PL EN


Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników
2008 | 64 | 05 |

Tytuł artykułu

Regulacja sekrecji melatoniny w szyszynce ptakow

Autorzy

Warianty tytułu

EN
Regulation of melatonin secretion in the avian pineal gland

Języki publikacji

PL

Abstrakty

EN
The avian pineal gland releases melatonin in a cyclic manner, with the highest level at night and the lowest level during the daytime. Mechanisms regulating melatonin secretion in birds are very complex, probably due to the phylogenetic position of the avian pineal gland as an intermediate form between the pineals of lower vertebrates and mammals. Avian pinealocytes possess an endogenous oscillator, formed by a self-regulated system of cock genes, that controls the transcription of several enzymes, among them arylalkylamine N-acetyltransferase (AA-NAT), the enzyme limiting melatonin synthesis. These cells are also directly photosensitive due to the presence of photopigments, pinopsin and melanopsin, as well as corresponding signal transduction systems. Light acting via pinopsin induces a cascade of events that leads to the decrease in cGMP and cAMP levels, AA-NAT activity and melatonin secretion. Melanopsin is probably involved in an entrainment of the circadian oscillator to the environmental light conditions. The function of the avian pineal gland is also regulated by light acting indirectly via the retina as well as by the extrapineal oscillator located in the suprachiasmatic nucleus. Both structures influence the pinealocyte activity via a common multisynaptic pathway, which ends in the gland as the sympathetic nerve fibers. Norepinephrine released from these fibers stimulates α₂-adrenoreceptors in pinealocyte plasmalemma and inhibits adenylate cyclase activity and melatonin secretion. The significance of direct and indirect routes of light perception as well as intra- and extra-pineal oscillators in the regulation of melatonin secretion may differ between species, but this problem is poorly recognized.

Wydawca

-

Rocznik

Tom

64

Numer

05

Opis fizyczny

s.639-645,rys.,fot.,bibliogr.

Twórcy

autor
  • Uniwersytet Warminsko-Mazurski w Olsztynie, ul.Oczapowskiego 13, 10-713 Olsztyn
autor

