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2007 | 63 | 02 |

Tytuł artykułu

Decreased serum adenosine deaminase activities in Van cats with feline retroviruses infections

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
This aim of the study was to determine the activity of ADA serum and isoenzyme in feline retroviral infections. The study involved 6 FeLV seropositive, 4 FIV seropositive and 10 healthy seronegative cats aged between 1-8 years. Haematological, serum enzyme acivity (AST; ALT; ALP; GGT) as well as ADA serum and isoenzyme activity were determined in all the cats. Haematological parameters were within the normal range except for the platelet count in FIV seropositive cats (p<0.05). Serum enzyme activity was unchanged except for the AST concentration in FeLV and FIV seropositive cats compared to the healthy subjects. ADA serum and ADA1 concentrations were lower in the seropositive group than in the seronegative group. However, the decrease in ADA serum and ADA1 concentrations in FIV seropositive cats (p<0.01) was more significant than that of FeLV seropositive cats (p<0.05). In conclusion, decreased ADA and ADA1 activity in feline retrovirus infections may be significant.

Wydawca

-

Rocznik

Tom

63

Numer

02

Opis fizyczny

p.184-186,ref.

Twórcy

autor
  • University of Yuzuncu Yil, 65080, Van, Turkey
autor
autor
autor

Bibliografia

  • 1. Altuğ N., Ağaoğlu Z. T.: Serum adenosine deaminase activity in dogs: It's importance in experimental liver intoxication. Isr. J. Vet. Med. 2000, 55, 129-134.
  • 2. Baganha M. F., Pêgo A., Lima M. A., Gaspar E. V., Cordeiro A. R.: Serum and pleural adenosine deaminase: correlation with lymphocytic populations. Chest 1990, 97, 605-610.
  • 3. Bremer H., Bauer I., Brock J.: Adenosine deaminase activity and immune dysfunction. Allerg. Immunol. 1981, 27, 3-13.
  • 4. Canbolat O., Ulusoyduran S., Özgen G., Ceyhan I., Gümüşlü F., Akbay A.: The comparison of adenosine deaminase activity values with polymerase chain reaction results in patient with tuberculosis. J. Clin. Lab. Anal. 1999, 13, 209-212.
  • 5. Casoli C., Lisa A., Magnani G., Fiaccador F., Bertezzoni U.: Prognostic value of adenosine deaminase compared to other markers for progression to acquired immunodeficiency syndrome among intravenous drug users. J. Med. Virol. 1995, 45, 203-210.
  • 6. Copelan E. A., Waddell K. S., Johnson S. C., Mathes L.: Purine metabolism in Feline Lymphomas. Vet. Pathol. 1990, 27, 117-121.
  • 7. Daddona P. E., Mitchell B. S, Meuwissen H. J, Davidson B. L., Wilson J. M., Koller C. A.: Adenosine deaminase deficiency with normal immune function. An acidic enzyme mutation. J. Clin. Invest. 1983, 72, 483-492.
  • 8. Gakis C., Calia G. M., Naitana A. G. V., Ortu A. R., Contu A.: Serum and pleural adenosine deaminase activity. Chest 1991, 99, 1555-1556.
  • 9. Giusti G., Galanti B.: Colorimetric Method, [in:] Bergmeyer H. U. (ed.): Methods of enzymatic analysis, Verlag Chemie, Weinheim 1984, p. 315-323.
  • 10. Hershfield M. S.: Apparent suicide inactivation of human lymphoblast S-adenosylhomocysteine hydrolase by 2-deoxyadenosine and adenine arabinoside. A basis for direct toxic effect of analogs of adenosine. J. Biol. Chem. 1979, 254, 22-25.
  • 11. Hofmann-Lehmann R., Holznagel E., Ossent P., Lutz H.: Parameters of Disease in Long-Term Experimental Feline Retrovirus (Feline Immunodeficiency Virus and Feline Leukemia Virus) Infections: Hematology, Clinical Chemistry and Lymphocyte Subsets. Clin. Diagn. Lab. Immun. 1997, 4, 33-42.
  • 12. Hoover E. A., Mullins J. I.: Feline leukemia virus infection and diseases. JAVMA 1991, 199, 1287-1297.
  • 13. Inigo M. A., Tejeda M. R. L., Tortosa M. T., Porto A. S., Ugarte I., Lomas E. G., Nestares A. M.: Serum adenosine deaminase in human immunodeficiency virus infection. Its relartionship with CD4+ lymphocytes and beta 2-microglobulin. Med. Clin. (Barc). 1992, 99, 766-768.
  • 14. Ishida T., Taniguchi A., Matsumura S., Washizu T., Tomoda I.: Long-term clinical observations on feline immunodeficiency virus infected asymptomatic carriers. Vet. Immunol. Immunopathol. 1992, 35, 15-22.
  • 15. Jain N. C.: Schalm's Veterinary Hematology. Lea Febiger, Philadelphia 1986, 602-622.
