Does the apoptotic fragmentation of DNA starts by excision of chromosomal DNA loop domains?

• Autorzy: Ioudinkova E. , Bystritsky A. , Razin S.
• Języki publikacji: EN

Abstrakty

EN

In this paper we are presenting a critical review of works demonstrating that at the early stages of apoptosis eukaryotic DNA is cleaved to large fragments the length of which is several tens of thousands of nucleotide pairs. Evidence is presented that this fragmentation proceeds in a specific fashion and that the character of the fragmentation reflects the general principle of eukaryotic genome organization into structural-functional domains.

Słowa kluczowe

EN

eukaryotic cell; genomic domain; DNA loop; apoptosis; nucleus; DNA fragmentation

• Wydawca: -
• Czasopismo: Cellular and Molecular Biology Letters
• Rocznik: 1998
• Tom: 03
• Numer: 2
• Opis fizyczny: p.103-109

Twórcy

autor

Ioudinkova E.

• Institute of Gene Biology, 34-5 Vavilov St., 117334, Moscow, Russia

autor

Bystritsky A.

autor

Razin S.

Bibliografia

• 1. Arends, M. J., Morris R. G. and Willie A. H. Am. J. Pathol. 136 (1990) 593-608.
• 2. Cohen G. M. and Duke R. C. J. Immunol. 132 (1984) 38-42.
• 3. McConkey D. J., Hartzell P., Nicotera P. and Orrenius S. FASEB J. 3 (1989) 1843-1849.
• 4. Filipski J., Leblank J., Youdale T., Sikorska M. and Walker P. R. EMBO J. 9 (1990) 1319-1327.
• 5. Schwartz D. S. and Cantor C. R. Cell 37 (1984) 67-75.
• 6. Brown D. G., Sun X. M. and Cohen G. M. J. Biol. Chem. 268 (1993) 3037-3039
• 7. Oberhammer F., Wilson G. W., Dive C., Morris I. D., Hickman J. A., Wakeling A. E., Walker P. R. and Sikorska M. EMBO J. 12 (1993) 3679-3684.
• 8. Cain K., Inayat-Hussain S. H., Wolfe J. T. and Cohen J. M. FEBS Lett. 349 (1994) 385-391.
• 9. Sun X.-M. and Cohen G. M. J. Biol. Chem. 269 (1994) 14857-14860.
• 10. Zhivotovsky B., Cedervall B., Jiang. S., Nicotera P. and Orrenius S. Biochem. Biophys. Res. Commun. 202 (1994) 120-127.
• 11. Peitsch M., Polzar B., Stefan H., Crompton T., MacDonald H. R., Mannherz H. G. and Tschopp J. EMBO J. 12 (1993) 371-377.
• 12. Peitsch M., Mannherz H. G. and Tschopp J. Trends in Cell Biol. 4 (1994) 37-41.
• 13. Pienta K. J., Getzenberg R. H. and Coffey D. S. Crit. Rev. Eukar. Gene Expres. 1 (1991) 355-385.
• 14. Getzenberg R. H., Pienta K. J., Ward W. S. and Coffey D. S. J. Cell Biochem. 47 (1991) 289-299.
• 15. Georgiev G. P., Vassetzky Y. S. and Luchnik A. N. Eur. J. Biochem. 200 (1991) 613-624.
• 16. Cook P. R. and Brazell I. A. J. Cell Sci. 19 (1975) 261-279.
• 17. Cook P. R. and Brazell I. A. J. Cell Sci. 22 (1976) 287-302.
• 18. Cook P. R. and Brazell I. A. J. Cell Sci. 22 (1976) 303-324.
• 19. Paulson J. R. and Laemmli U. K. Cell 12 (1977) 815-828.
• 20. Hancock R. and Hughes M. I. Biol. Cell 44 (1982) 201-212.
• 21. Razin S. V., Gromova I.I. and Iarovaia O. V. Int. Rev Cytol. 162B (1995) 405-448.
• 22. Razin S. V. Crit. Rev. Eukar. Gene Expres. 6 (1996) 247-269.
• 23. Hancock R. Biol. Cell 46 (1982) 105-122.
• 24. Jackson D. A., Dickenson P. and Cook P. R. EMBO J. 9 (1990) 567-571.
• 25. Weintraub H. and Groudine M. Science 73 (1976) 848-856.
• 26. Boulikas T. J. Cell Biochem. 52 (1993) 14-22.
• 27. Boulikas T. Int. Rev. Cytol. 162A (1995) 279-388.
• 28. Razin S. V., Hancock R., Iarovaia O., Westergaard O., Gromova I. and Georgiev G. P. Cold Spring Harbor Symp.Quant. Biol. 58 (1993) 25-35.
• 29. Gromova I. I., Thomson B. and Razin S. V. Proc. Natl. Acad. Sci. USA 92 (1995) 102-106.
• 30. Iarovaia O. V., Hancock R., Lagarkova M. A., Miassod R. and Razin S. V. Mol. Cell. Biol. 16 (1996) 302-308.
• 31. Razin S. V. and Gromova I. I. Bioessays 17 (1995) 443-450.
• 32. Lagarkova M. A., Iarovaia O. V. and Razin S. V. J. Biol. Chem. 270 (1995) 20239-20241.
• 33. Gromova I. I., Nielsen O. F. and Razin S. V. J. Biol. Chem. 270 (1995) 18685-18690.
• 34. Lagarkova M. A., Iarovaia O. V. and Razin S. V. Mol. Gen. Genet. 249 (1995) 253-256.