Wplyw stosowania u zwierzat antybiotykow na lekoopornosc bakterii chorobotworczych dla czlowieka

• Autorzy: Truszczynski M , Pejsak Z.

Warianty tytułu

EN

Influence of antibiotics used in animals on antibiotic resistance to bacteria pathogenic for man

• Języki publikacji: PL

Abstrakty

EN

The mechanisms of antibiotic resistance of bacteria have been presented, including spontaneous mutation, gene transfer and selection. Examples of the contribution of antimicrobial growth promoters to the domination of antibiotic resistant bacteria, pathogenic for humans and animals in bacterial populations, have been cited. The results obtained were the basis for the introduction of a ban prohibiting the use of antimicrobial growth promoters in animal feeds in Sweden, Denmark and some other Western European countries. The bans have resulted in a significant decrease of the number of antibiotic resistant bacteria in the animal reservoir, being of importance for public health. Taking this into account, since January the 1st 2006 the European Union has introduced a ban on the use of antimicrobial growth promoters for food animals for all member countries. Besides the positive effects of the earlier bans, negative consequences have also been observed, such as an increase of bacterial diseases and mortality in young poultry and weaners, higher expenses for veterinary interventions, a decrease of daily body gain and feed effectivity. The negative effects were noticed particularly in farms with insufficient animal welfare and management. Opinions have been cited indicating that the risk to human health connected with the use of antibiotics in food animals, including growth promoters, was not as high as expressed by the public health representatives. Final conclusions on this topic, however, require further research.

Słowa kluczowe

PL

zagrozenia zdrowia; lekoopornosc; choroby bakteryjne; opornosc na antybiotyki; antybiotyki; bakterie chorobotworcze; leczenie; choroby zwierzat; czlowiek

• Wydawca: -
• Czasopismo: Medycyna Weterynaryjna
• Rocznik: 2006
• Tom: 62
• Numer: 12
• Opis fizyczny: s.1339-1343,rys.,tab.,bibliogr.

Twórcy

autor

Truszczynski M

• Panstwowy Instytut Weterynaryjny - Panstwowy Instytut Badawczy, Al.Partyzantow 57, 24-100 Pulawy

autor

Pejsak Z.

