Odporność wrodzona i preparaty ja pobudzające, ze szczególnym uwzględnieniem świń

• Autorzy: Truszczynski M. , Pejsak Z.

Warianty tytułu

EN

Innate immunity and its immunostimulants with particular reference to swine

• Języki publikacji: PL

Abstrakty

EN

The growing importance for controlling infectious diseases of swine, particularly of multifactorial etiology, by non specific immunostimulants of the innate immunity has been discussed. The necessity to extend research in this area was stressed as a consequence of the significant development of large scale production of swine, generating multifactorial diseases, and from the introduced restrictions in the use of antimicrobials. After this the innate defense mechanisms were characterized. Subsequently, mentioning anatomical and physiological barriers, the role in innate immunity of leucocytes, particularly neutrophils, mononuclear phagocytes (macrophages and monocytes), natural killer cells, defensins, complement, Toll-Like receptors and cytokines were described. The following immunostimulants used at present in veterinary medicine were mentioned: Biotropin (suspension of inactivated different bacterial species); different preparations containing Propionibacterium spp.; PG/LPS containing Propionibacterium granulosum cell walls (PG) and Escherichia coli lipopolysaccharide (LPS), Inmodulen®, containing inactivated cells of Propionibacterium granulosum and lipopolysaccharide of Escherichia coli; a preparation of the cell wall of Saccharomyces cerevisiae containing α-D-mannan and β-D-glucan; Lydium-KLP. The definition of adjuvants and their importance in the efficacy of vaccines was provided, mentioning particularly Aluminum hydroxide, oil emulsions and saponin preparations including ISCOM.

Słowa kluczowe

PL

trzoda chlewna; odpornosc zwierzat; odpornosc wrodzona; immunostymulacja; preparaty immunostymulujace; biotropina; preparat LPS-PG; preparat Inmodulen; adiuwanty

• Wydawca: -
• Czasopismo: Medycyna Weterynaryjna
• Rocznik: 2013
• Tom: 69
• Numer: 09
• Opis fizyczny: s.521-525,bibliogr.

Twórcy

autor

Truszczynski M.

• Zakład Chorób Świń, Państwowy Instytut Weterynaryjny - Państwowy Instytut Badawczy, Al.Partyzantów 57, 24-100 Puławy

autor

Pejsak Z.

• Zakład Chorób Świń, Państwowy Instytut Weterynaryjny - Państwowy Instytut Badawczy, Al.Partyzantów 57, 24-100 Puławy

