Evaluation of in-feed larch sawdust anti-inflammatory effect in sows

• Autorzy: Tzika E.D. , Tassis P.D. , Papatsiros V.G. , Pferschy-Wenzig E.M. , Siochu A. , Bauer R. , Alexopoulos C. , Kyriakis S.C. , Franz C.
• Języki publikacji: EN

Abstrakty

EN

The study aimed to investigate the possible anti-inflammatory activity of larch sawdust as feed supplement in lactating sows’ diet and its possible effect on the prevalence of Postpartum Dysgalactia Syndrome under field conditions. In a Greek farrow-to-finish pig farm, fifteen sows were randomly and equally allocated to a negative control group (NC group), a positive control group (PC group), and a treatment group (LT group). The animals of the first two groups received 99% basic diet and 1% corn starch, while LT group animals received 99% basic diet and 1% larch sawdust. The whole trial period lasted 35 days (7 days prior to farrow – day of weaning). At parturition day, animals of the PC group received 2 ml of an anti-inflammatory drug intramuscularly (meloxicam, Metacam®, Boehringer Ingelheim Vetmedica), while the animals of both other groups, received 2 ml of normal saline. Results showed insignificant differences among experimental groups for parameters such as post-partum rectal temperature and piglets performance. On the contrary, a significant increase of mean milk lactation index was observed in LT and PC groups on the 4th day of lactation period, when compared with NC group (p=0.014). Additionally, mean IL-6 concentrations in blood in the LT group showed a tendency for reduction when compared with those found in NC, and insignificant difference (p>0.05) when compared with those observed in PC group 24 hours postpartum. Moreover, the respective TNFα mean level in the LT group at 24 and 72 hours after parturition was similar to that found in PC group, respectively) and significantly lower than that determined in the NC group (p=0.003, p=0.024. The results suggest a possible anti-inflammatory effect of larch sawdust in sows.

• Wydawca: -
• Czasopismo: Polish Journal of Veterinary Sciences
• Rocznik: 2017
• Tom: 20
• Numer: 2
• Opis fizyczny: p.321-327,ref.

Twórcy

autor

Tzika E.D.

• Farm Animals Clinic, School of Veterinary Medicine, Aristotle University of Thessaloniki, St. Voutyra 11, 54627, Thessaloniki, Greece

autor

Tassis P.D.

• Farm Animals Clinic, School of Veterinary Medicine, Aristotle University of Thessaloniki, St. Voutyra 11, 54627, Thessaloniki, Greece

autor

Papatsiros V.G.

• Clinic of Medicine, Faculty of Veterinary Medicine, University of Thessaly, Trikalon str 224, GR 43100, Karditsa, Greece

autor

Pferschy-Wenzig E.M.

• Department of Pharmacognosy, Institute of Pharmaceutical Sciences, Karl-Franzens-Universitat, Universitatsplatz 4/I, A-8010 Graz, Austria

autor

Siochu A.

• Microbiologist, Kazazi St 31,55133 Kalamaria, Thessaloniki, Greece

autor

Bauer R.

• Department of Pharmacognosy, Institute of Pharmaceutical Sciences, Karl-Franzens-Universitat, Universitatsplatz 4/I, A-8010 Graz, Austria

autor

Alexopoulos C.

• Farm Animals Clinic, School of Veterinary Medicine, Aristotle University of Thessaloniki, St. Voutyra 11, 54627, Thessaloniki, Greece

autor

Kyriakis S.C.

• Farm Animals Clinic, School of Veterinary Medicine, Aristotle University of Thessaloniki, St. Voutyra 11, 54627, Thessaloniki, Greece

autor

Franz C.

• Farm Animals Clinic, School of Veterinary Medicine, Aristotle University of Thessaloniki, St. Voutyra 11, 54627, Thessaloniki, Greece