Bibliografia

• 1.Aarestrup F. M., Bager F., Jensen N. E., Madsen M., Meyling A., Wegener H. C.: Resistance to antimicrobial agents and for animal therapy in pathogenic, zoonotic and indicator bacteria isolated from different food animals in Denmark: A base-line study for the Danish Integrated Antimicrobial Resistance Monitoring Programme (DANMAP). APMIS. 1998, 106, 745- -770.
• 2.Aarestrup F. M., Seyfarth A. M., Emborg H. D., Pedersen K., Hendriksen R. S., Bager F.: Effect of abolishment of the use of antimicrobial agents for growth promotion on occurrence of antimicrobial resistance in fecal enterococci from food animals in Denmark. Antimicrob. Agents Chemother. 2001, 45, 2054- -2059.
• 3.Aarestrup F. M.: Effect of termination of AGP use on antimicrobial resistance in food animals. DIAS report. Animal Husbandry. 2004, 57, 9-16.
• 4.Acar J., Röstel B.: Antimicrobial resistance: overview. Rev. sci. tech. Off. int. Epiz. 2001, 20, 797-810.
• 5.Anthony F., Acar J., Franklin A., Gubata R., Nicholss T., Tamura Y., Thompson S., Threlfall E. J., Vose D., Vuuren van M., White D. G.: Antimicrobial resistance: responsible and prudent use of antimicrobial agents in veterinary medicine. Rev. sci. tech. Off. int. Epiz. 2001, 20, 829-839.
• 6.Casewell M., Friis C., Marco E.: The European ban on growth promoting antibiotics and emerging consequences for human and animal health. J. Antimicrob. Chemotherapy. 52, 159-161.
• 7.Cullesen J.: Effects of termination of AGP-use in pig welfare and production. DIAS report. Anim. Husbandry 2004, 57, 57-60.
• 8.Deu S. B.: Ograniczanie strat wywołanych przez zakażenie Escherichia coli i Clostridium perfringens u świñ w sytuacji zakazu stosowania antybiotykowych stymulatorów wzrostu. Życie Wet. 2005, 80, 769-771.
• 9.Dupont J., Fraise A., Wise R.: Use of antimicrobial agents in animal feeds: implications for human health. Rev. Inf. Dis. 1987, 9, 447-460.
• 10.Evans M. C., Wegener H. C.: Antimicrobial growth promoters and Salmonella spp. Campylobacter spp. in poultry and swine, Denmark. Emerging Inf. Dis. 2003, 9, 489-492.
• 11.Franklin A., Acar J., Anthony F., Gupta R., Nicholls T., Tamura J., Thompson S., Threlfall E. J., Vose D., van Vuuren M., White D. G., Wegener H. C., Costarrica M. L.: Antimicrobial resistance harmonization and national antimicrobial resistance monitoring and surveillance programmes in animals and animal-derived food. Rev. sci. tech. Off. int. Epiz. 2001, 20 859-870.
• 12.Gaskins H. R., Collier C. C., Anderson D. B.: Antibiotics as growth promoters: mode of action. Anim. Biotechnol. 2002, 13, 29-42.
• 13.Jensen L. B., Ahrens P., Dons L.: Transient intestinal carriage after ingestion of antibiotic resistant Enterococcus faecium from chicken and pork. New England J. Med. 2001, 345, 1161-1166.
• 14.Klare J., Badstubar D., Konstabel C.: Decreased incidence of VanA-type vancomycin-resistant enterococci isolated from poultry meat and from fecal samples of humans in the community after discontinuation of avoparcin usage in animal husbandry. Microb. Drug Res. 1999, 5, 45-52.
• 15.Mathews K. H.: Antimicrobial drug use and veterinary costs in U.S. livestock production. USDA Agric. Inform. Bull. 2001, 766, 1-8.
• 16.McEwen S. A., Fedorka-Cray P. J.: Antimicrobial use and resistance in animals. Clin. Inf. Dis. 2002, 34, 93-106.
• 17.McEwen S. A.: Improve antibiotic use in animals. Antibiotic Resistance: Syntheses of Recommendations by Expert Policy Groups, WHO/CDS/CSR/ DRS/2001. 10, 65-79.
• 18.Pejsak Z., Truszczyñski M.: Racjonalne stosowanie chemioterapeutyków w terapii i profilaktyce. Życie Wet. 2005, 80, 642-645.
• 19.Phillips J., Casewell M., Cox T., de Groot B., Fries Ch., Jones R., Nightingale Ch., Preston R., Waddell J.: Does the use of antibiotics in food animals pose a risk to human health? A critical review of published data. J. Antimicrob. Chemotherapy 2004, 53, 28-52.
• 20.Piddock L. J. V.: Fluoroquinolone resistance in Salmonella serovars isolated from humans and food animals. FEMS Microbiol. Rev. 2002, 26, 3-16.
• 21.Truszczyñski M., Borkowska-Opacka B.: Występowanie zjawiska zakaźnej lekooporności u szczepów Salmonella izolowanych od zwierząt. Med. Dośw. Mikrobiol. 1970, 22, 111-117.
• 22.Van den Bogaard A. E., Bruinsma N., Stalberingh E. E.: The effect of banning avoparcin on VRE carriage in the Netherlands. J. Antimicrob. Chemotherapy 2000, 46, 146-147.
• 23.Vose D., Acar J., Anthony F., Franklin A., Gupta R., Nicholls T., Tamura Y., Thompson S., Threlfall E. J., van Vuuren M., White D. G., Wegener H. C., Costarrica M. L.: Antimicrobial resistance: risk analysis methodology for the potential impact on public health and antimicrobial resistant bacteria of animal origin. Rev. sci. tech. Off. int. Epiz. 2001, 20, 811-827.
• 24.Wegener H. C., Aarestrup F. M., Jensen L. B., Hammerum A. M., Flemming B.: Use of antimicrobial growth promoters in food animals and Enterococcus faecium resistance to therapeutic antimicrobial drugs in Europe. Emerg. Inf. Dis. 1999, 5.