Ocena stosowania substancji przeciwdrobnoustrojowych u świń i bydła w Polsce na podstawie badań sondażowych w 2010 roku

• Autorzy: Krasucka D. , Cybulski W. , Klimowicz A.

Warianty tytułu

EN

Evaluation of antimicrobial agents consumption in swine and cattle in Poland based on a questionnaire in 2010

• Języki publikacji: PL

Abstrakty

EN

The European Medicines Agency (EMA) obliges EU members to report of on sales/distribution of veterinary medicinal products (VMP) at a national level. In addition to this mandatory route, a research project based on a questionnaire of 109 practitioner veterinarians representing all regions of Poland has been carried out. The results of statistical analysis of antimicrobial agents used by the probed veterinarians to treat swine and cattle have been completed for 2010. The data were expressed according to recommendations of EMA as the weight mass of pharmacologically active substances within the antibiotic groups. The responder reports placed the tetracycline group as the most frequent agent used in the swine treatments; weight amounts scored 49.1% of total antimicrobials. The penicillin group amounted to 25.7%, followed by macrolides (8.1%) and sulfonamides (5.9%). Aminoglicosides, pleuromutylines and fluoroquinolones usage numbered 3.0%, 2.95% and 2.8%, respectively. Whereas in cattle the prevalence was of penicillins (35.2%), followed by sulfonamides (33.5%), tetracycline (15.9%), aminoglicoside (9.6%), fluoroquinolone (3.5%) and macrolide (1.5%) were recorded. A similar trend of antimicrobial agents consumption was observed in statistics from the countries neighboring Poland in the south; however, when compared to Scandinavia countries it differed. Analysis of the data for antimicrobial agents make it possible to evaluate the prudent use of antibiotics and sulfonamides in Poland. In case of fluoroquinolone, the low figures situated this group in the second line order of antibiotics administered to swine, since they were used as the fifth group of antimicrobials in cattle.

Słowa kluczowe

PL

produkty lecznicze; substancje przeciwdrobnoustrojowe; leki przeciwdrobnoustrojowe; antybiotyki; sulfonamidy; stosowanie; bydlo; trzoda chlewna; rok 2010; Polska; badania sondazowe

• Wydawca: -
• Czasopismo: Medycyna Weterynaryjna
• Rocznik: 2012
• Tom: 68
• Numer: 02
• Opis fizyczny: s.106-109,rys.,bibliogr.

Twórcy

autor

Krasucka D.

• Zakład Farmacji Weterynaryjnej, Państwowy Instytut Weterynaryjny - Państwowy Instytut Badawczy, Al.Partyzantów 57, 24-100 Puławy

autor

Cybulski W.

autor

Klimowicz A.

Bibliografia

• 1.Anon.: Draft agenda of Meeting on monitoring of sales of veterinary antimicrobial agents in Europe. 25 November 2009, EMEA.
• 2.Anon.: Draft agenda of Meeting with stakeholders on monitoring sales of veterinary antimicrobial agents in Europe. 28 September 2010, EMA/271500/2010.
• 3.Anon.: Komisja Europejska Dyrekcja Generalna ds. Zdrowia i Konsumentów, Ocena przepisów prawnych UE w dziedzinie pasz leczniczych. Raport Końcowy. Bruksela 2010 r.
• 4.Anon.: Trends in the sales of veterinary antimicrobial agents in nine European countries. 15 September 2011, EMA/238630/2011.
• 5.Bednarek D.: Nowe metody terapii syndromu oddechowego bydła. Weterynaria w Terenie 2008, 1, 28-36.
• 6.Białek-Bielańska A., Kumirska J., Palavinskas R., Stepnowski P.: Optimization of multiple reaction monitoring mode for the trace analysis of veterinary sulfonamides by LC-MS/MS. Talanta 2009, 80, 947-953.
• 7.Bimazubute M., Cambier C., Vanbelle S., Chiap P., Albert A., Delporte J. P., Gustin P.: Penetration of enrofloxacin into the nasal secretions and relationship between nasal secretions and plasma enrofloxacin concentrations after intramuscular administration in healthy pigs. J. Vet. Pharmacol. Therap. 2009, 33, 183-188.
• 8.Ensink J. M., Bosch G., Van Duijkeren E.: Clinical efficacy of prophylactic administration of trimethoprim/sulfadiazine in a Streptococcus equi subsp. Zooepidemicus infection model in ponies. J. Vet. Pharmacol. Therap. 2005, 28, 45-49.
• 9.Grobbel M., Liibke-Becker A., Wieler L. H., Froyman R., Friedrichs S., Filios S.: Comparative quantification of the in vitro activity of veterinary fluoroquninolones. Vet. Microbiol. 2007, 124, 73-81.
• 10.Kools S. A. E., Moltman J. F., Knacker T.: Estimating the use of veterinary medicines in the European Union. Regul. Toxicol. Pharmacol. 2008, 50, 59-65.
• 11.Roliński Z.: Farmakologia i farmakoterapia weterynaryjna. PWRiL, Warszawa 2008, s. 380-386.
• 12.Tanigawa M., Sawada T.: Effects of subminimal inhibitory concentrations of amoxicillin against Actinobacillus pleuropneumoniae. J. Vet. Med. B 2002, 49, 513-518.