The influence of tin compounds on the dynamic properties of liposome membranes: a study the ESR method

• Autorzy: Man D , Podolak M. , Engel G.
• Języki publikacji: EN

Abstrakty

EN

The influence of organic and inorganic compounds of tin on the dynamic properties of liposome membranes obtained in the process of dipalmitoylphosphatidylcholine (DPPC) sonication in distilled water was investigated. This was carried out by means of the spin ESR probe method. The probes were selected in such a way as to penetrate different areas of the membrane (a TEMPO probe, 5-DOXYL stearic acid, 16-DOXYL stearic acid). Four compounds of tin were chosen: three organic ones, (CH3)4Sn, (C2H5)4Sn and (C3H7)3SnCl, and one inorganic one, SnCl2. The investigated compounds were added to a liposome dispersion, which was prepared prior to that. The concentration of the admixture was changed within the values from 0 to 10%-mole in proportion to DPPC. The studies indicated that the chlorides of tin display the highest activity in their interaction with liposome membranes. Since these compounds have ionic form in a water solution, the obtained result can mean that this form of admixture has a considerable influence on its activity. Furthermore, it was found that there is a slightly stronger influence of tin compounds with a longer hydrocarbon chain on changes in the probes’ spectroscopic parameters.

Słowa kluczowe

EN

ESR method; dynamic property; tin compound; dipalmitoylphosphatidylcholine; liposome membrane

• Wydawca: -
• Czasopismo: Cellular and Molecular Biology Letters
• Rocznik: 2006
• Tom: 11
• Numer: 1
• Opis fizyczny: p.56-61,fig.,ref.

Twórcy

autor

Man D

• Opole University, Oleska 48, 45-052 Opole, Poland

autor

Podolak M.

autor

Engel G.

Bibliografia

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