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2008 | 64 | 03 |

Tytuł artykułu

D-dimer jako wskaznik wykrzepiania wewnatrznaczyniowego u koni i psow

Warianty tytułu

EN
D-dimer as an indicator of intravascular clotting in horses and dogs

Języki publikacji

PL

Abstrakty

EN
Clotting disturbances are well documented in veterinary medicine and associated with bleeding caused by damage of coagulate cascade. Homeostasis is defined as the equilibrium between coagulation and fibrinolysis. It is a complicated physiological process protecting the organism against blood loss. As a result of new immunological technology with high specific and sensitive markers it is possible to detect products of fibrynolysis activation, such as D-dimers. Veterinary literature has published very little about the efficacy of various D-dimer test in dogs and horses in diagnosing and evaluating the increase in fibrynogen degradation products. It has been proven that completing standard parameters (pulse, respiration, PCV and anion gap) estimated in horses with colic by using the D-dimer test as well as assessing the activity of phospolipase A₂, the animal’s life expectancy prognosis is radically improved. Because homeostatic cascade activation occurs due to many clinical causes e.g.: injury, chirurgical operation, neoplasm, heart diseases, pregnancy and in the postpartum period, it seems theoretically reasonable to apply the D-dimer test in order to access early diagnosis of life-dangerous abnormalities such as circulative thrombi in blood vessels.

Wydawca

-

Rocznik

Tom

64

Numer

03

Opis fizyczny

s.272-275,bibliogr.

Twórcy

autor
  • Uniwersytet Przyrodniczy we Wroclawiu, pl.Grunwaldzki 47, 50-366 Wroclaw
autor
autor
autor

Bibliografia

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  • 2.Carr J. M., McKinney S. B., McDonagh J.: Diagnosis of disseminated intravascular coagulation. Am. J. Clin. Path. 1989, 91, 280-287.
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  • 4.Collatos C., Barton M. H., Prasse K. W., Moore J. N.: Intravascular and peritoneal coagulation and fibrinolysis in horses with acute gastrointestinal tract diseases. JAVMA 1995, 207, 465-470.
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  • 6.Darien B. J., Potempa J., Moore J. N., Travis J.: Antithrombin III activity in horses with colic: an analysis of 46 cases. Equine Vet. J. 1991, 23, 211-214.
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  • 8.Feldman F. B.: Clinical Hemostasis. WSAVA Congress 2002, 291-292.
  • 9.Freyburger G., Trillaud H., Labrouche S.: D-dimer strategy in thrombosis exclusion - a gold standart study in 100 patients suspected of deep venous thrombosis or pulmonary embolism:8 DD methods compared. Thromb. Haemost. 1998, 79, 32-37.
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  • 18.Monreal L.: Editorial: D-dimer as a New Test for the Diagnostic of DIC and Thromboembolic Disease. J. Vet. Inter. Med. 2003, 17, 757-759.
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  • 28.Solnica B.: Dimer D. Medycyna Prakt. 2004, 07, 149-151.
  • 29.Stokol T., Brookes M. B., Erb H. N., Mauldin G. E.: D-dimer concentrations in healthy dogs and dogs with disseminated intravascular coagulation. Am. J. Vet. Res. 2000, 61, 393-398.
  • 30.Stokol T., Erb H. N., De Wilde L., Tornquist S. J., Brooks M.: Evaluation of latex agglutination kits for detection of fibrin(ogen) degradation products and D-dimer in healthy horses and horses with severe colic. Vet. Clin. Pathol. 2005, 34, 375-382.
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Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

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