PL EN


Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników

Czasopismo

2004 | 63 | 1 |

Tytuł artykułu

A preliminary evaluation of thyroid and respiratory tract neuroendocrine cells in the rat after experimental hypercalcaemia

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
The goal of this study was to investigate the influence of experimentally induced hypercalcaemia (after 100000 UI Vigantol and CaCl₂) on neuroendocrine cells (NECs) in the thyroid and airways in the rat. After 24 h, 7 days and 14 days the thyroid and lungs were collected. Paraffin sections were immunocytochemically stained with specific antibodies against CGRP, calcitonin (CT) and synaptophysin (SY) in the airway NECs and thyroid C cells. The largest hypercalcaemia were observed in experimental rats after 7 days. More significant changes in the number and size of neuroendocrine cells were observed in the thyroid gland as well as in the airways. In the airways only a slight increase in the number of neuroepithelial bodies (NEBs) was observed, some of which gave evidence of hypertrophy symptoms.

Słowa kluczowe

Wydawca

-

Czasopismo

Rocznik

Tom

63

Numer

1

Opis fizyczny

p.111-113,fig.,ref.

Twórcy

autor
  • Medical University, Kilinskiego 1, 15-089 Bialystok, Poland
autor

Bibliografia

  • 1. Cutz E, Jackson A (1999) Neuroepithelial bodies as airway oxygen sensors. Respir Physiol, 115: 201–214.
  • 2. Kasacka I, Azzadin A, Sawicki B (2001) Immunoreactivity of neuroendocrine cells in the respiratory tract in rats with experimental uremia after thyroparathyroidectomy. Folia Histochem Cytobiol, 39: 64–65.
  • 3. Reynolds SD, Giangreco A, Power JHT, Stripp BR (2000) Neuroepithelial bodies of pulmonary airways serve as a reservoir of progenitor cells capable of epithelial regeneration. Am J Pathol, 156: 269–278.
  • 4. Sawicki B., Kasacka I., Azzadin A., Dadan J., Malla C., Nowosielski C., Buczko W. Niklińska W (2001) Preliminary evaluation of endocrine cells in the rat respiratory tract after thyroid and parathyroid gland removal. Folia Histochem Cytobiol, 39: 193–194.
  • 5. Sekulic M, Lovren M, Milosevic V, Micic M, Balint Peric L (1998) Thyroid C cells of middle-aged rats treated with estradiol or calcium. Histochem Cell Biol, 109: 257–262.
  • 6. Sexton P, Findlay D, Martin T (1999) Calcitonin. Curr Med Chem, 6: 1067-1093.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

bwmeta1.element.agro-article-cf5d77b1-ec74-4d91-8c95-ee5f6bdb00b2
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.