Zastosowanie bakteriofagów w ukierunkowanej terapii chorób bakteryjnych ryb - badania doświadczalne

• Autorzy: Siwicki A.K. , Dastych J. , Wojcik E. , Schulz P. , Kaczorek E. , Kazun K. , Kazun B. , Lepa A. , Terech-Majewska E.

Warianty tytułu

EN

Application of bacteriophages in targeted therapy of bacterial diseases in fish - an experimental study

• Języki publikacji: PL

Abstrakty

EN

The increasing resistance of bacteria to available antibiotics constitutes one of the greatest challenges in intensive fish culture. The growing problem of chemotherapeutic resistance has revived interest in the potential use of bacterial viruses (bacteriophages) for therapy of bacterial diseases in fish. Bacteriophages are viruses specific for bacterial strains and are natural regulators of bacterial populations in waters. In the present study, we determined the influence of specific bacteriophages on mortality percentages after experimental challenges with the pathogenic bacteria Aeromonas hydrophila in rainbow trout. Healthy rainbow trout, weighing 50-100 g were used in the study. Bafador-1 with 1x108 PFU/ml or 1x109 PFU/ml concentrations of bacteriophages were used in immersion or injection at 12,24, or 48 h after experimental infections. The results showed that Bafador-1 reduced mortality after application in immersion or injection at a concentration of 1 LVm3 of water, or 0.2 ml per fish. The three experimental studies presented indicated that Bafador-1 is very effective in reducing mortality after experimental infection with the pathogenic bacteria A. hydrophila. The preliminary study showed that specific bacteriophages are very effective in specific therapy of bacterial diseases in fish.

Słowa kluczowe

PL

ryby; choroby zwierzat; choroby bakteryjne; terapia; zastosowanie; bakteriofagi; badania doswiadczalne

• Wydawca: -
• Czasopismo: Komunikaty Rybackie
• Rocznik: 2014
• Numer: 5
• Opis fizyczny: s.11-15,wykr.,bibliogr.

Twórcy

autor

Siwicki A.K.

• Zakład Patologii i Immunologii Ryb, Instytut Rybactwa Śródlądowego w Olsztynie, Olsztyn

autor

Dastych J.

• Proteon Pharmaceuticals S.A., Łódź

autor

Wojcik E.

• Proteon Pharmaceuticals S.A., Łódź

autor

Schulz P.

• Katedra Mikrobiologii, Uniwersytet Warmińsko-Mazurski w Olsztynie, Olsztyn

autor

Kaczorek E.

• Katedra Mikrobiologii, Uniwersytet Warmińsko-Mazurski w Olsztynie, Olsztyn

autor

Kazun K.

• Zakład Patologii i Immunologii Ryb, Instytut Rybactwa Śródlądowego w Olsztynie, Olsztyn

autor

Kazun B.

• Zakład Patologii i Immunologii Ryb, Instytut Rybactwa Śródlądowego w Olsztynie, Olsztyn

autor

Lepa A.

• Zakład Patologii i Immunologii Ryb, Instytut Rybactwa Śródlądowego w Olsztynie, Olsztyn

autor

Terech-Majewska E.

• Katedra Epizootiologii, Uniwersytet Warmińsko-Mazurski w Olsztynie, Olsztyn

Bibliografia

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