Synthesis of a quaternary polyprenyl ammonium salt

• Autorzy: Sizova O. V. , Utkina N.S. , Kalinchuk N.A. , Danilov L.L. , Maltsev S.D.
• Języki publikacji: EN

Abstrakty

EN

Reaction of primary C55-allylic alcohol moraprenol (WT3C7-9-OH, a polyprenol from mulberry leaves) with triethylamine in the presence of phosphorus oxychloride leads to a quaternary ammonium chloride with a good yield (72%) and high cis-stereoselectivity of the terminal isoprene unit. Cationic polyprenyl derivatives may be useful for transfection and immunological studies

Słowa kluczowe

PL

polyprenol; quaternary ammonium salt; cationic lipid; synthesis; immunology

• Wydawca: -
• Czasopismo: Acta Biochimica Polonica
• Rocznik: 2007
• Tom: 54
• Numer: 4
• Opis fizyczny: p.869-872,fig.,ref.

Twórcy

autor

Sizova O. V.

• Russian Academy of Sciences, Leninsky prospect 47, Moscow 119991, Russian Federation

autor

Utkina N.S.

autor

Kalinchuk N.A.

autor

Danilov L.L.

autor

Maltsev S.D.

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