Bibliografia

  • 1. Barrett R. K., Underwood H.: The superior cervical ganglia are not necessary for entrainment or persistence of the pineal melatonin rhythm in Japanese quail. Brain Res. 1992, 569, 249-254.
  • 2. Bernard M., Guerlotte J., Cogne M., Greve P., Collin J. P., Voisin P.: Transcriptional regulation of hydroxyindole-O-metyltransferase in the chicken pineal gland: day/night changes and long-term effects of light and darkness. Biochem. J. 1993, 290, 661-664.
  • 3. Bernard M., Iuvone P. M., Cassone V. M., Roseboom P. H., Coon S. L., Klein D. C.: Avian melatonin synthesis: photic and circadian regulation of serotonin N-acetyltransferase mRNA in the chicken pineal gland and retina. J. Neurochem. 1997, 68, 213-224.
  • 4. Cassone V. M., Forsyth A. M., Woodlee G. L.: Hypothalamic regulation of circadian noradrenergic input to the chick pineal gland. J. Comp. Physiol., A Sens. Neural Bahav. Physiol. 1990, 167, 187-192.
  • 5. Chaurasia S. S., Provencio I., Jiang G., Hayes W. P., Natesan A., Zatz M., Rollag M. D., Iuvone P. M.: Differential circadian regulation of melanopsin mRNA expression in the avian retina and pineal gland. Invest. Ophthalmol. Vis. Sci. 2004, 45, 46-48.
  • 6. Csernus V., Faluhelyi N., Nagy A. D.: Features of the circadian clock in the avian pineal gland. Ann. N. Y. Acad. Sci. 2005, 1040, 281-287.
  • 7. Csernus V., Józsa R., Reglõdi D., Hollósy T., Somogyvári-Vigh A., Arimura A.: The effect of PACAP on rhythmic melatonin release of avian pineals. Gen. Comp. Endocrinol. 2003, 135, 62-69.
  • 8. D'-Souza T., Dryer S. E.: A cationic channel regulated by a vertebrate intrinsic circadian oscillator. Nature 1996, 382, 165-167.
  • 9. Deguchi T.: Rhodopsin-like photosensivity of isolated chicken pineal gland. Nature 1981, 290, 706-707.
  • 10. Green C. B., Besharse J. C., Zatz M.: Tryptophan hydroxylase mRNA levels are regulated by the circadian clock, temperature, and cAMP in chick pineal cells. Brain Res. 1996, 738, 1-7.
  • 11. Greve P., Voisin P., Grechez-Cassiau A., Bernard M., Collin J. P., Guerlotte J.: Circadian regulation of hydroxyindole-O-methyltransferase mRNA in the chicken pineal gland in vivo and in vitro. Biochem. J. 1996, 319, 761-766.
  • 12. Harrison N. L., Zatz M.: Voltage-dependent calcium channels regulate melatonin output from cultured chick pineal cells. J. Neurosci. 1989, 9, 2462-2467.
  • 13. Holthues H., Engel L., Spessert R., Vollrath L.: Circadian gene expression patterns of melanopsin and pinopsin in the chick pineal gland. Biochem. Biophys. Res. Commun. 2005, 326, 160-165.
  • 14. Holthues H., Vollrath L.: The phototransduction cascade in the isolated chick pineal gland revisited. Brain Res. 2004, 999, 175-180.
  • 15. Kawamura S., Blow N. S., Yokoyama S.: Genetic analyses of visual pigments of the pigeon (Columbia livia). Genetics 1999, 153, 1836-1850.
  • 16. Lewczuk B.: Siatkówka, jądro skrzyżowania oraz szyszynka jako elementy zegara biologicznego ssaków. Medycyna Wet. 2007, 63, 506-511.
  • 17. Matsushita A., Yoshikawa T., Okano T., Kasahara T., Fukada Y.: Colocalization of pinopsin with two types of G-protein alpha-subunits in the chicken pineal gland. Cell Tissue Res. 2000, 299, 245-251.
  • 18. Max M., McKinnon P. J., Seidenman K. J., Barret R. K., Applebury M. L., Takahashi J. S., Margolskee R. F.: Pineal opsin: a nonvisual opsin expressed in chick pineal. Sci. 1995, 267, 1502-1506.
  • 19. Murakami N., Nakamura H., Nishi R., Marumoto N., Nasu T.: Comparison of circadian oscillation of melatonin release in pineal cells of house sparrow, pigeons and Japanese quail, using cell perfusion system. Brain Res. 1994, 651, 209-214.
  • 20. Nakahara K., Murakami N., Nasu T., Kuroda H., Murakami T.: Involvement of protein kinase A in the subjective nocturnal rise of melatonin release by chick pineal cells in constant darkness. J. Pineal Res. 1997, 23, 221-229.
  • 21. Natesan A., Geetha L., Zatz M.: Rhythm and soul in the avian pineal. Cell Tissue Res. 2002, 309, 35-45.
