Motifs of the caldesmon family

• Autorzy: Czurylo E. A.
• Języki publikacji: EN

Abstrakty

EN

Seven highly conserved regions were found in caldesmon molecules from various sources using the multiple sequence alignment method. Their localization coincides with regions where the binding sites to other proteins were postulated. Less conserved and highly divergent regions of the sequences are described as well. These results could refine the planning of caldesmon gene manipulations and accelerate the precise localization of binding sites in the caldesmon molecule and, as a consequence, this could help to elucidate its function in smooth muscle contraction.

Słowa kluczowe

EN

caldesmon; secondary structure prediction; protein; multiple sequence alignment; smooth muscle; conserved sequence; binding site

• Wydawca: -
• Czasopismo: Acta Biochimica Polonica
• Rocznik: 2000
• Tom: 47
• Numer: 4
• Opis fizyczny: p.1019-1026,fig.,ref.

Twórcy

autor

Czurylo E. A.

• Nencki Institute of Experimental Biology, L.Pasteura 3, 02-093 Warsaw, Poland

Bibliografia

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