Assessment of the performance of five malaria rapid diagnostic tests in health facilities in Abidjan (Côte d’Ivoire)

• Autorzy: Konate-Toure A. , Bedia-Tanoh V.A. , Kassi F.K. , Vanga-Bosson H. , Angora E.K. , Kone E.G.M. , Miezan S.A.J. , Djohan V. , Barro-Kiki P. , Menan H.E.I. , Yavo W.
• Języki publikacji: EN

Abstrakty

EN

Regular monitoring of malaria rapid diagnostic tests (RDTs) for the management of uncomplicated malaria in healthcare facilities is a key factor in improving diagnostic quality and ensuring better case management. This study aimed to assess the performance of five RDTs (Standard Q Malaria P.f Ag and Standard Q Malaria P.f/Pan (SD Biosensor, Korea), One Step Malaria HRP2/pLDH (P.f/Pan) (Guangzhou Wondfo Biotech Co., Ltd., China), Malaria Pf/Pan (B&O Pharm, France), and Malaria test P.f/pan (Das Labor, Germany)) in two healthcare facilities in Abidjan. This cross-sectional study was conducted between September and October 2022. Overall, 250 patients suffering from uncomplicated malaria were included with a predominance of female patients (56.6%). The mean age was 22.3 years (SD = 20.6; range, 0.17–73). Of the patients tested, forty-six (46) tested positive for thick smears, reflecting a prevalence of 18.5%. Plasmodium falciparum was the most commonly detected species (93.5%). The geometric mean parasitemia was 6,111.80 parasites/μl (SD = 80,026.93) (range: 116–412461). The sensitivity ranged from 95.24% to 95.65%, whereas the specificity ranged from 93.07 to 94.09% for all five tests evaluated. The false positive rate of the tests was less than 10%. No invalid test results were reported. Two-thirds of P. malariae cases detected by microscopy showed also positive results with all the RDTs. All five RDTs showed 100% sensitivity at low parasitemia levels (< 1,000 parasites/μl blood) including three cases of parasites < 200 parasites/μl blood. This study demonstrated the importance of monitoring the performance of RDTs in clinical samples.

• Wydawca: -
• Czasopismo: Annals of Parasitology
• Rocznik: 2024
• Tom: 70
• Numer: 2
• Opis fizyczny: p.81-90,ref.

Twórcy

autor

Konate-Toure A.

• Department of Parasitology, Mycology, Animal Biology and Zoology, Felix Houphouët-Boigny University, BPV 34, Abidjan, Côte d’Ivoire
• Malaria Research and Control Centre/National Public Health Institute, BPV 47, Abidjan, Côte d’Ivoire

autor

Bedia-Tanoh V.A.

• Department of Parasitology, Mycology, Animal Biology and Zoology, Felix Houphouët-Boigny University, BPV 34, Abidjan, Côte d’Ivoire
• Malaria Research and Control Centre/National Public Health Institute, BPV 47, Abidjan, Côte d’Ivoire

autor

Kassi F.K.

• Department of Parasitology, Mycology, Animal Biology and Zoology, Felix Houphouët-Boigny University, BPV 34, Abidjan, Côte d’Ivoire
• Laboratory of Parasitology and Mycology of the Diagnosis and Research Centre on AIDS and the Others Infectious Diseases/Teaching Hospital of Treichville, 01 BPV 13, Abidjan, Cote d’Ivoire

autor

Vanga-Bosson H.

• Department of Parasitology, Mycology, Animal Biology and Zoology, Felix Houphouët-Boigny University, BPV 34, Abidjan, Côte d’Ivoire

autor

Angora E.K.

• Department of Parasitology, Mycology, Animal Biology and Zoology, Felix Houphouët-Boigny University, BPV 34, Abidjan, Côte d’Ivoire

autor

Kone E.G.M.

• Department of Parasitology, Mycology, Animal Biology and Zoology, Felix Houphouët-Boigny University, BPV 34, Abidjan, Côte d’Ivoire
• Laboratory of Parasitology and Mycology of the Diagnosis and Research Centre on AIDS and the Others Infectious Diseases/Teaching Hospital of Treichville, 01 BPV 13, Abidjan, Cote d’Ivoire

autor

Miezan S.A.J.

• Department of Parasitology, Mycology, Animal Biology and Zoology, Felix Houphouët-Boigny University, BPV 34, Abidjan, Côte d’Ivoire

autor

Djohan V.

• Department of Parasitology, Mycology, Animal Biology and Zoology, Felix Houphouët-Boigny University, BPV 34, Abidjan, Côte d’Ivoire

autor

Barro-Kiki P.

• Department of Parasitology, Mycology, Animal Biology and Zoology, Felix Houphouët-Boigny University, BPV 34, Abidjan, Côte d’Ivoire

autor

Menan H.E.I.

• Department of Parasitology, Mycology, Animal Biology and Zoology, Felix Houphouët-Boigny University, BPV 34, Abidjan, Côte d’Ivoire
• Laboratory of Parasitology and Mycology of the Diagnosis and Research Centre on AIDS and the Others Infectious Diseases/Teaching Hospital of Treichville, 01 BPV 13, Abidjan, Cote d’Ivoire

autor

Yavo W.

• Department of Parasitology, Mycology, Animal Biology and Zoology, Felix Houphouët-Boigny University, BPV 34, Abidjan, Côte d’Ivoire
• Malaria Research and Control Centre/National Public Health Institute, BPV 47, Abidjan, Côte d’Ivoire

Identyfikatory

DOI

10.17420/ap7002.525