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2015 | 47 |

Tytuł artykułu

Studying the post-operatory and molecular modifications in the chronic pancreatitis and pancreatic cancer - The Importance of the micronutrients and pancreatic enzyme supplementation

Treść / Zawartość

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
The pancreatic cancer is a disorder with an exponentially increased incidence, especially over the last few years. Moreover, it is estimated that almost 95% of the patients with this disease are presenting to the hospital in the advanced and unresectable stages. Also, over the past few decades the development and advance of the surgical methods and techniques have improved, with the most of the operatory actions in the chronic pancreatitis and pancreatic cancer being represented by the whipple duodeno-pancreatectomy, which in fact represents the standard resection for tumors of the duodenum, as well as the hepatopancreatic ampulla of Vater, distal choledocus and the head of the pancreas. Moreover, it is important to mention that in these cases, after an extended resection and reconstruction of the upper gastrointestinal tract, the digestive physiology will be disrupted. In addition, previous studies have shown that patients can maintain a body mass index after surgery but often this will be lower than its preoperative value. Thus, considering the aforementioned aspects, in the present mini-review we were mainly interested in presenting also the relevance of the micronutrients such as iron, selenium, vitamin D and E, zinc or copper in this complicated area of research, as well as aspects regarding the correlations between immune function and micronutrients or the pancreatic enzyme supplementation.

Wydawca

-

Rocznik

Tom

47

Opis fizyczny

p.89-96,ref.

Twórcy

autor
  • University of Medicine and Pharmacy "Gr.T.Popa" Iasi, Romania
autor
  • University of Medicine and Pharmacy of Cluj, Romania
autor
  • University of Medicine and Pharmacy "Gr.T.Popa" Iasi, Romania
autor
  • University of Medicine and Pharmacy "Gr.T.Popa" Iasi, Romania
autor
  • University of Medicine and Pharmacy "Gr.T.Popa" Iasi, Romania
autor
  • "Alexandru Ioan Cuza" University, Iasi, Romania
autor
  • University of Medicine and Pharmacy of Craiova, Romania

Bibliografia

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  • [5]. T. Armstrong, F. Ruiz-Jasbon, J. SheK, C. Permert, Pancreaticoduodenectomy for periampullary neoplasia leads to specific micronutrient deficiencies, Pancreatology. 7 (2007) 37-44.
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  • [11]. M. Berger, Trace element supplementation modulates pulmonary infection rates after major burns: a double-blind, placebo-controlled trial, Am J Clin Nutr. 68 (1998) 365-371.
  • [12]. C. Braunschweig, Parenteral zinc supplementation in adult humans during the acute phase response increases the febrile response, J Nutr. 127 (1997) 70-74.
  • [13]. N. Leone, D. Courbon, P. Ducimetiere, M. Zureik, Zinc, copper, and magnesium and risks for all-cause, cancer, and cardiovascular mortality, Epidemiology. 17 (2006) 308-14.
  • [14]. D. Silverman, Risk factors for pancreatic cancer: a case-control study based on direct interviews, Teratog Carcinog Mutagen. 21 (2001) 7-25.
  • [15]. R. Williamson, Gastric emptying and enterogastric reflux after conservative and conventional pancreatoduodenectomy, Surgery. 114 (1993) 82-86.
  • [16]. M. Muller, Gastric emptying following pylorus-preserving Whipple and duodenum-preserving pancreatic head resection in patients with chronic pancreatitis, Am J Surg. 173 (1997) 257-63.
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  • [18]. J. Dominguez-Munoz, Effect of the administration schedule on the therapeutic efficacy of oral pancreatic enzyme supplements in patients with exocrine pancreatic insufficiency: a randomized, three-way crossover study. Aliment Pharmacol Ther. 21 (2005) 993-1000.

Typ dokumentu

Bibliografia

Identyfikator YADDA

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