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2014 | 58 | 3 |

Tytuł artykułu

Effect of persistent infection of mink with Aleutian mink disease virus on reproductive failure

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
The aim of this study was to assess the impact of asymptomatic infections of mink with Aleutian mink disease virus (AMD on reproductive performance and the morphology of the internal organs. The study drew its subjects from two farms where the disease was endemic and included 450 clinically healthy female mink divided into three equal groups: two AMD positive groups and one AMD negative control group. The mink were subjected to clinical observations throughout the period of reproduction, and then for the first seven weeks after birth. Data collected during this period were evaluated using selected breeding and reproductive indices. All reproductive indices including conception rate, litter size, and litter weight at birth as well as neonatal mortality were substantially poorer. Histopathological examination revealed changes typical for AMD, particularly in the spleen, kidneys, liver, and lymph nodes. The results highlighted and proved the frequently underestimated extent of economic losses on farms where AMD is endemic yet the mink stock is apparently healthy.

Słowa kluczowe

Wydawca

-

Rocznik

Tom

58

Numer

3

Opis fizyczny

p.369-373,fig.,ref.

Twórcy

autor
  • Department of Pathology, National Veterinary Research Institute, 24-100 Pulawy, Poland
autor
  • Department of Epizootiology, Clinic of Infectious Diseases, Faculty of Veterinary Medicine, University of Life Sciences, 20-950, Lublin, Poland

Bibliografia

  • 1. Alexandersen S., Hau J., Aasted B., Poulsen O.M.: Thin-layer counter current line absorption immunoelectrophoretic analysis of antigens and antibodies to Aleutian disease virus a mink parvovirus. Electrophoresis 1985, 6, 535-538.
  • 2. Alexandersen S.: Acute interstitial pneumonia in mink kits: experimental reproduction of the disease Vet Pathol 1986, 23, 579-588.
  • 3. Alexandersen S., Storgaard T., Kamstrup N., Aasted B., Porter D.D.: Pathogenesis of Aleutian mink disease parvovirus infection: effects of suppression of antibody response on viral mRNA levels and on development of acute disease. J Virol 1994, 68, 738-749.
  • 4. Best S.M., Bloom M.E.: Pathogenesis of Aleutian mink disease parvovirus and similarities to B19 infection. J Vet Med B Infect Dis Vet Public Health 2005, 52, 331-334.
  • 5. Castelruiz Y., Blixenkrone-Moller M., Aasted B.: DNA vaccination with the Aleutian mink disease virus NSI gene confers partial protection against disease. Vaccine 2005, 23, 1225-1231.
  • 6. Cerny A., Hügin A.W., Sutter S., Heusser C.H., Bos N., Izui S., Hengartner H., Zinkernagel R.M.: Suppression of B cell development and antibody responses in mice with polyclonal rabbit and monoclonal rat anti-IgM antibodies. I. Characterization of the suppressed state. Exp Cell Biol 1985, 53, 301-313.
  • 7. Cerny A., Heusser C., Sutter S., Huegin A.W., Bazin H., Hengartner H., Zinkernagel R.M.: Generation of agammaglobulinaemic mice by prenatal and postnatal exposure to polyclonal or monoclonal anti-IgM antibodies. Scand J Immunol 1986, 24, 437-445.
  • 8. Cerny A., Sutter S., Bazin H., Hengartner H., Zinkernagel R.M.: Clearance of lymphocytic choriomeningitis virus in antibody- and B-cell-deprived mice. J Virol 1988, 62, 1803-1807.
  • 9. Cheng F., Chen A.Y., Best S.M., Bloom M.E., Pintel D., Qiu J.: The capsid proteins of aleutian mink disease virus activate caspases and are specifically cleaved during infection. J Virol 2010, 84, 2687-2696.
  • 10. Florins A., Gillet N., Asquith B., Debacq C., Jean G., Schwartz- Cornil I., Bonneau M., Burny A., Reichert M., Kettmann R., Willems L.: Spleen-dependent turnover of CD11b peripheral blood B lymphocytes in bovine leukemia virus-infected sheep. J Virol 2006, 80, 11998-12008.
  • 11. Jensen T.H., Hammer A.S., Chriél M.: Monitoring chronic infection with a field strain of Aleutian mink disease virus. Vet Microbiol. 2014, 168, 420-427.
  • 12. Porter D.D., Larsen A.E., Porter H.G.: The pathogenesis of Aleutian disease of mink. II. Enhancement of tissue lesions following the administration of a killed virus vaccine or passive antibody. J Immunol 1972, 109, 1-7.
  • 13. Porter D.D., Larsen A.E., Porter H.G.: Aleutian disease of mink. Adv Immunol 1980, 29, 261-286.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

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