Bibliografia

• 1. Adlam C., Reid D. E., Marshall A. J., Torkington P.: Chemical and biological properties of a purified lymphoreticular-stimulating fraction of Corynebacterium parvum (Propionibacterium acnes type I). J. Med. Microbiol. 1979, 12, 429-440.
• 2. Bailey M.: The mucosal immune system: recent developments and future directions in the pig. Dev. Comp. Immunol. 2009, 33, 375-383.
• 3. Browder W., Williams D., Pretus H., Olivero G., Enrichens F., Mao P., Franchello A.: Beneficial effect of enhanced macrophage function in trauma patient. Ann. Surg. 1990, 211, 605-613.
• 4. Chase C. C. L., Lunney J. K.: Immune system, [w:] Zimmerman J. J., Kariker L. A., Ramirez A., Schwartz K. J., Stevenson G. W.: Diseases of Swine. Wiley-Blackwell, Ames, Iowa, USA 2012, 227-250.
• 5. Cromwell G. L.: Antimicrobial and promicrobial agents, [w:] Lewis A. J., Southern L. L.: Swine Nutrition. CRC Press, Boca Raton, FL 2001, 2nd ed., s. 401-426.
• 6. Czech A., Grela E. R., Mokrzycka A., Pejsak Z.: Efficacy of mannanoligosaccharides additive to sows diets on colostrum, blood immunoglobulin contents and production parameters of piglets. Pol. J. Vet. Sci. 2010, 13, 525-531.
• 7. Diaz-Llano G., Smith T. K.: Effecacy of Mycosorb® in preventing the deleterious effects of grains naturally contaminated with Fusarium mycotoxins on performance and metabolism of gestating sows. Alltech’s Annual Symposium on Nutritional Biotechnoligies in the Feed and Food Industries. Poster 2005.
• 8. Dlabac V., Kawasaki N.: Mannan-binding protein-like activity in the sera of newborn piglets. Immunobiology 1994, 190, 399-410.
• 9. Ezquerra A., Revilla C., Alvarez B., Perez C., Alonso F., Dominguez J.: Porcine myelomonocytic markers and cell populations. Dev. Comp. Immunol. 2009, 33, 284-298.
• 10. Ferro A., Marca J., Navarrete E., Stipkovits L.: Effect of the combination of benzylpenicillin + dihydrostreptomycin + Inmodulen® in the treatment of enzootic pneumonia. Proc. 16th Int. Pig Vet. Soc. Congr. Melbourne, Australia 2000, 129.
• 11. Ferro A., Marca J., Navarrete E., Stipkovits L.: Effect of the combination of lincomycin + Inmodulen® for swine dysentery control. Proc. 16th Int. Pig Vet. Soc. Congr. Melbourne, Australia 2000, 124.
• 12. Gerner W., Kaser T., Saalmuller A.: Porcine T lymphocytes and NK cells - an update. Dev. Comp. Immunol. 2009, 33, 310-320.
• 13. Holland P., Ellegaard J.: In vivo effects of Corynebacterium parvum on natural cell-mediated immunity in acute myeloid leukemia patients, [w:] Herberman R. B. (ed.): NK cells and other natural effector cells. Acad. Press, New York 1982, 1285-1290.
• 14. Janiak M.: Modyfikacja nieswoistych reakcji cytotoksyczności komórkowej pod wpływem preparatu Propionibacterium granulosum KP-45. Praca habil. Wojskowy Instytut Higieny i Epidemiologii, Warszawa 1986.
• 15. Ko H. L., Roszkowski W., Jeljaszewicz J., Pulverer G.: Comparative study on the immunostimulatory potency of different Propionibacterium strains. Med. Microbiol. Immunol. 1981, 170, 1-9.
• 16. Kogan G., Kocher A.: Role of yeast cell wall polysaccharides in pig nutrition and health protection. Livestock Science 2007, 109, 161-165.
• 17. Krause A., Górska P., Ślusarczyk J.: Adiuwanty - substancje stymulujące odpowiedź immunologiczną - część I. Medycyna Rodzinna 2007, 3, 75-79.
• 18. Lee E. J., Ko E., Lee J., Rho S., Ko S., Shin M. K., Min B. I., Hong M. C., Kim S. Y., Bae H.: Ginsenoside Rg1 enhances CD4(+) T-cell activities and modulates Th1/Th2 differentiation. Int. Immunopharmacol. 2004, 4, 235-244.
• 19. Lichtenstein A., Bick A., Cantrell J., Zighelboim J.: Augmentation of NK activity by Corynebacterium parvum fractions in vivo and in vitro. Int. J. Immunopharmacol. 1983, 5, 137-144.
• 20. Lo D.-Y., Hung C.-N., Lee W.-C., Liao J.-W., Blacklaws B. A., Chen T.-H., Chien M.-S., Hsuan S.-L.: Effect of immunostimulation by detoxified E. coli lipopolysaccharide combined with inactivated Propionibacterium granulosum cells on porcine immunity. J. Vet. Med. Sci. 2009, 71, 897-903.
• 21. Majtán J., Kogan G., Kováčocá E., Biliková K., Šimúth J.: Stimulation of TNF-α release by fungal cell wall polysaccharides. Z. Naturforsch. 2005, 60c, 921-926.
