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2008 | 52 | 1 |

Tytuł artykułu

Pathomorphological lesions in the pancreas, kidneys, and liver of a dog with phaeochromocytoma and chronic hypoglycaemia - a case study

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
A dog (male, dachshund, aged 16.5 years) was euthanised due to hypoglycaemia, which had lasted for about eight years. Macroscopic examinations revealed bilateral tumours of the following sizes 7 cm x 5 cm x 4 cm (right) and 6 cm x 5 cm x 3.5 cm (left) in the sublumbar area. The presence of these tumours was found with an ultrasound examination performed on the dog at the age of 8 years. At that time, the tumours were only half the size. Histopathologically, the tumours were classified as phaeochromocytoma. The morphology of the liver, extensive necrotic foci and hyperplasia of connective tissue in particular, contributed to the dog's hypoglycaemia. The lesions could have developed as a result of damage to acinar cells of the pancreas and became advanced due to long-term glycocorticotherapy. In turn, originally, hypoglycaemia might have developed in the dog as a result of adrenal medulla failure induced by phaeochromocytoma.

Wydawca

-

Rocznik

Tom

52

Numer

1

Opis fizyczny

p.153-158,fig.,ref.

Twórcy

autor
  • University of Warmia and Mazury, 10-719 Olsztyn, Poland
autor
autor

Bibliografia

  • 1. Andrzejewska A.: Dynamics of the morphological lesions in liver in the course of the acute pancreatitis. Habilitation thesis. Medical University of Białystok, Białystok, 1990.
  • 2. Bouayad H., Feeney D.A., Caywood D.D., Hayden D.W.: Pheochromocytoma in dogs: 13 cases (1980-1985). J Am Vet Med Assoc 1987, 12, 1610-1615.
  • 3. Bravo E.L., Tarazi R.C., Gifford R.W. Jr., Stewart B.H.: Circulating and urinary catecholamines in pheochromocytoma. N Engl J Med 1979, 301, 682-686.
  • 4. Brown A.J., Alwood A.J., Cole S.G.: Case report. Malignant pheochromocytoma presenting as a bradyarrhythmia in a dog. J Vet Emerg Crit Care 2007, 2, 164-169.
  • 5. Chambers S., Espiner E.A., Donald R.A., Nicholls M.G.: Hypoglycemia following removal of phaeochromocytoma: case report and review of the literature. Postgrad Med J 1982, 58, 503-506.
  • 6. Fojut-Pałka B.: Hipoglikemia u zwierząt. Trzeba o niej mówić częściej. Cz. I. Magazyn Wet 2003, 12, 20-24.
  • 7. Fojut-Pałka B.: Hipoglikemia u zwierząt. Trzeba o niej mówić częściej. Cz. II. Magazyn Wet 2003, 12, 30-33.
  • 8. Heath H., Edis A.J.: Pheochromocytoma associated with hypercalcemia and ectopic secretion of calcitonin. Ann Intern Med 1979, 91, 208-210.
  • 9. Kyogoku T., Manabe T., Tobe T.: Role of ischemia in acute pancreatitis. Hemorrhagic shock converts edematous pancreatitis to hemorrhagic pancreatitis in rats. Dig Dis Sci 1992, 9, 1409-1417.
  • 10. Levis P.R., Knight D.R.: Staining methods for sectioned material. North Holland Publishing Company, Amsterdam, New York, Oxford, 1977.
  • 11. Sako T., Kitamura N., Kagawa Y., Hirayama K., Morita M., Kurosawa T., Yoshino T., Taniyama H.: Immunohistochemical evaluation of a malignant pheochromocytoma in a wolf dog. Vet Pathol 2001, 4, 447-450.
  • 12. Stenstrom G., Sjostrom K., Smith U.: Diabetes mellitus in phaeochromocytoma. Fasting blood glucose levels before and after surgery in 60 patients with phaeochromocytoma. Acta Endocrinol 1984, 106, 511-515.
  • 13. Tatić S., Havelka M., Paunović I., Bozić V., Diklic A., Brasanac D., Janković R., Jancić-Zguricas M.: Pheochromocytoma - pathohistologic and immunohistochemical aspects. Srp Arch Celok Lek 2002, 130, 7- 13.
  • 14. West J.L.: Bovine pheochromocytoma: case report and review of literature. Am J Vet Res 1975, 36, 1371-1373.
  • 15. Winnicka A.: Wartości referencyjne podstawowych badań laboratoryjnych w weterynarii. Editor SGGW, Warszawa, 1997, pp. 52-53.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

bwmeta1.element.agro-article-f41638b5-81b3-4b4f-957d-7759a6d58aa1
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