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Czasopismo
Cellular and Molecular Biology Letters
Rocznik
2005
Tom
10
Numer
Suppl.2
Identyfikatory
Okładka
Zawartość wolumenu
Suppl.2
artykuł:
Multiple molecular recognition mechanisms. Cytochrome P450 - a case study
(
Wade R. C.
,
Motiejunas D.
,
Schleinkofer K.
,
Sudarko
,
Winn P. J.
,
Banerjee A.
)
artykuł:
Target flexibility in molecular recognition
(
McCammon J. A.
)
artykuł:
The P. falciparum CDK family: structural studies and implications for inhibitor design
(
Merckx A.
,
Zawaira A.
,
Holton S.
,
Doerig C.
,
Noble M.
,
Endicott J.
)
artykuł:
Searching for inhibitors of CDPK as potential drugs against parasites?
(
Klimecka M.
,
Szczegielniak J.
,
Koper L.
,
Koslinski M.
,
Muszynska G.
)
artykuł:
Protein kinases of trypanosomatids as drug targets
(
Mottram J. C.
,
Naula C.
,
Hammarton T.
,
Parsons M.
)
artykuł:
Reversible phosphorylation of histidine residues in vertebrate proteins
(
Klumpp S.
,
Maeurer A.
,
Wieland T.
,
Krieglstein J.
)
artykuł:
Dynamics of human CDK2 and CDK5 studied by computer simulations
(
Otyepka M.
,
Bartova I.
,
Kriz Z.
,
Koca J.
)
artykuł:
Evaluation of 3-carboxy-4-[1H]-quinolones as inhibitors of human protein casein kinase 2
(
Golub A. G.
,
Bdzhola V. G.
,
Yakovenko O. Y.
,
Sapelkin V. M.
,
Yarmoluk S. M.
)
artykuł:
Dependence of aminoglycoside 3'-phosphotransferase VIII activity and antibiotic resistance on Ca2plus - dependent protein serine-threonine kinases in actinomycetes
(
Danilenko V. N.
,
Elizarov S. M.
,
Alekseeva M. G.
)
artykuł:
Implementation of orbital graph model for partial atom charges definition in virtual screening techniques
(
Yakovenko O. Y.
,
Golub A. G.
,
Bdzhola V. G.
,
Yarmoluk S. M.
)
artykuł:
ALK 5 [TGF beta RI] inhibitors: In-vitro and in-vivo characterization of novel orally active pteridines
(
Chakravarty S.
,
Dugar S.
)
artykuł:
The physical nature of cAMP-dependent protein kinase catalytic activity: AB initio differential transition state stabilization analysis of the key active site residues
(
Szarek P.
,
Dyguda E.
,
Sokalski W. A.
,
Cheng Y.
,
Zhang Y.
,
McCammon J. A.
)
artykuł:
Targeting malaria with specific CDK inhibitors
(
Geyer J. A.
,
Kathcart A. K.
,
Bhattacharjee A. K.
,
Chen Y.
,
Cortes E. A.
,
Prigge S. T.
,
Waters N. C.
)
artykuł:
Advances in the structural biology, design and clinical development of Bcr-Abl kinase inhibitors for the treatment of chronic myelogenous leukemia
(
Manley P. W.
,
Cowan-Jacob S.
,
Mestan J.
)
artykuł:
Controlling substrate specificity in protein kinases through chemical clamping
(
Adams J. A.
)
artykuł:
The selectivity of pharmacological inhibitors of cyclin-dependent kinases [CDKS] and glycogen synthase kinase-3 [GSK-3]
(
Meijer L.
)
artykuł:
Manipulation of alternative splicing by specific inhibitors of SR protein kinases
(
Hagiwara M.
)
artykuł:
Classification and characterization of natural protein inhibitors of protein kinases
(
Meglicz A.
,
Leluk J.
,
Lesyng B.
