Galectin-1 expression in innervated and denervated skeletal muscle

• Autorzy: Svensson A , Tagerud S.
• Języki publikacji: EN

Abstrakty

EN

Galectin-1 is a soluble carbohydrate-binding protein with a particularly high expression in skeletal muscle. Galectin-1 has been implicated in skeletal muscle development and in adult muscle regeneration, but also in the degeneration of neuronal processes and/or in peripheral nerve regeneration. Exogenously supplied oxidized galectin-1, which lacks carbohydrate-binding properties, has been shown to promote neurite outgrowth after sciatic nerve sectioning. In this study, we compared the expression of galectin-1 mRNA and immunoreactivity in innervated and denervated mouse and rat hind-limb and hemidiaphragm muscles. The results show that galectin-1 mRNA expression and immunoreactivity are up-regulated following denervation. The galectin-1 mRNA is expressed in the extrasynaptic and perisynaptic regions of the muscle, and its immunoreactivity can be detected in both regions by Western blot analysis. The results are compatible with a role for galectin-1 in facilitating reinnervation of denervated skeletal muscle.

Słowa kluczowe

EN

galectin-1; protein expression; denervation; skeletal muscle; reinnervation

• Wydawca: -
• Czasopismo: Cellular and Molecular Biology Letters
• Rocznik: 2009
• Tom: 14
• Numer: 1
• Opis fizyczny: p.128-138,fig.,ref.

Twórcy

autor

Svensson A

• Uniersity of Kalmar, SE-391 82 Kalmar, Sweden

autor

Tagerud S.

