Red kidney bean (Phaseolus vulgaris) lectin stimulation increases the number of enterochromaffin cells in the small intestine of suckling piglets

• Autorzy: Zacharko-Siembida A. , Velverde Piedra J. L. , Strzalka B. , Arciszewski M. B.
• Języki publikacji: EN

Abstrakty

EN

The quantities and distribution patterns of serotonin-immunoreactive (serotonin-IR) enterochromaffin cells (EC) were studied immunohistochemically in the small intestine of suckling piglets stimulated with red kidney bean lectin, and in non- stimulated, control animals. The co-expression patterns of serotonin with somatostatin (SOM) or corticotropin releasing-factor (CRF) were also studied. After the lectin treatment, the increased numbers of EC were noted in the duodenum of experimental animals. Lectin stimulation did not change the proportions of EC in the jejunum and ileum. In the duodenal epithelium of the lectin-stimulated piglets, the vast majority of serotonin-IR EC were distributed at the basis of crypts. After the lectin administration, the proportions of serotonin-IR/SOM-IR EC were statistically similar in all sections of the small intestine. No upregulation of CRF was found in duodenal, jejunal, and ileal EC of lectin-treated animals. The findings demonstrated that red kidney bean lectin increased the serotonin reservoir in the duodenum, and thus may be an effective stimulant of the gut maturation in suckling mammals.

• Wydawca: -
• Czasopismo: Bulletin of the Veterinary Institute in Puławy
• Rocznik: 2014
• Tom: 58
• Numer: 2
• Opis fizyczny: p.289-294,fig.,ref.

Twórcy

autor

Zacharko-Siembida A.

• Department of Animal Anatomy and Histology, Faculty of Veterinary Medicine, University of Life Sciences, 20-033 Lublin, Poland

autor

Velverde Piedra J. L.

• Sub-Department of Toxicology and Environment Protection, Faculty of Veterinary Medicine, University of Life Sciences, 20-033 Lublin, Poland

autor

Strzalka B.

• Department of Animal Anatomy and Histology, Faculty of Veterinary Medicine, University of Life Sciences, 20-033 Lublin, Poland

autor

Arciszewski M. B.

• Department of Animal Anatomy and Histology, Faculty of Veterinary Medicine, University of Life Sciences, 20-033 Lublin, Poland

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