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2012 | 34 | 2 |

Tytuł artykułu

Advances in study of ginsenoside biosynthesis pathway in Panax ginseng C. A. Meyer

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
Panax ginseng C. A. Meyer is one of the important nutraceutical and medicinal plants, which is used worldwide. Until now, ginseng has been reported to contain saponins, antioxidants, peptides, polysaccharides, fatty acids, vitamins, alkaloids, lignans, and flavonoids. The saponins, known as ginsenosides, are widely believed to be the major bioactive compounds of ginseng. In this article, ginsenoside biosynthesis pathway and key enzymes regulation are also described. This review provides a reference for improving ginsenoside contents through regulation of ginsenoside biosynthesis pathway.

Słowa kluczowe

Wydawca

-

Rocznik

Tom

34

Numer

2

Opis fizyczny

p.397-403,fig.,ref.

Twórcy

autor
  • School of Pharmaceutical Science and Technology, Tianjin University, 300072 Tianjin, China
  • Institute of Biological Enginneering of Traditional Chinese Medicine, Tianjin University of Science and Technology, 300457 Tianjin, China
autor
  • School of Pharmaceutical Science and Technology, Tianjin University, 300072 Tianjin, China
  • Institute of Biological Enginneering of Traditional Chinese Medicine, Tianjin University of Science and Technology, 300457 Tianjin, China
autor
  • Tianjin University of Traditional Chinese Medicine, 300193 Tianjin, China
autor
  • Institute of Biological Enginneering of Traditional Chinese Medicine, Tianjin University of Science and Technology, 300457 Tianjin, China
autor
  • Institute of Biological Enginneering of Traditional Chinese Medicine, Tianjin University of Science and Technology, 300457 Tianjin, China
autor
  • Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, 100700 Beijing, China

Bibliografia

  • Jeong CS, Chakrabarty D, Hahn EJ, Lee HL, Paek KY (2006) Effects of oxygen, carbon dioxide and ethylene on growth and bioactive compound production in bioreactor culture of ginseng adventitious roots. Biochem Eng J 27:252–263
  • Jorg B, Gilbert MG, Rodney C (1998) Plant terpenoid synthases: molecular biology and phylogenetic analysis. Proc Natl Acad Sci USA 4:4126–4133
  • Jung DY, Lee OR, Kim YJ, Lee JH, Pulla RK, Sathiyaraj G, Shim JS, Yang DC (2010) Molecular characterization of a cysteine proteinase inhibitor, PgCPI, from Panax ginseng C. A. Meyer. Acta Physiol Plant doi:10.1007/s11738-010-0485-y
  • Kim JH, Chang EJ, Oh HI (2005) Saponin production in submerged adventitious root culture of Panax ginseng as affected by culture conditions and elicitors. As Pac J Mol Biol Biotechnol 13(2):87–91
  • Kim YJ, Shim JS, Krishna PR, Kim SY, In JG, Kim MK, Yang DC (2008) Isolation and characterization of a glutaredoxin gene from Panax ginseng C. A. Meyer. Plant Mol Biol Rep 26:335–349
  • Kim OT, Bang KW, Kim YC, Hyun DY, Kim MY, Cha SW (2009) Upregulation of ginsenoside and gene expression related to triterpene biosynthesis in ginseng hairy root cultures elicited by methyl jasmonate. Plant Cell Tissue Organ Cult 98:25–33
  • Kima SJ, Murthy HN, Hahn EJ, Lee HL, Paek KY (2007) Parameters affecting the extraction of ginsenosides from the adventitious roots of ginseng (Panax ginseng C.A. Meyer). Sep Purif Technol 56:401–406
  • Lee JH, Kim YJ, Jeong DY, Sathiyaraj G, Pulla RK, Shim JS, In JG, Yang DC (2010) Isolation and characterization of a Glutamate decarboxylase (GAD) gene and their differential expression in response to abiotic stresses from Panax ginseng C. A. Meyer. Mol Biol Rep. doi:10.1007/s11033-009-9937-0
  • Nelson DR, Mang R, Alam M, Schuler MA (2008) Comparison of cytochrome P450 genes from six plant genomes. Trop Plant Biol 1:216–235
  • Paek KY, Chakrabarty D, Hahn EJ (2005) Application of bioreactor systems for large scale production of horticultural and medicinal plants. Plant Cell Tissue Organ Cult 81:287–300
  • Parvin S, Kim YJ, Pulla RK, Sathiyamoorthy S, Miah MG, Kim YJ, Wasnik NG, Yang DC (2010) Identification and characterization of spermidine synthase gene from Panax ginseng. Mol Biol Rep 37:923–932
  • Pulla RK, Lee OR, In JG, Parvin S, Kim YJ, Shim JS, Sun H, Kim YJ, Senthil K, Yang DC (2010) Identification and characterization of class I chitinase in Panax ginseng C. A. Meyer. Mol Biol Rep. doi:10.1007/s11033-010-0082-6
  • Pulla RK, Kim YJ, Parvin S, Shim JS, Lee JH, Kim YJ, In JG, Senthi KS, Yang DC (2009) Isolation of S-adenosyl-L-methionine synthetase gene from Panax ginseng C. A. Meyer and analysis of its response to abiotic stresses. Physiol Mol Biol Plant 15(3):267–275
  • Purey M, Kim YJ, Kim MK, Pulla RK, Yang DC (2010) Isolation of a novel catalase (Cat1) gene from Panax ginseng and analysis of the response of this gene to various stresses. Plant Physiol Biochem 48:451–460
  • Sathiyamoorthy S, In JG, Gayathri S, Kim YJ, Yang DC (2010) Generation and gene ontology based analysis of expressed sequence tags (EST) from a Panax ginseng C. A. Meyer roots. Mol Biol Rep. doi:10.1007/s11033-009-9938-z
  • Sathiyaraj G, Srinivasan S, Subramanium S, Kim YJ, Kim YJ, Kwon WS, Yang DC (2010) Polygalacturonase inhibiting protein: isolation, developmental regulation and pathogen related expression in Panax ginseng C.A. Meyer. Mol Biol Rep. doi:10.1007/s11033-009-9936-1
  • Sun H, Kim MK, Pulla RK, Kim YJ, Yang DC (2010) Isolation and expression analysis of a novel major latex-like protein (MLP151) gene from Panax ginseng. Mol Biol Rep. doi:10.1007/s11033-009-9707-z
  • Tomohisa K (2002) Mevalonate and nonmevalonate pathways for the biosynthesis of isoprene units. Biosci Biotechnol Biochem 8:1619–1627
  • Wu J, Zhong JJ (1999) Production of ginseng and its bioactive components in plant tissue culture: current technological and applied aspects. J Biotechnol 68:89–99
  • Xu R, Fazio GC, Matsuda SP (2004) On the origins of triterpenoid skeletal diversity. Phytochemistry 65(3):261–291

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Typ dokumentu

Bibliografia

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