)
artykuł:
Rapid protein-ligand docking using soft modes from MD simulations to account for protein deformability: application to protein kinase-ligand interactions
(
Zacharias M.
)
artykuł:
Signalling protein inhibitors via the combinatorial modification of peptide scaffolds
(
Lawrence D. S.
)
artykuł:
The role of SMG-1, a member of the PIKK [phosphoinositide 3-kinase related kinases] family, in mRNA surveillance; Molecular mechanism and therapeutic implications
(
Ohno S.
)
artykuł:
Tetrabromobenzotriazole [TBBt] and tetrabromobenzimidazole [TBBz]: selective inhibitors of protein kinase CK2, and their influence on activities of different forms of human CK2, and on the cells
(
Zien P.
,
Litchfield D. W.
,
Duncan J.
,
Skierski J.
,
Bretner M.
,
Shugar D.
)
artykuł:
Immunosuppressants as novel anti-inflammatory drugs affecting MAPK signalling pathways
(
Kaminska B.
)
artykuł:
Regulatory functions of seryl-phosphorylated HPr in pathogenic bacteria
(
Deutscher J.
,
Herro R.
,
Poncet S.
)
artykuł:
Orally-active pyridopyrimidine inhibitors of transforming growth factor beta RI [ALK5] kinase. Structure and activity, in-vitro and in-vivo characterization
(
Chakravarty S.
,
Dugar S.
)
artykuł:
Designing specific inhibitors of the bacterial HPr kinase-phosphorylase
(
Nessler S.
)
artykuł:
Scanning the proteome for targets of kinase inhibitors using bi-functional receptor ligands
(
Kley N.
)
artykuł:
Mammalian histidine kinases
(
Attwood P. V.
,
Besant P. G.
)
artykuł:
Isoflavonoids and their 3' and 4'-O-substitued derivatives as inhibitors of SH2 domain of p56 protein tyrosine kinase
(
Godlewska A.
,
Augustyniak R.
,
Bodera P.
)
artykuł:
Molecular dynamics study of protein-ligand interactions
(
Kriz Z.
,
Otyepka M.
,
Bartova I.
,
Koca J.
)
artykuł:
Afs1-yeast inductor of apoptosis inhibits CK2 activity in vitro
(
Jach M.
,
Kubinski K.
,
Zielinski R.
,
Sajnaga E.
,
Szyszka R.
)
artykuł:
Implications of kinase similarity in drug discovery
(
Vieth M.
,
Sutherland J.
)
artykuł:
Analysis and characterisation of protein kinase inhibitor selectivity and function
(
Daub H.
)
artykuł:
Features and potentials ATP-site directed CK2 inhibitors
(
Pinna L. A.
)
artykuł:
The interaction between protein kinase C epsilon and focal adhesion kinase
(
Toton E.
,
Hofmann J.
,
Rybczynska M.
)
artykuł:
Exploiting structural principles to generate protein kinase inhibitors
(
Noble M.
,
Barrett P.
,
Endicott J.
,
Johnson L.
,
McDonnell J.
,
Pratt D.
,
Robertson G.
)
artykuł:
Development of specific Rho-kinase inhibitor and its clinical application
(
Tamura M.
,
Hidaka H.
)
artykuł:
The RIO kinases: structural studies of a family of atypical protein kinases required for ribosome biogenesis and cell cycle progression
(
LaRonde-LeBlanc N.
,
Wlodawer A.
)
artykuł:
Involvement of the small protein tyrosine phosphatases TC-PTP and PTP1b signal transduction in diseases; from diabetes, obesity to cell cycle and cancer
(
Tremblay M. L.
)
artykuł:
Cyclin-dependent kinase inhibitor olomoucine II interacts with CDK2 and CDK9
(
Krystof V.
,
Orsag M.
,
Paprskarova M.
,
Muller P.
,
Vojtesek B.
,
Strnad M.
)
artykuł:
Alternative binding modes of proline-rich peptides binding to the GYF domain
(
Gu W.