  • 22. Nikaido S. S., Takahashi J. S.: Day/night differences in the stimulation of adenylate cyclase activity by calcium/calmodulin in chick pineal cell cultures: evidence for circadian regulation of cyclic AMP. J. Biol. Rhythms 1998, 13, 479-493.
  • 23. Okano T., Fukada Y.: Chicktacking pineal clock. J. Biochem. 2003, 134, 791-797.
  • 24. Okano T., Takanaka Y., Nakamura A., Hirunagi K., Adachi A., Ebihara S., Fukada Y.: Immunocytochemical identification of pinopsin in the pineal glands of chicken and pigeon. Brain Res. Mol. Brain Res. 1997, 50, 190-196.
  • 25. Okano T., Yoshizawa T., Fukada Y.: Pinopsin is a chicken pineal photoreceptive molecule. Nature 1994, 372, 94-97.
  • 26. Pratt B. L., Takahashi J. S.: Vasoactive intestinal polypeptide and alpha2-adrenoreceptor agonists regulate adenosine 3',5'-monophosphate accumulation and melatonin release in chick pineal cell cultures. Endocrinol. 1989, 125, 2375-2384.
  • 27. Prusik M.: Mechanizmy regulujące sekrecję melatoniny w szyszynce indyka. Praca doktorska, UWM w Olsztynie 2005.
  • 28. Prusik M., Lewczuk B., Nowicki M., Przybylska-Gornowicz B.: Histology and ultrastructure of the pineal gland in the domestic goose. Histol. Histopathol. 2006, 21, 1075-1090.
  • 29. Reiter R. J.: Pineal melatonin: cell biology of its synthesis and of its physiological interactions. Endocrine Rev. 1991, 12, 151-180.
  • 30. Robertson L. M., Takahashi J. S.: Circadian clock in cell culture: II. In vitro photic entrainment of melatonin oscillation from dissociated chick pineal cells. J. Neurosci. 1988, 8, 22-30.
  • 31. Takanaka Y., Okano T., Iigo M., Fukada Y.: Light-dependent expression of pinopsin gene in chicken pineal gland . J Neurochem. 1998, 70, 908-913.
  • 32. Voisin P., Martin C., Collin J. P.: Alpha2-adrenergic regulation of arylkylamine N-acetyltransferase in organ-cultured chick pineal gland: characterization with agonists and modulation of experimentally stimulated enzyme activity. J. Neurochem. 1987, 49, 1421-1426.
  • 33. Vollrath L.: The pineal gland, [w:] Handbuch der mikroskopischen Anatomie des Menschen, VI/7. Springer Verlag, Berlin, Heidelberg 1981.
  • 34. Yamao M., Araki M., Okano T., Fukada Y., Oishi T.: Differentiation of pinopsinimmunoreactive cells in the developing quail pineal organ: an in vivo and in vitro immunohistochemical study. Cell Tissue Res. 1999, 296, 667-671.
  • 35. Zatz M.: Relationship between light, calcium influx and cAMP in the acute regulation of melatonin production by cultured chick pineal cells. Brain Res. 1989, 477, 14-18.
  • 36. Zatz M.: Photoendocrine transduction in cultured chick pineal cells. IV: What do vitamin A depletion and retinaldehyde addition do to the effects of light on the melatonin rhythm? J. Neurochem. 1994, 62, 2001-2011.
  • 37. Zatz M., Heath J. R.: Calcium and photoentrainment in chick pineal cells revisited: effects of caffeine, thapsigargin, EGTA, and light on the melatonin rhythm. J. Neurochem. 1995, 65, 1332-1341.
  • 38. Zatz M., Mullen D. A.: Does calcium influx regulate melatonin production through the circadian pacemaker in chick pineal cells? Effects of nitrendipine, Bay K 8644, Co²⁺, Mn²⁺, and low external Ca²⁺. Brain Res. 1988, 463, 305-316.
  • 39. Zatz M., Mullen D. A.: Photoendocrine transduction in cultured chick pineal cells. II. Effects of forskolin, 8-bromocyclic AMP, and 8-bromocyclic GMP on the melatonin rhythm. Brain Res. 1988, 453, 51-62.
  • 40. Zatz M., Mullen D. A.: Two mechanisms of photoendocrine transduction in cultured chick pineal cells: pertussis toxin blocks the acute but not the phase-shifting effects of light on the melatonin rhythm. Brain Res. 1988, 453, 63-71.
  • 41. Zawilska J. B., Lorenc A., Berezińska M., Vivien-Roels B., Pévet P., Skene D. J.: Diurnal and circadian rhythms in melatonin synthesis in the turkey pineal gland and retina. Gen. Comp. End. 2006, 145, 162-168.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

bwmeta1.element.agro-article-6c1e9afd-6033-4bc3-8dfc-456f09a439a1
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.