Can the Rosa canina plant be used against alkylating agents as a radical scavenger?

• Autorzy: Kizilet H. , Kasimoglu C. , Uysal H.
• Języki publikacji: EN

Abstrakty

EN

In this study we used the somatic mutation and recombination test (SMART) in Drosophila melanogaster to evaluate the genotoxicity of ethyl methanesulfonate (EMS) and the effect of Rosa canina L. ethanol extract (RCeta) on the genotoxicity of EMS. Application groups were prepared as Drosophila instant medium (DIM), including only 1ppm EMS and different concentrations (1, 2, and 4ppm) of RCeta were added to DIM, including 1 ppm EMS. As a result of our study, statistically significant genotoxic effects of EMS (P<0.05) were removed by RCeta. A particularly positive genotoxic effect of EMS has become inconclusive/ negative efficacy in both wing phenotypes on 2 and 4 ppm EMS+RCeta application groups.

Słowa kluczowe

EN

plant; alkylating agent; radical scavenger; Rosa canina; Drosophila melanogaster; somatic mutation and recombination test; SMART zob.somatic mutation and recombination test; genotoxicity; antigenotoxicity; ethyl methanesulfonate zob.ethyl methanesulphonate; ethyl methanesulphonate

• Wydawca: -
• Czasopismo: Polish Journal of Environmental Studies
• Rocznik: 2013
• Tom: 22
• Numer: 4
• Opis fizyczny: p.1263-1267,fig.,ref.

Twórcy

autor

Kizilet H.

• Institute of Science, Ataturk University, 25240 Erzurum, Turkey

autor

Kasimoglu C.

• Institute of Science, Ataturk University, 25240 Erzurum, Turkey

autor

Uysal H.

• Department of Biology, Faculty of Science, Ataturk University, 25240 Erzurum, Turkey

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