,
Kofler M.
,
Antes I.
,
Freund C.
,
Helms V.
)
artykuł:
mTOR and p70 S6K phosphorylation by insulin plus rapamycin in HepG2 cells with and without overexpression of constitutively active Akt-PKB
(
Varma S.
,
Gupta D.
,
Khandelwal R. L.
)
artykuł:
Navigating cross-kinase selectivity space
(
Aronov A. M.
,
McClain B.
,
Caron P. R.
,
Murcko M. A.
)
artykuł:
Dynamics of signalling by PKA
(
Taylor S. S.
,
Vigil D.
,
Blumenthal D.
,
Trewhella J.
,
Kim C.
,
Anand G.
,
Johnson D.
,
Yang J.
)
artykuł:
Prediction of substrate specificities of protein kinases
(
Kobe B.
,
Brinkworth R. I.
)
artykuł:
ATP-noncompetitive inhibitors of the c-Jun N-terminal kinase [JNK] subfamily - what can they offer?
(
Bogoyevitch M. A.
,
Barr R. K.
)
artykuł:
Malaria parasite transmission to the mosquito is regulated by unusual protein kinases with stage-specific essential functions
(
Billker O.
,
Doerig C.
,
Tewari R.
,
Siden-Kiamos I.
,
Moon R.
,
Dorin D.
)
artykuł:
Effect of trichostatin a on transcription of selected signal molecule genes in Jurkat T cells
(
Januchowski R.
,
Jagodzinski P. P.
)
artykuł:
Diacylglycerol signalling: targeting protein kinase C isozymes and 'non-kinase' diacylglycerol effectors
(
Kazanietz M. G.
)
artykuł:
Domain truncation, point mutation, and surrogation for structure based kinase inhibitor design
(
Breitenlechner C. B.
,
Huber R.
,
Bossemeyer D.
,
Gassel M.
,
Masjost B.
,
Engh R. A.
)
artykuł:
Baker's yeast as a tool for the development of antifungal kinase inhibitors - targeting protein kinase C and the cell integrity pathway
(
Heinisch J. J.
)
artykuł:
Insulin-like growth factor-1 initiates a negative feed back mechanism by JNK activated SHP1 to regulate proliferation of breast cancer cells
(
Amin S.
,
Kumar A.
,
Lee J.
,
Kozlowski M.
)
artykuł:
Protein kinase structure and function analysis with chemical tools
(
Shen K.
,
Hines A. C.
,
Schwarzer D.
,
Paumi K. P.
,
Cole P. A.
)
artykuł:
Protein kinases of parasitic Protozoa and their host cells: targets for chemotherapeutic intervention?
(
Doerig C.
)
artykuł:
IP6 modulates interleukin-8 secretion in colon epithelial cells by influencing various signalling pathways
(
Weglarz L.
,
Wawszczyk J.
,
Orchel A.
,
Dzierzewicz Z.
)
artykuł:
Dissecting the functions of protein tyrosine phosphatases using chemical approaches
(
Zhang Z. Y.
)
artykuł:
Molecular dynamics simulations of phospholamban: effects of membrane, phosphorylation and aggregation
(
Houndonougbo Y.
,
Jas G. S.
,
Kuczera K.
)
artykuł:
Mechanism of inhibition of the protein kinase C by nonstructure protein 3 of hepatitis C virus
(
Hartjen P.
,
Reinholz M.
,
Baier A.
,
Borowski P.
)
artykuł:
A novel non-catalytic inhibitory mechanism employed by the CSK-homologous kinase [CHK] to inactivate SRC-family protein kinases
(
Cheng H. C.
,
Chong Y. P.
,
Mulhern T.
)
artykuł:
Screening ERK2 protein and peptide associations by fluorescence anisotropy: insights into ERK2 function and regulation by protein-protein interactions
(
Callaway K.
,
Rainey M.
,
Dalby K. N.
)
rozwiń roczniki
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