Regional differences in aorta of goat (Capra hircus)

• Autorzy: Ogeng'o J.A. , Malek A. K. A. , Kiama S. G.
• Języki publikacji: EN

Abstrakty

EN

Regional differences in the aortic wall are important in explaining the physicomechanical properties and disease distribution in this artery. The goat is a suitable model for studying cardiovascular disease, but the regional features of its aorta are scarcely reported. The purpose of the study was therefore to describe the regional differences in the wall of its aorta. Sixteen healthy adult male domestic goats (capra hircus) were euthanised with intravenous sodium pentabarbitone and specimens obtained from the ascending, arch, each vertebral level of descending thoracic, and various segments of abdominal aorta. The specimens were fixed in 10% formaldehyde solution and routinely processed for paraffin embedding. Seven micron thick sections were stained with Mason’s Trichrome and Weigert Resorcin Fuchsin stains. Light microscopic examination revealed that the aortic wall consists of tunica intima comprising endothelium, subendothelial zone and internal elastic lamina, media, and adventitia. Endothelium comprises flat and round endotheliocytes. The population of round cells declines as the internal elastic lamina increases in prominence caudally. Tunica media in ascending, arch, and proximal thoracic aorta comprises two zones: namely a luminal elastic and adventitial musculo-elastic zone, in which muscle islands interrupt some elastic lamellae. These islands progressively diminish caudally until by the eleventh thoracic vertebra they are only patchy. Beyond this point and in the abdominal aorta they are absent and tunica media consists of regular concentric elastic lamellae. Tunica adventitia, on the other hand, increases in thickness and elastic fibre content caudally. Regional variations exist in all three layers of goat aorta. The nature of these differences suggests that they are related to haemodynamic factors. Furthermore, the variations may form the basis for regional differences in physicomechanical strength and disease distribution along the aorta. (Folia Morphol 2010; 69, 4: 253–257)

Słowa kluczowe

EN

regional differentiation; aorta; goat; Capra hircus; healthy animal; domestic goat; male; adult animal; artery; physicomechanical property

• Wydawca: -
• Czasopismo: Folia Morphologica
• Rocznik: 2010
• Tom: 69
• Numer: 4
• Opis fizyczny: p.253-257,fig.,ref.

Twórcy

autor

Ogeng'o J.A.

• Department of Human Anatomy, University of Nairobi, P.O.Box 00100-30197, Kenya

autor

Malek A. K. A.

• Department of Human Anatomy, University of Nairobi, Kenya

autor

Kiama S. G.

• Department of Human Anatomy, University of Nairobi, Kenya

Bibliografia

• 1. Awal MA, Matsumoto M, Nishinakagawa H (1995) Morphometrical changes of the arterial wall of main arteries from heart to the abdomino-inguinal mammary glands of rat from virgin through pregnancy, lactation and post-weaning. J Vet Med Science, 57: 251–256.
• 2. Charbon GA, Anderson MF (1989) Hepatic hemodynamics as related to blood flow through gut, spleen and pancreas. Gut, 30: 265–278.
• 3. Chiche L, Leseche G (2000) Penetrating atheromatous ulcers of the aorta. Press Med, 29: 611–618.
• 4. Cho KR, Stanson AW, Potter DD, Cherry KJ, Schaff HV, Sundt TM 3rd (2004) Penetrating atherosclerotic ulcer of the descending thoracic aorta and arch. J Thor Cardiovasc Surg, 127: 1393–1399.
• 5. Crissman RS, Pakulski LA (1984) A rapid digestive technique to expose networks of vascular elastic fibres for SEM observation. Stain Technol, 59: 171–180.
• 6. Dabanoglu I (2000) A quantitative study of the Aorta of the New Zealand Rabbit (oryctolagus cuniculus). Anat Histol Embryol, 29: 145–147.
• 7. Davies PF, Shi C, Depaola N, Helmke BP, Polacek DC (2001) Hemodynamics and the focal origin of atherosclerosis: a spatial structural, gene expression, and functional approach. Ann NY Acad Sci, 947: 7–18.
• 8. Davies PF, Zilberberg J, Helmke BP (2003) Spatial microstimuli in Endothelial mechanical signalling. Circul Res, 92: 359–370.
• 9. Dobrin PB (1984) Mechanical behaviour of vascular smooth muscle in cylindrical segments of arteries in vitro. Ann Biomed Engineer, 12: 497–510.
• 10. Farand P, Garon A, Plante GE (2007) Structure of large arteries: orientation of elastin in rabbit internal elastic lamina, and in elastic lamellae of aortic media. Microvasc Res, 73: 95–99.
• 11. Gosline JM, Shadwick RE (1996). The mechanical properties of fin whale arteries are explained by novel connective tissue design. J Experim Biol, 199: 985–995.
• 12. Hass KS, Phillips SJ, Camerota AJ, White JV (1990) The architecture of adventitial elastin in the canine infrarenal aorta. Anat Rec, 230: 86–96.
• 13. Hoffman GS (2005) Determinants of vessel targeting in vasculitis. Ann NY Acad Scien, 1051: 332–339.
• 14. Lemson MS, Daemen MJ, Kitshaar PJ, Tordoir JH (1999) A new animal model to study intimal hyperplasia in AV fistula. J Surg Res, 85: 51–58.
• 15. Malek AKA, Ogeng’o J (2007) Regional differences in the tunica media of the aorta of the goat (capra ibex). J Anat, 210: 767.
• 16. Mello JM, Orsi AM, Padovani Cm, Matheus SMM, Eleuterio ML (2004) Structure of the aortic wall in the Guinea Pig and Rat. Braz J Morphol Scien, 21: 35–38.
• 17. Ogeng’o JA, Malek AAK, Kiama SG, Olabu BO (2009) Muscle “islands” in the tunica media of the goat thoracic aorta. J Morphol Sci; 26: 171–175.
• 18. Orsi AM, Stefanini MA, Crocci AJ, Simoes K, Ribeiro AACM (2004) Some segmental features on the structure of the aortic wall of the dog. Anat Histol Embryol, 31: 131–134.
• 19. Roach MR (1983) The pattern of elastin in the aorta and large arteries of mammals. Ciba Found Symp, 100: 37–55.
• 20. Robert L, Jacob MP, Fulop T (1995) Elastin in blood vessels. Ciba Found Symp, 192: 286–303.
• 21. Silver FH, Snowhill PB, Foran DJ (2003) Mechanical behaviour of vessel wall: a comparative study of aorta, vena cava, and carotid artery. Ann Biomed Eng, 31: 793–803.
• 22. Sokolis DP, Boudoulas H, Kavantzas NG, Kostomitsopoulos N, Agapitos EV, Karayannacos PE (2002) A morphometric study of the structural characteristics of the aorta in pigs using an image analysis method. Anat Histol Embryol, 31: 21–30.
• 23. Svendsen E (1985) Some characteristics of intimal folds in the rabbit aorta. Acta Pathol, 124: 178–180.
• 24. Tindal AR, Svendsen E (1982) Intimal folds of the rabbit aorta. Acta Anat, 113: 169–177.
• 25. Wolinsky H, Glagov S (1969) Comparison of abdominal and thoracic aortic medial structure in mammals. Deviation of man from the usual pattern. Circ Res; 25: 677–686.
• 26. Zheng JW, Qiu WL, Zhang ZY, Lin GC, Zhu HG (2000) Anatomical and histologic study of the cervical vessels in goats. Shangai Kou Qiang Yi Xue, 9: 39–41.