Socialization assessment of TSC1 knockout mice

• Autorzy: Wiaderkiewicz J. , Barski J. J.
• Języki publikacji: EN

Abstrakty

EN

Tuberous sclerosis (TSC) is a genetic disorder, linked to the TSC1 gene and characterized by the emergence of multi-system benign tumors. Symptoms related to central nervous system disruptions include seizures, developmental delay and a varying range of behavioral disorders. These disorders can be identified by analyzing various parameters, many of which can be observed during social interactions. Cre recombinase mediated TSC1 gene knockout mice were constructed and analyzed for sociability and preference for social novelty. The test was performed in a standard threechamber sociability cage and results were obtained and analyzed using automated tracking software Ethovision XT from Noldus.

• Wydawca: -
• Czasopismo: Acta Neurobiologiae Experimentalis
• Rocznik: 2014
• Tom: 74
• Numer: 3
• Opis fizyczny: p.368

Twórcy

autor

Wiaderkiewicz J.

• Center for Experimental Medicine, Medical University of Silesia, Katowice, Poland
• Department of Physiology, Medical University of Silesia, Katowice, Poland

autor

Barski J. J.

• Center for Experimental Medicine, Medical University of Silesia, Katowice, Poland
• Department of Physiology, Medical University of Silesia, Katowice, Poland