Bibliografia

• Daza A, Rioperez J, Centeno C (2004) Changes in the composition of sows’ milk between days 5 to 26 of lactation. Span J Agr Res 2: 333-336.
• Farinacci M, Colitti M, Sgorlon S, Stefanon B (2008) Immunomodulatory activity of plant residues on ovine neutrophils. Vet Immunol Immunopathol 126: 54-63.
• Grieshop CM, Flickinger EA, Fahey GC Jr (2002) Oral administration of arabinogalactan affects immune status and fecal microbial populations in dogs. J Nutr 132: 478-482.
• Hagmuller W, Jugl-Chizzola M, Zitterl-Eglseer K, Gabler C, Spergser J, Chizzola R, Franz C (2006) The use of Thymi herba as feed additive (0.1%, 0.5%, 1.0%) in weanling piglets with assessment of the shedding of haemolysing E. coli and the detection of thymol in the blood plasma. Berl Munch Tierarztl Wochenschr 119: 50-54.
• Hoy S (2003) Investigations on the effects of puerperal diseases in sows on the fertility. Arch Tierz 46: 341-346.
• Jacela JY, DeRouchey JM, Tokach MD, Goodband RD, Nelssen JL, Renter DG, Dritz SS (2010) Feed additives for swine: Fact sheets – flavors and mold inhibitors, mycotoxin binders, and antioxidants. J Swine Health Prod 18: 27-32.
• Kim LS, Waters RF, Burkholder PM (2002) Immunological activity of larch arabinogalactan and Echinacea: a preliminary, randomized, double-blind, placebo-controlled trial. Altern Med Rev 7: 138-149.
• Klopfenstein C, Farmer C, Martineau GP (2006) Diseases of the mammary glands and lactation problems. In: Straw BE, Zimmermann JJ, D’Allaire S, Taylor DJ (eds) Diseases of swine, 9th ed., Iowa State University Press, Ames, pp 833-860.
• Madec F, Leon E (1992) Farrowing disorders in the sow: a field study. J Vet Med A 39: 433-444.
• Maes D, Papadopoulos G, Cools A, Janssens GPJ (2010) Postpartum dysgalactia in sows: pathophysiology and risk factors. Tierarztl Prax 38 (Suppl 1): S15-S20.
• Martineau GP, Farmer C, Peltoniemi O (2012) Mammary system. In: Zimmerman JJ, Karriker LA, Ramirez A, Schwartz KJ, Stevenson GW (eds) Diseases of Swine. 10th ed., Wiley-Blackwell, West Sussex, pp 270-293.
• Martineau GP, Le Treut Y, Guillou D, Waret-Szkuta A (2013) Postpartum dysgalactia syndrome: A simple change in homeorhesis? J Swine Health Prod 21: 85-93.
• Martinez D (1998) Larix. In: Blaschek W, Haensel R, Keller K, Reichling J, Rimpler H, Schneider G (eds) Hagers Handbuch der Pharmazeutischen Praxis 5 Ausgabe Vol. 3. Springer Verlag, Berlin, pp 38-43.
• Mirko CP, Bilkei G (2004) Acute phase proteins, serum cortisol and preweaning litter performance in sows suffering from periparturient disease. Acta Vet (Beograd) 54: 153-161.
• Monograph (2000) Larch Arabinogalactan. Altern Med Rev 5: 463-466.
• Papadopoulos GA, Vanderhaeghe C, Janssens GPJ, Dewulf J, Maes DG (2010) Risk factors associated with postpartum dysgalactia syndrome in sows. Vet J 184: 167-171.
• Persson A, Pedersen E, Göransson L, Kuhl W (1989) A long term study on the health status and performance of sows on different feed allowances during late pregnancy. Clinical observations with special reference to agalactia postpartum. Acta Vet Scand 30: 9-17.
• Pferschy-Wenzig EM, Kunert O, Presser A, Bauer R (2008) In vitro anti-inflammatory activity of larch (Larix decidua L.) sawdust. J Agric Food Chem 56: 11688-11693.
• Pietarinen SP, Willfor SM, Ahotupa MO, Hemming JE, Holmbom BR (2006) Knotwood and bark extracts: strong antioxidants from waste materials. J Wood Sci 52: 436-444.
• Reiner G, Hertrampf B, Richard HR (2009) Dysgalactia in the sow post partum – a review with special emphasis on pathogenesis. Tierarztl Prax 37: 305-318.
• Riollet C, Rainard P, Poutrel B (2000) Differential induction of complement fragment C5a and inflammatory cytokines during intramammary infections with Escherichia coli and Staphylococcus aureus. Clin Diagn Lab Immunol 7: 161-167.
• Robinson RR, Feirtag J, Slavin JL (2001) Effects of dietary arabinogalactan on gastrointestinal and blood parameters in healthy human subjects. J Am Coll Nutr 20: 279-285.
• Stefanon B, Sgorlon S, De Moro G, Asquini E (2009) Action of larch bark in the regulation of cortisol induced stress in sheep. Ital J Anim Sci 8 (Suppl. 2): 162-164.
• Szczubiał M, Urban-Chmiel R (2008) Tumour necrosis factor-α and interleukin-6 concentration in the serum of sows with the MMA syndrome. Bull Vet Inst Pulawy 52: 267-270.
• Van Krimpen MM, Binnendijk GP, Borgsteede FH, Gaasenbeek CP (2010) Anthelmintic effects of phytogenic feed additives in Ascaris suum inoculated pigs. Vet Parasitol 168: 269-277.
• Wang JF, Wang M, Ma GL, Jiao LG, Zhou XY, Lindberg JE (2006) The influence of intramammary lipopolysaccharide infusion on serum Ca, P, vitamin D, cytokines and cortisol concentrations in lactating sows. J Vet Med A 53: 113-118.
• Zhu Y, Berg M, Fossum C, Magnusson U (2007) Proinflammatory cytokine mRNA expression in mammary tissue of sows following intramammary inoculation with Escherichia coli. Vet Immunol Immunopathol 116: 98-103.
• Zhu Y, Magnusson U, Fossum C, Berg M (2008) Escherichia coli inoculation of porcine mammary glands affects local mRNA expression of Toll-like receptors and regulatory cytokines. Vet Immunol Immunopathol 125: 182-189.

Identyfikatory

DOI

10.1515/pjvs-2017-0039