EN
Propofol is an intravenous anaesthetic in which the active substance is 2.6-diizopropylphenol. It may be used for intravenous infusions in single or fractionated doses. Propofol was applied to 25 sheep of both sexes. Anaesthesia was induced with a saturation dose of 6.75 mg/kg bw/min. Afterwards, the substance was applied in sustaining doses. The total dose of Propofol was 0.44 mg/kg bw/min. The animals were under anaesthesia for 45 min. Haematological and biochemical parameters in sheep (10 examined animals) varied within the normal range. Myorelaxation and analgesia proved to be good. When Propofol administration ceased, the animals woke up quite quickly and attained the same state as before anaesthesia. In the course of anaesthesia Propofol should be administered continuously.