Arsenical - induced transcriptional activation of the yeast Saccharomyces cerevisiae ACR2 and ACR3 genes requires the presence of the ACR1 gene product

• Autorzy: Bobrowicz P. , Ulaszewski S.
• Języki publikacji: EN

Abstrakty

EN

The yeast ACR1 gene encodes a putative transcriptional regulatory bZIP protein involved in the arsenical resistance. We demonstrate that the ACR2 and ACR3 genes are positively regulated by Acr1p. Changes in the ACR1 gene dosage influence the ACR2-lacZ and ACR3-lacZ fusion genes response to the arsenite induction. Arsenic and antimony compounds, but not bismuth and cadmium salts, strongly induced the expression of the ACR3 gene encoding the arsenite transporter related to the prokaryotic ArsB proteins.

Słowa kluczowe

EN

yeast; antimony potassium tartrate; sodium arsenate; gene expression; plasmid; bismuth nitrate; sodium arsenite; cadmium sulphate; beta-galactosidase activity; arsenical resistance; Saccharomyces cerevisiae

• Wydawca: -
• Czasopismo: Cellular and Molecular Biology Letters
• Rocznik: 1998
• Tom: 03
• Numer: 1
• Opis fizyczny: p.13-20,fig.

Twórcy

autor

Bobrowicz P.

• Wroclaw University, Przybyszewskiego 63, 51-148 Wroclaw, Poland

autor

Ulaszewski S.

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