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2007 | 63 | 01 |

Tytuł artykułu

Krotkotrwale znieczulenie psow przy uzyciu midazolamu i ksylazyny

Warianty tytułu

EN
Short-acting anaesthesia in dogs with the use of midazolam and xylazine

Języki publikacji

PL

Abstrakty

EN
Clinical practice with small animals often requires the immediate introduction of the patient to short-acting anaesthesia. The aim of the study was the evaluation of the use of midazolam and xylazine as short-acting anaesthesia for dogs. The investigation was carried out on 27 dogs. The general anaesthesia was performed by using a mixture including: atropine 0.05 mg/kg, xylazine 1 mg/kg and midazolam 0.3 mg/kg. The drugs were administered intravenously by using one syringe at a dose dependant on the effects of the operation. Anaesthesia was evaluated testing palpebral reflex, corneal reflex, superficial sensibility and pedal reflex. Body temperature, heart rate, respiratory rate, parameters of acid-base balance and blood oxyganation were determined during anaesthesia. Intravenous administration of atropine, xylazine and midazolam at a dose dependant on the effects of the operation induce general anaesthesia lasting about 20 minutes. The anaesthesia was connected with the loss of consciousness and pain sensitivity. This kind of anaesthesia causes transient acid-base balance disturbances and respiratory depression. The method of anaesthesia used in our study provides fast induction and recovery without antagonists. The negative effect on the anaesthetised animals was minimal.

Wydawca

-

Rocznik

Tom

63

Numer

01

Opis fizyczny

s.72-74,tab.,bibliogr.

Twórcy

autor
  • Akademia Rolnicza, ul.Gleboka 30,20-612 Lublin
autor
autor
autor
autor

Bibliografia

  • 1. Aitkenhead A. R., Pepperman M. L., Willatts S. M., Coates P. D., Park G. R., Bodenham A. R., Collins C. H., Smith M. B., Ledingham I. M., Wallace P. G.: Comparison of propofol and midazolam for sedation in critically ill patients. Lancet 1989, 2, 704-709.
  • 2. Chyczewski M., Jałyński M., Brzeski W., Nowicki M., Adamiak Z., Depta A., Rychlik A.: Znieczulenie złożone z udziałem atropiny, midazolamu i propofolu w zabiegach artroskopowych u psów. Medycyna Wet. 2002, 58, 120-123.
  • 3. Ćwiek A.: Badania porównawcze na indukcją znieczulenia ogólnego u psów przy użyciu midazolamu i propofolu. Praca doktorska, AR Lublin 2005.
  • 4. Fujii Y., Toyooka H.: Midazolam versus propofol for reducing contractility of fatigued canine diaphragm. Br. J. Anaesth. 2001, 86, 879-881.
  • 5. Hall L. W., Clarke K. W.: Veterinary Anaesthesia. Bailliere Tindall, London 1991.
  • 6. Hayashi K., Nishimura R., Yamaki A., Kim H. Y., Matsunaga S., Sasaki N., Takeuchi A.: Cardiopulmonary effects of medetomidine, medetomidine-midazolam and medetomidine-midazolam-atipamezole in dogs. J. Vet. Med. Sci. 1995, 57, 99-104.
  • 7. Ilback N. G., Stalhandske T.: Cardiovascular effects of xylazine recorded with telemetry in the dog. J. Vet. Med. A. Physiol. Pathol. Clin. Med. 2003, 50, 479-483.
  • 8. Itamoto K., Hikasa Y., Sakonjyu I., Itoh H., Kakuta T., Takase K.: Anaesthetic and cardiopulmonary effects of balanced anaesthesia with madetomidine-midazolam and butorphanol in dogs. J. Vet. Med. 2000, 47, 411-420.
  • 9. Klide A. M., Calderwood H. W., Soma L. R.: Cardiopulmonary effects of xylazine in dogs. Am. J. Vet. Res. 1975, 36, 931-935.
  • 10. Kojima K., Nishimura R., Mutoh T., Takao K., Matsunaga S., Mochizuki M., Sasaki N.: Comparison of cardiopulmonary effects of medetomidine-midazolam, acepromazine-butorphanol and midazolam-butorphanol in dogs. J. Vet. Med. 1999, 46, 353-359.
  • 11. Kojima K., Nishimura R., Mutoh T., Hong S. H., Mochizuki M., Sasaki N.: Effects of medetomidine-midazolam, acepromazine-butorphanol, and midazolam-butorphanol on induction dose of thiopental and propofol and on cardiopulmonary changes in dogs. Am. J. Vet. Res. 2002, 63, 1671-1679.
  • 12. Komar E., Balicki I., Lipp J., Żmuda P.: Badania porównawcze preparatów uspokajających Sedazin i Xylazine, Rompun i Rometar u zwierząt. Annales UMCS, sectio DD 1994, 49, 75-81.
  • 13. Komar E., Balicki I.: Wpływ atropiny, propofolu i atipamezolu na parametry hemodynamiczne psów. Annales UMCS sectio DD, 2000, 55, 135-140.
  • 14. Kostowski W., Kubikowski P.: Farmakologia. PZWL, Warszawa 1996.
  • 15. McClune S., McKay A. C., Wright P. M., Patterson C. C., Clarke R. S.: Synergistic interaction between midazolam and propofol. Br. J. Anaesth. 1992, 69, 240-245.
  • 16. Mutoh T., Nishimura R., Sasaki N.: Effects of medetomidine - midazolam, midazolam-butorphanol, or acepromazine-butorphanol as premedicants for mask induction of anesthesia with sevoflurane in dogs. Am. J. Vet. Res. 2002, 63, 1022-1028.
  • 17. Pypendop B., Serteyn D., Verstegen J.: Hemodynamic effects of medetomidine-midazolam-butorphanol and medetomidine-midazolam-buprenorphine combinations and reversibility by atipamezole in dogs. Am. J. Vet. Res. 1996, 57, 724-730.
  • 18. Raekllio M., Tulamo R. M., Valtamo T.: Medetomidine-midazolam sedation in sheep. Acta vet. scand. 1998, 39, 127-134.
  • 19. Ratajczak K.: Anestezjologia weterynaryjna. PWRiL, Warszawa 1985.
  • 20. Ronan K. P., Gallagher T. J., George B., Hamby B.: Comparison of propofol and midazolam for sedation in intensive care unit patients. Crit. Care. Med. 1995, 23, 286-293.
  • 21. Salonen M., Reid K., Maze M.: Synergistic interaction between a₂-adrenergic agonist and benzodiazepines in rats. Anesthesiol. 1992, 76, 1004-1011.
  • 22. Sano T., Nishimura R., Mochizuki M., Sasaki N.: Effects of midazolam-butorphanol, acepromazine-butorphanol and medetomidine on an induction dose of propofol and their compatibility in dogs. J. Vet. Med. Sci. 2003, 65, 1141-1143.
  • 23. Short C. E.: Principles and Practice of Veterinary Anesthesia. Williams and Wilkins, Boltimore 1987.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

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