Variation of the cholesterol content in breast milk during 10 days collection at early stages of lactation

• Autorzy: Kamelska A. M. , Pietrzak-Fiecko R. , Bryl K.
• Języki publikacji: EN

Abstrakty

EN

More and more research is done concerning nutritional programming. Human milk nutrients which are consumed by infants can influence their health in later life. High level of cholesterol in human milk paradoxically lowers the cholesterol concentration in blood in adults. During the course of human lactation the cholesterol concentration decreases from 31 mg/100cm3 (colostrum) to 16 mg/100 cm3 (mature milk). According to Scopesi et al., 2002, Clin Nutr 21: 379-384, cholesterol concentration in mature milk ranged from 6.5 to 18.4 mg/100 cm3. The aim of the study was to assess the variations in breast milk cholesterol content during 10 day collection at early lactation. 48 samples of human milk were analyzed. Mean age of women was 31 years. Women were collecting samples during 10 days of an early lactation stage (1-3 months after delivery). An Attenuated Total Reflectance Fourier Transformed Infrared (FTIR-ATR) method for easy and rapid determination of cholesterol in human milk was elaborated. Cholesterol content assessed by the FTIR method ranged from 3.36 to 12.98 mg/100 cm3. Results indicate that milk cholesterol concentration during 10 consecutive days of early lactation is highly variable. Cholesterol content depends on an individual. Therefore it is suggested that not only the period of lactation but also mother's diet, age, season and place of residence are important factors determining cholesterol content.

• Wydawca: -
• Czasopismo: Acta Biochimica Polonica
• Rocznik: 2012
• Tom: 59
• Numer: 2
• Opis fizyczny: p.243-247,fig.,ref.

Twórcy

autor

Kamelska A. M.

• Chair of Physics and Biophysics, Faculty of Food Sciences, University of Warmia and Mazury in Olsztyn, Olsztyn, Poland

autor

Pietrzak-Fiecko R.

autor

Bryl K.

Bibliografia

• Adams JS, Hollis B (2002) Vitamin D: Synthesis, Metabolism, and Clinical Measurement. In Disorders of Bone and Mineral Metabolism. Coe FL, Favus MJ, eds, 159. Lippincott Williams and Wilkins. Philadelphia. 
• Agostoni C, Riva E (1998) Dietary fatty acids and cholesterol in the first 2 years of life. Prostaglandins Leukot Essent Fatty Acids 58: 33-37. 
• Alonso L, Lozada L, Fontecha J, Juirez M (1995) Determination of cholesterol in milk fat by gas chromatography with direct injection and sample saponification. Chromatographia 41: 23-28.
• Arsov Z, Quaroni L (2008) Detection of lipid phase coexistence and lipid interactions in sphingomyelin/cholesterol membranes by ATR-FTIR spectroscopy. Biochim Biophys Acta 1778: 880-889. 
• Bachman KC, Lin JH, Wilcox CJ (1976) Sensitive colorimetric determination of cholesterol in dairy products. J Assoc Off Anal Chem 59: 1146-1149.  
• Castelli WP, Anderson K, Wilson PW, Levy D (1992) Lipids and risk of coronary heart disease: the Framingham Study. Ann Epidemiol 2: 23-28. 
• Castelli WP, Garrison RJ, Wilson PW, Abbott RD, Kalousdian S, Kannel WB (1986) Incidence of coronary heart disease and lipoprotein-cholesterol levels: the Framingham Study. JAMA 256: 2835-2838. 
• Channa NA, Khand FD., Bhanger MI (2008) Analysis of human gallstones by FTIR. Malaysian J Anal Sci 12: 552-560.
• Dietschy JM, Turley SD (2004) Thematic review series: brain Lipids. Cholesterol metabolism in the central nervous system during early development and in the mature animal. J Lipid Res 45: 1375-1397.  
• Emmett PM, Rogers IS (1997) Properties of human milk and their relationship with maternal nutrition. Early Hum Dev 49 (Suppl): S7-S28. 
• Fletouris DJ, Botsoglou NA, Psomas IE, Mantis AI (1998) Rapid determination of cholesterol in milk and milk products by direct saponification and capillary gas chromatography. J Dairy Sci 81: 2833-2840. 
• Hamosh M. (1988) Fat needs for term and preterm infants. In: Nutrition during infancy. Tsang RC, Nichols BL, eds, pp 133-159. Hanley & Belfus Inc., Philadelphia. 
• Harvey et al. (2005) Biochemistry. 3rd edn, 235-238. Baltimore: Lippincott.
• Kallio MJ, Siimes MA, Perheentupa J, Salmenpera LS, Miettinen TA (1989) Cholesterol and its precursors in human milk during prolonged exclusive breast-feeding. Am J Clin Nutr 50: 782-785. 
• Kamelska AM, Pietrzak-Fiećko R, Bryl K (2010) Analysis of selected infant formula samples including cholesterol determination by FTIR-ATR method. In: The quality and health promoting qualities of food. Wojtatowicz M, Kawa-Rygielska J, eds, pp 87-99. Wroclaw University of Environmental and Life Sciences Publishing House, Wroclaw, Poland.
• Kamelska AM, Pietrzak-Fiećko R, Bryl K (2011) Cholesterol content as an infant formulas quality determinant. University of Economics in Poznan Scientific Papers 196: 38-45.
• Koletzko B (2005) Developmental origins of adult disease: Barker's or Dörner's hypothesis? Am J Hum Biol 17: 381-382. 
• Koletzko B, Akerblom H, Dodds PF, Ashwell M (Hrsg.) (2005) Early nutrition and its later consequences: New opportunities. New York, Springer Publishers. Adv Exp Med Biol 569: 1-237. 
• Kowalewska-Kantecka B (2007) Breastfeeding- the gold standard of infant nutrition. Contemporary Pediatrics. Gastroenterology, Hepathology and Child Nutr 9: 65-68.
• Lai YW, Kemsley EK, Wilson RH (1995) Quantitative analysis of potential adulterant of extra virgin olive oil using IR spectroscopy. Food Chem 53: 95-98.
• Owen CG, Whincup PH, Kaye SJ, Martin RM, Smith GD, Cook DG, et al. (2008) Does initial breastfeeding lead to lower blood cholesterol in adult life? A quantitative review of the evidence. Am J Clin Nutr 88: 305-314.  
• Paradkar M, Irudayaraj J (2002) Determination of cholesterol in dairy products using infrared techniques: FTIR spectroscopy. Int Diary Technol 55: 127-132.
• Reiser R, Sidelman Z (1972) Control of serum cholesterol homeostasis by cholesterol in the milk of the suckling rat. J Nutr 102: 1009-1016. 
• Scopesi F, Zunin P, Mazzella M, Testa M, Boggia R, Evangelisti F, Serra G (2002) 7-ketocholesterol in human and adapted milk formulas. Clin Nutr 21: 379-384. 
• Syahariza ZA, Che Man YB, Selamat J (2005) Detection of lard adulteration in cake formulation by FTIR spectroscopy, Analytical, Nutritional and Clinical Methods. Food Chem 92: 365-371.
• Talpur FN, Bhanger MI, Khuhawar MY (2006) Comparison of fatty acids and cholesterol content in the milk of Pakistani cow breeds. J Food Comp Anal 19: 698-703.

Uwagi

PL

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