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2011 | 67 | 02 |

Tytuł artykułu

Rozwój limfocytów B i T w centralnych narządach limfatycznych ptaków

Warianty tytułu

EN
Development of B and T lymphocytes in primary lymphoid organs in birds

Języki publikacji

PL

Abstrakty

EN
The avian primary lymphoid organs, the bursa of Fabricius and the thymus, are crucial to the normal development of B and T lymphocytes in birds. Birds use gene conversion to produce different classes of immunoglobulins and this process occurs in the bursa of the Fabricius. The microenvironment of the bursa selectively expands those B-cell precursors that have undergone productive V(D)J recombination. On the other hand, the thymus constitutes the microenvironment for T lymphocyte differentiation and the acquisition of self-tolerance. Production of T cells in the thymus is controlled by a combination of positive and negative selection. The differentiation of T cells proceeds along two pathways characterized by the expression of αβ or γδTCRs. Immunologically mature lymphocytes enter the circulation and colonize the peripheral lymphoid organs.

Wydawca

-

Rocznik

Tom

67

Numer

02

Opis fizyczny

s.97-100,bibliogr.

Twórcy

autor
  • Katedra Epizootiologii z Kliniką Ptaków i Zwierząt Egzotycznych, Wydział Medycyny Weterynaryjnej, Uniwersytet Przyrodniczy we Wrocławiu, Pl.Grunwaldzki 45, 50-366 Wrocław
autor

Bibliografia

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Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

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