  • 16. Klockars M., Kleemola M., Leinonen M., Koskela M.: Serum adenosine deaminase in viral and bacterial pneumonia. Chest. 1991, 99, 623-626.
  • 17. Kurata N.: Adenosine deaminase. Nippon Rinsho. 1995, 53, 1178-1183.
  • 18. Magnuson N. S., Perryman L. E., Mason P. H., Marta K. M.: Distribution of enzymes of purine metabolism in lymphocytes of horse, Equus Caballus. Comp. Biochem. Physiol. (B). 1985, 81, 459-465.
  • 19. Morgan G., Levinsky R. J., Hugh-Jones K., Fairbanks L. D., Morris G. S.: Heterogeneity of biochemical, clinical and immunological parameters in severe combined immunodeficiency due to adenosine deaminase deficiency. Clin. Exp. Immunol. 1987, 70, 491-499.
  • 20. Pedersen N. C., Barlough J. E.: Clinical overwiew of feline immunodeficiency virus. JAVMA 1991, 199, 1298-1304.
  • 21. Renouf J. A., Wood A., Frazer I. H., Thong Y. H., Chalmers A. H.: Depressed activities of purine enzymes in lymphocytes of patients infected with human immunodeficiency virus. Clin. Chem. 1989, 35, 1478-1481.
  • 22. Reuter H., Burgess L. J., Carstens M. E., Doubell A. F.: Adenosine deaminase activity - more than a diagnostic tool in tuberculous pericarditis. Cardiovasc. J. South Afr. 2005, 16, 143-147.
  • 23. Rodman L. E., Farnell D. R., Coyne J. M., Allan P. W., Hill D. L., Duncan D. L., Tomaszewski J. E., Smith A. C.: Toxicity of cordycepin in combination with the adenosine deaminase inhibitor 2'-deoxycoformycin in beagle dogs. Toxicol. Appl. Pharmacol. 1997, 147, 39-45.
  • 24. Rojko J. I., Kociba G. J.: Pathogenesis of infection of feline leukemia virus. JAVMA 1991, 199, 1305-1310.
  • 25. Shelton G. H., Linenberger M. L., Abkowitz J. L.: Hematologic abnormalities in cats seropositive for feline immunodeficiency virus. JAVMA 1991, 199, 1353-1357.
  • 26. Shelton G. H., Linenberger M. L., Grant C. K., Abkowitz J. L.: Hematologic manifestations of feline immunodeficiency virus infection. Blood 1990, 76, 1104-1109.
  • 27. Shelton G. H., Linenberger M. L., Persik M. T., Abkowitz J. L.: Prospective hematologic and clinicopathological study of asymptomatic cats with naturally acquired feline immunodeficiency virus-infection. Vet. Intern. Med. 1995, 9, 133-140.
  • 28. Shimokata K.: Commemorative lecture on receiving Imamura Memorial Prize. Analysis of cellular immunity against tuberculosis in man with special reference to tuberculous pleurisy and cytokines. Kekkaku. 1996, 71, 591-596.
  • 29. SPSS: Statistical Package for Social Sciences for Windows. SPSS Inc. Co., USA 2002.
  • 30. Taher Z., Habibullah C. M., Saleem Y.: Decreased adenosine deaminase activity in peripheral lymphocytes of patients suffering from amebic liver abscess. Arch. Med. Res. 1993, 24, 203-204.
  • 31. Tanabe T.: Adenosine deaminase activities in the sera and tissues of animals and their clinical significance. Jpn. J. Vet. Res. 1993, 41, 1.
  • 32. Tarhan G., Gümüþlü F., Yilmaz N., Saka D., Ceyhan İ., Cesur S.: Serum Adenosine Deaminase Enzyme and Plasma Platelet Factor 4 Activities in Active Pulmonary Tuberculosis, HIV-seropositive Subjects and Cancer Patients. J. Infect. (article in press).
  • 33. Tompkins M. B., Nelson P. D., English R. V., Novotney C.: Early events in the immunopathogenesis of feline retrovirus infections. JAVMA 1991, 199, 1311-1315.
  • 34. Tsoboi I., Sagawa K., Shichijo S., Yokoyama M. M., Ou D. W., Wiederhold M. D.: Adenosine Deaminase Isoenzyme Levels in Patients with Human T-Cell Lymphotropic Virus Type 1 and Human Immunodeficiency Virus Type 1 Infections. Clin. Diagn. Lab. Immun. 1995, 2, 626-630.
  • 35. Ungerer J. P. J., Oosthuizen H. M., Retief J. H., Bissbort S. H.: Significance of adenosine deaminase activity and its isoenzymes in tuberculous effusions. Chest 1994, 106, 33-37.
  • 36. Yasuda K., Sei Y., Yokoyama M. M., Tanaka K., Hara A.: Healthy HTLV-1 carriers in Japan: haematological and immunological characteristics. Br. J. Haematol. 1986, 64, 195-203.
  • 37. Yüksek N., Kaya A., Altuğ N., Özkan C., Ağaoğlu Z. T.: Prevalance of Feline Retrovirus Infections in Van Cats. Bull. Vet. Inst. Pulawy 2005, 49, 375-377.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

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