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2007 | 63 | 08 |

Tytuł artykułu

Aktualne poglady na budowe, funkcjonowanie i znaczenie receptorow glutaminianergicznych typu NMDA

Warianty tytułu

EN
Current views on the structure, molecular function and role of the glutamate receptors NMDA

Języki publikacji

PL

Abstrakty

EN
The paper reviews the terminology, molecular activity and role of the NMDA glutamate receptors. As excitatory aminoacid receptors these receptors are generally classified as ionotropic (NMDA, AMPA, KA) and metabotropic depending (mGluR₁₋₈) on whether they form ion channels or are coupled to G-proteins, respectively. Recent investigations indicated the essential role of the NMDA receptors in the nociceptive processus modulation. Recent progress has been made in the development of specific antagonists - such as MK-801, araxines, mementine, DL-AP-3, and others - for these receptors, and can siginicantly facilitate prophilaxy and therapy in different types of pain.

Wydawca

-

Rocznik

Tom

63

Numer

08

Opis fizyczny

s.896-899,rys.,bibliogr.

Twórcy

autor
  • Szkola Glowna Gospodarstwa Wiejskiego, ul.Nowoursynowska 159, 02-776 Warszawa
autor

Bibliografia

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Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

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