• 22. Marca J., Caldentey L., Torras M., Irrure P.: Efficacy of Inmodulen® in pigs naturally infected with Mycoplasma hyopneumoniae. 14th IPVS Congress, Bologna (Italy) 1996, s. 387.
• 23. Markowska-Daniel I., Pejsak Z., Szmigielski S., Jeljaszewicz J., Pulverer G.: "Prophylaktische Anwendung von Propionibacterium avidum KP-40 bei Schweinen mit akuten experimentellen Infektionen. I. Virusinfektionen-Aujeszky'sche Krankheit und klassisches Schweinefieber". Dt. tierarztl. Wschr. 1993, 100, 4, 149-152.
• 24. Markowska-Daniel I., Pejsak Z., Szmigielski S., Jeljaszewicz J., Pulverer G.: "Adjuvant properties of Propionibacterium avidum KP-40 in vaccination against endemic viral and bacterial infections. I. Swine immunized with live attenuated Aujeszky's disease virus vaccine and experimentally infected with virulent viruses". Zentbl. Bakt. 1992, 277/4, 529-538.
• 25. Mendoza G. J. P., de Antonino E. M., Badal M. E. N., Castillo M. M., Fábrega J. C., Puig J. M.: In vitro and in vivo effects of an immunomodulator composed of Escherichia coli lipopolysaccharide and Propionibacterium granulosum-inactivated cells in pigs. J. Vet. Med. 2000, 47, 619-627.
• 26. Miguel J. C., Rodriguez-Zas S. L., Pettigrew J. E.: Efficacy of Bio-Mos® in the nursery pig diet: A meta-analysis of the performance response. J. Anim. Sci. 2003, 81 (Suppl. 1), 49 (Abstr.).
• 27. Murtaugh M. P., Johnson C. R., Xiao Z., Scamurra R. W., Zhou Y.: Species specialization in cytokine biology: Is interleukin-4 central to the TH1-TH2 paradigm in swine? Dev. Comp. Immunol. 2009, 33, 344-352.
• 28. Oh G. S., Pae H. O., Choi B. M., Seo E. A., Kim D. H., Shin M. K., Kim J. D., Kim J. B., Chung H. T.: 20(S)-Protopanaxatriol, one of ginsenoside metabolites, inhibits inducible nitric oxide synthase and cyclooxygenase-2 expressions through inactivation of nuclear factor-kappaB in RAW 264.7 macrophages stimulated with lipopolysaccharide. Cancer Letters 2004, 205, 23-29.
• 29. Pejsak Z., Dors A.: Możliwości nieswoistej immunostymulacji układu odpornościowego świń. Lecznica Dużych Zwierząt 2011, 6, 25-28.
• 30. Pintaric M., Gerner W., Saalmüller A.: Synergistic effects of IL-2, IL-12 and IL-18 on cytolytic activity, perforin expression and IFN-gamma production of porcine natural killer cells. Vet. Immunol. Immunopathol. 2008, 121, 68-82.
• 31. Pretus H. A., Ensleyu H. E., McNamee R. B., Jones E. L., Browder I. W., Williams D. L.: Isolation, physicochemical characterization and preclinical efficacy evaluation of solube scleroglucan. J. Pharmacol. Exp. Ther. 1991, 257, 500-510.
• 32. Revera E., Daggfeldt A., Hu S.: Ginseng extract in aluminium hydroxide adjuvanted vaccines improves the antibody response of pigs to porcine parvovirus and Erysipelothrix rhusiopathiae. Vet. Immunol. Immunopathol. 2003, 91, 19-27.
• 33. Rivera E., Hu S., Concha C.: Ginseng and aluminium hydroxide act synergistically as vaccine adjuvants. Vaccine 2003, 21, 1149-1157.
• 34. Rozeboom D. W., Shaw D. T., Tempelman R. J., Miguel J. C., Pettigrew J. E., Connolly A.: Effects of mannan oligosaccharide and an antimicrobial product in nursery diets on performance of pigs reared on three different farms. J. Anim. Sci. 2005, 83, 2637-2644.
• 35. Sanders M. T., Brown L. E., Deliyannis G., Pearse M. J.: ISCOM-based vaccines: the second decade. Immuno. Cell. Biol. 2005, 83, 119-128.
• 36. Singh M., O'Hagan D. T.: Recent advances in veerinary vaccine adjuvants. Int. J. Parasitol. 2003, 33, 469-478.
• 37. Šrobárová A., Kogan G., Eged Š.: Yeast polysaccharide affects fusaric acid content in maize root rot. Chem. Biodiv. 2005, 2, 1685-1690.
• 38. Uenishi H., Shinkai H.: Porcine Toll-like receptors: the front line of pathogen monitoring and possible implications for disease resistance. Dev Comp Immunol. 2009, 33, 353-361.
• 39. Williams D. L., Mueller A., Browder W.: Glucan-based macrophage stimulators. A review of their anti-infective potential. Clin. Immunother. 1996, 5, 392-399.
• 40. Wilson-Welder J. H., Torres M. P., Kipper M. J., Mallapragada S. K., Wannemuehler M. J., Narasimhan B.: Vaccine adjuvants: Current challenges and future approaches. J. Pharm. Sci. 2009, 98, 1278-1316.
• 41. Xiao Z., Trincado C. A., Murtaugh M. P.: β-Glucan enhancement of T cell IFN-γ response in swine. Vet. Immunol. Immunopathol. 2004, 102, 315-320.