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2007 | 63 | 01 |

Tytuł artykułu

Lekowrazliwosc bakterii izolowanych od koni z zakazeniami gornych drog oddechowych

Autorzy

Warianty tytułu

EN
Drug sensitivity of bacteria isolated from horses with upper respiratory tract infections

Języki publikacji

PL

Abstrakty

EN
The aim of the study was to analyse the antibiotic sensitivity of bacteria isolated from nasal mucosa of foals and young horses with upper respiratory tract infections. Included in the study were one hundred forty nine bacterial strains belonging to ten species: Staphylococcus aureus (4), Staphylococcus intermedius (4), Streptococcus equi subsp. zooepidemicus (12), Bordetella bronchiseptica (15), Klebsiella pneumoniae pneumoniae (1), Moraxella sp. (4), Pasteurella pneumotropica (2), Staphylococcus lentus (16), Staphylococcus sciuri (48), Staphylococcus xylosus (43). Antibiotic sensitivity tests were performed by the use of the disc diffusion method on Mueller-Hinton agar, according to NCCLS recommendations. Twenty six chemotherapeutics were used to assess antibiotic sensitivity profiles of: amoxicillin (AMX), amoxicillin with clavulic acid (AMC), ampicillin (AM), carbenicillin (CB), cefotaxim (CFM), cefuroxim (CXM), cefalexin (CN), chloramphenicol (C), erythromycin (E), flumequine (AR), gentamicin (GM), kanamycin (K), linkomycin (L), minocycline (MI), neomycin (N), nitrofurantoin (FM), norfloxacine (NOR), oksacillin (OX), penicillin G (P), rifampicin (RI), spiramycine (SP), streptomycin (S), sulphonamides (G), sulphonamides and trimethoprim (SXT), tetracycline (TE), vankomycine (VA). Results obtained during the study indicated the highest effectiveness of amoxicillin with clavulic acid (AMC), cephalosporines, gentamicin (GM), minocycline (MI), rifampicin (RI) and sulphonamides combined with trimethoprim (SXT) against the bacterial strains examined. The percentage of strains susceptible for AMC was 70.4%, cefalexin - 58.6%, cefotaxim - 62.1%, cefuroxim - 65.1%, GM - 61.3%, MI - 58.7%, RI - 67% and SXT - 58.4%. The highest (100%) resistance against chemotherapeutics examined in the study was demonstrated by the Klebsiella pneumoniae pneumoniae strain, isolated from suppurative lung lesions from a 2-month-old foal, showing pronounced respiratory signs antemortem and pneumonia lesions upon death.

Wydawca

-

Rocznik

Tom

63

Numer

01

Opis fizyczny

s.75-79,tab.,bibliogr.

Twórcy

autor
  • Akademia Rolnicza, ul.Gleboka 30,20-612 Lublin
autor

Bibliografia

  • 1. Anon.: NCCLS Draft: Performance Standards for Antimicrobial Disc and Dilution Susceptibility Test for Bacteria Isolated from Animals; Approved Standard Second Edition, Wayne 2001, 19, 11.
  • 2. Bayly W. M., Reed S. M., Traub J. L.: Equine Bronchopneumonia due to Bordetella bronchiseptica. Eq. Pract. 1982, 4, 25-32.
  • 3. Boguta L., Grądzki Z., Borges E., Maurin F., Kodjo A., Winiarczyk S.: Bacterial flora in foals with upper respiratory tract infections in Poland. J. Vet. Med. B. 2002, 49, 294-297.
  • 4. Boguta L.: Wybrane aspekty etiologii i epidemiologii molekularnej zakażeń górnych dróg oddechowych koni. Praca doktorska, AR Lublin 2004.
  • 5. Burrell M. H., Wood J. L. N., Whitwell K. E., Chanter N., Mackintosh M. E., Mumford J. A.: Respiratory disease in thoroughbred horses in training: the relationships between disease and viruses, bacteria and environment. Vet. Rec. 1996, 139, 308-313.
  • 6. Hirsh D. C., Jang S. S.: Antimicrobial susceptibility of bacterial pathogens from horses. Vet. Clinic of North Am. Equine Pract. 1987, 3, 181-190.
  • 7. Hoffman A. M., Viel L., Prescott J. F.: Microbiologic changes during antimicrobial treatment and rate of relapse of distal respiratory tract infections in foals. Am. J. Vet. Res. 1993, 54, 1608-1614.
  • 8. Kester R. M., Lesser S.: Bacteria isolated from equine respiratory cultures. Eq. Pract. 1993, 15, 33-36.
  • 9. Kollias-Baker C., Johnson B.: A review of postmortem findings in cases of pneumonia in California racehorses. AAEP Proceedings 1999, 45, 319-321.
  • 10. Markiewicz Z., Kwiatkowski Z. A.: Bakterie, antybiotyki, lekooporność. PWN, Warszawa 2001.
  • 11. Papich M. G.: Antimicrobial therapy for horses, [w:] Current Therapy in Equine Medicine 5. Elsevier Science, Philadelphia 2003, 6-11.
  • 12. Pejsak., Jabłoński A., Żmudzki J.: Lekowrażliwość bakterii chorobotwórczych układu oddechowego świń. Medycyna Wet. 2005, 61, 664-668.
  • 13. Podschun R., Ullmann U.: Klebsiella spp. as nosocomial pathogens: epidemiology, taxonomy, typing methods and pathogenicity factors. Clin. Microbiol. Rev. 1998, 11, 589-603.
  • 14. Prescott J. F., Baggot J. D.: Antimicrobial therapy in veterinary medicine. Blackwell Science, Boston 1988.
  • 15. Raclyeft D. J., Love D. N.: Bacterial infection of the lower respiratory tract in 34 horses. Aust. Vet. J. 2000, 78, 549-559.
  • 16. Rush B., Mair T.: Equine Respiratory Diseases. Blackwell Science, Oxford 2004.
  • 17. Spurlock S. L.: Antimicrobial use in equine respiratory disease. Equine Pract. 1989, 11, 6-12.
  • 18. Stankiewicz M. M.: Mechanizmy oporności bakterii na antybiotyki i chemioterapeutyki, [w:] Problemy zdrowia narządu oddechowego młodych zwierząt gospodarskich. Rozpoznawanie i zapobieganie nieinfekcyjnym i infekcyjnym przyczynom zachorowań. Zakład Prewencji i Immunologii Weterynaryjnej, Wrocław 2002, 151-156.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

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