The activity and immunoexpression of cathepsin D in rat male reproductive organs

• Autorzy: Burdan F , Szumilo J. , Dudka J. , Dabrowski A. , Maciejewski R. , Wojtowicz Z.
• Języki publikacji: EN

Abstrakty

EN

Cathepsin D is a cysteine endopeptidase that belongs to the lysosomal enzyme family. The aim of the study was to evaluate the enzyme immunoexpression and activity in selected male genital organs in mature Wistar rats. The activity of cathepsin D was measured spectrophotometrically in homogenates of the testis, epididymis, seminal vesicle and prostate. Immunohistochemical staining was also performed in the ductus deferens. Enzyme activity was found in the following sequence: testis>epididymis>dorsal prostatic lobe>seminal vesicle>lateral prostatic lobe>ventral prostatic lobe. Although there were differences in enzyme activity between various organs of the male reproductive system, cathepsin D immunoreactivity was seen exclusively in the Sertoli and Leydig cells in the testis.

Słowa kluczowe

EN

enzyme activity; lysosomal enzyme; epididymis; seminal vesicle; prostate; immunoexpression; cathepsin D; rat; male; reproductive organ

• Wydawca: -
• Czasopismo: Folia Morphologica
• Rocznik: 2006
• Tom: 65
• Numer: 2
• Opis fizyczny: p.111-115,fig.,ref.

Twórcy

autor

Burdan F

• Medical University of Lublin, Lublin, Poland

autor

Szumilo J.

autor

Dudka J.

autor

Dabrowski A.

autor

Maciejewski R.

autor

Wojtowicz Z.

Bibliografia

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