A note on the organization and expression of beta-defensin genes in Polish goats

• Autorzy: Bagnicka E. , Prusak B. , Kosciuczuk E. , Jarczak J. , Kaba J. , Strzalkowska N. , Jozwik A. , Czopowicz M. , Krzyzewski J. , Zwierzchowski L.
• Języki publikacji: EN

Abstrakty

EN

Nucleotide (cds) and amino acids sequences of the caprine β2-defensin genes were in silico compared to search for the sequence variation and for the LAP gene sequences in the goat genome and for the presence of LAP gene transcripts in goat tissues. The comparison of the exon sequences revealed that the first 64 amino acids are identical in both LAP and β1-defensin. However, the GBD-1 prepropeptide is shorter by 18 amino acids due to the presence of the stop codon UAA at position 209–211 in GBD-1 mRNA. The LAP gene, which was found, so far, only in Indian goat breeds, is absent in the genome of Polish dairy goats. The introns of the caprine β1- and β2-defensin genes were, for the first time, sequenced; their sequences showed 99.6 % identity, differing in six nucleotide positions.

• Wydawca: -
• Czasopismo: Journal of Applied Genetics
• Rocznik: 2013
• Tom: 54
• Numer: 1
• Opis fizyczny: p.125–127,fig.,ref.

Twórcy

autor

Bagnicka E.

• Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzebiec, Postepu 1, 05-552 Magdalenka, Poland

autor

Prusak B.

• Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzebiec, Postepu 1, 05-552 Magdalenka, Poland

autor

Kosciuczuk E.

• Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzebiec, Postepu 1, 05-552 Magdalenka, Poland

autor

Jarczak J.

• Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzebiec, Postepu 1, 05-552 Magdalenka, Poland

autor

Kaba J.

• Division of Infectious Diseases and Epidemiology, Department of Large Animal Diseases with the Clinic, Faculty of Veterinary Medicine, Warsaw University of Life Sciences, Nowoursynowska 159c, Warsaw, Poland

autor

Strzalkowska N.

• Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzebiec, Postepu 1, 05-552 Magdalenka, Poland

autor

Jozwik A.

• Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzebiec, Postepu 1, 05-552 Magdalenka, Poland

autor

Czopowicz M.

• Division of Infectious Diseases and Epidemiology, Department of Large Animal Diseases with the Clinic, Faculty of Veterinary Medicine, Warsaw University of Life Sciences, Nowoursynowska 159c, Warsaw, Poland

autor

Krzyzewski J.

• Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzebiec, Postepu 1, 05-552 Magdalenka, Poland

autor

Zwierzchowski L.

• Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzebiec, Postepu 1, 05-552 Magdalenka, Poland

Uwagi

PL

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