryonic implantation. Endocrinology 1998, 139, 330-339.