PL
Badano oddziaływanie węglanu magnezu (w dawce 20 mg Mg/kg m.c./ 24 h) w czasie jego podawania oraz po zaprzestaniu suplementacji na bilans magnezu i żelaza oraz ich zawartość w narządach, płynach ustrojowych i sierści szczurów. Stwierdzono znaczne obniżenie współczynnika retencji pozornej żelaza oraz zmiany w jego zawartości w tkankach. Nie wykazano zmian w retencji magnezu.
EN
The effect of magnesium supplementation with 20 mg Mg/kg b.w./24 h on the metabolism of magnesium and iron in rats was investigated. Magnesium carbonate suspended in 2% gum arabie was administered to male Wistar rats by stomach intubation during 4 weeks. The controls received an equal volume of 2% gum arabie. During the next 4 weeks, the experiment was continued without magnesium supplementation. The animals of both groups were sacrificed after 2, 4, 6 and 8 weeks of the experiment. The concentration of magnesium and iron was determined by atomic absorption spectrometry in tissues, blood, urine feces and hair. Magnesium and iron retention was calculated. It was found that magnesium retention was higher only after 2 and 6 weeks of the experiment. Magnesium concentration in spleen, brain and liver was not changed, however, it increased in the intestine and hair. A decreased magnesium concentration was found in the heart. Iron retention decreased during the whole experiment. The concentration of iron increased in brain, kidneys and blood serum, and decreased in bone. The results show that oral intake of magnesium at 20 mg/kg b.w./24 h during 4 weeks is able to change iron metabolism.