Bibliografia

• 1. Barondes, S.H., Cooper, D.N., Gitt, M.A. and Leffler, H. Galectins. Structure and function of a large family of animal lectins. J. Biol. Chem. 269 (1994) 20807-20810.
• 2. Hsu, D.K. and Liu, F-T. Regulation of cellular homeostasis by galectins. Glycoconj. J. 19 (2004) 507-515.
• 3. Cooper, D.N. and Barondes, S.H. Evidence for export of a muscle lectin from cytosol to extracellular matrix and for a novel secretory mechanism. J. Cell. Biol. 110 (1990) 1681-1691.
• 4. Cooper, D.N., Massa, S.M. and Barondes, S.H. Endogenous muscle lectin inhibits myoblast adhesion to laminin. J. Cell. Biol. 115 (1991) 1437-1448.
• 5. Georgiadis, V., Stewart, H.J., Pollard, H.J., Tavsanoglu, Y., Prasad, R., Horwood, J., Deltour, L., Goldring, K., Poirier, F. and Lawrence-Watt, D.J. Lack of galectin-1 results in defects in myoblast fusion and muscle regeneration. Dev. Dyn. 236 (2007) 1014-1024.
• 6. Watt, D.J., Jones, G.E. and Goldring, K. The involvement of galectin-1 in skeletal muscle determination, differentiation and regeneration. Glycoconj. J. 19 (2004) 615-619.
• 7. McGraw, J., McPhail, L.T., Oschipok, L.W., Horie, H., Poirier, F., Steeves, J.D., Ramer, M.S. and Tetzlaff, W. Galectin-1 in regenerating motoneurons. Eur. J. Neurosci. 20 (2004) 2872-2880.
• 8. Plachta, N., Annaheim, C., Bissière, S., Lin, S., Rüegg, M., Hoving, S., Müller, D., Poirier, F., Bibel, M. and Barde, Y-A. Identification of a lectin causing the degeneration of neuronal processes using engineered embryonic stem cells. Nat. Neurosci. 10 (2007) 712-719.
• 9. Akazawa, C., Nakamura, Y., Sango, K., Horie, H. and Kohsaka, S. Distribution of the galectin-1 mRNA in the rat nervous system: its transient upregulation in rat facial motor neurons after facial nerve axotomy. Neurosci. 125 (2004) 171-178.
• 10. Whitney, P.L., Powell, J.T. and Sanford, G.L. Oxidation and chemical modification of lung β-galactoside-specific lectin. Biochem. J. 238 (1986) 683-689.
• 11. Horie, H., Inagaki, Y., Sohma, Y., Nozawa, R., Okawa, K., Hasegawa, M., Muramatsu, N., Kawano, H., Horie, M., Koyama, H., Sakai, I., Takeshita, K., Kowada, Y., Takano, M. and Kadoya, T. Galectin-1 regulates initial axonal growth in peripheral nerves after axotomy. J. Neurosci. 19 (1999) 9964-9974.
• 12. Horie, H., Kadoya, T., Hikawa, N., Sango, K., Inoue, H., Takeshita, K., Asawa, R., Hiroi, T., Sato, M., Yoshioka, T. and Ishikawa, Y. Oxidized galectin-1 stimulates macrophages to promote axonal regeneration in peripheral nerves after axotomy. J. Neurosci. 24 (2004) 1873-1880.
• 13. Magnusson, C., Högklint, L., Libelius, R. and Tågerud, S. Expression of mRNA for plasminogen activators and protease nexin-1 in innervated and denervated mouse skeletal muscle. J. Neurosci. Res. 66 (2001) 457-463.
• 14. Wilson, T.J., Firth, M.N., Powell, J.T. and Harrison, F.L. The sequence of the mouse 14 kDa β-galactoside-binding lectin and evidence for its synthesis on free cytoplasmic ribosomes. Biochem. J. 261 (1989) 847-852.
• 15. Magnusson, C., Libelius, R. and Tågerud, S. Nogo (reticulon 4) expression in innervated and denervated mouse skeletal muscle. Mol. Cell. Neurosci. 22 (2003) 298-307.
• 16. Svensson, A., Libelius, R. and Tågerud, S. Semaphorin 6C expression in innervated and denervated skeletal muscle. J. Mol. Histol. 39 (2008) 5-13.
• 17. Raz, A., Carmi, P. and Pazerini, G. Expression of two different endogenous galactoside-binding lectins sharing sequence homology. Cancer Res. 48 (1988) 645-649.
• 18. Raz, A., Meromsky, L. and Lotan, R. Differential expression of endogenous lectins on the surface of nontumorigenic, tumorigenic, and metastatic cells. Cancer Res. 46 (1986) 3667-3672.
• 19. Batt, J., Bain, J., Goncalves, J., Michalski, B., Plant, P., Fahnestock, M. and Woodgett, J. Differential gene expression profiling of short and long term denervated muscle. FASEB J. 20 (2006) 115-117.
• 20. Gajendran, N., Frey, J.R., Lefkovits, I., Kuhn, L., Fountoulakis, M., Krapfenbauer, K. and Brenner, H.R. Proteomic analysis of secreted muscle components: Search for factors involved in neuromuscular synapse formation. Proteomics 2 (2002) 1601-1615.
• 21. Gonzalez de Aguilar, J-L., Niederhauser-Wiederkehr, C., Halter, B., De Tapia, M., Di Scala, F., Demougin, P., Dupuis, L., Primig, M., Meininger, V. and Loeffler, J-P. Gene profiling of skeletal muscle in an amyotrophic lateral sclerosis mouse model. Physiol. Genomics 32 (2008) 207-218.
• 22. Chan, J., O´Donoghue, K., Gavina, M., Torrente, Y., Kennea, N., Mehmet, H., Stewart, H., Watt, D.J., Morgan, J.E. and Fisk, N.M. Galectin-1 induces skeletal muscle differentiation in human fetal mesenchymal stem cells and increases muscle regeneration. Stem Cells 24 (2006) 1879-1891.
• 23. Sola, O.M. and Martin, A.W. Denervation hypertrophy and atrophy of the hemidiaphragm of the rat. Am. J. Physiol. 172 (1953) 324-332.
• 24. Feng, T-P. and Lu, D-X. New lights on the phenomenon of transient hypertrophy in the denervated hemidiaphragm of the rat. Sci. Sin. 14 (1965) 1772-1784.
• 25. Gutmann, E., Haníková, M., Hájek, I., Klicpera, M. and Syrovy, I. The postdenervation hypertrophy of the diaphragm. Physiol. Bohemoslov. 15 (1966) 508-524.
• 26. Zhan, W-Z. and Sieck, G.C. Adaptations of diaphragm and medial gastrocnemius muscles to inactivity. J. Appl. Physiol. 72 (1992) 1445-1453.
• 27. Zhan, W-Z., Farkas, G.A., Schroeder, M.A., Gosselin, L.E. and Sieck, G.C. Regional adaptations of rabbit diaphragm muscle fibers to unilateral denervation. J. Appl. Physiol. 79 (1995) 941-950.
• 28. Rowley, K.L., Mantilla, C.B. and Sieck, G.C. Respiratory muscle plasticity. Respir. Physiol. Neurobiol. 147 (2005) 235-251.
• 29. Chang-Hong, R., Wada, M., Koyama, S., Kimura, H., Arawaka, S., Kawanami, T., Kurita, K., Kadoya, T., Aoki, M., Itoyama, Y. and Kato, T. Neuroprotective effect of oxidized galectin-1 in a transgenic mouse model of amyotrophic lateral sclerosis. Exp. Neurol. 194 (2005) 203-211.
• 30. Cho, M. and Cummings, R.D. Galectin-1, a β-galactoside-binding lectin in chinese hamster ovary cells. J. Biol. Chem. 270 (1995) 5198-5206.
• 31. Adams, L., Scott, G.K. and Weinberg, C.S. Biphasic modulation of cell growth by recombinant human galectin-1. Biochim. Biophys. Acta 1312 (1996) 137-144.
• 32. Vas, V., Fajka-Boja, R., Ion, G., Dudics, V., Monostori, É. and Uher, F. Biphasic effect of recombinant galectin-1 on the growth and death of early hematopoietic cells. Stem Cells 23 (2005) 279-287.
• 33. Miura, T., Takahashi, M., Horie, H., Kurushima, H., Tsuchimoto, D., Sakumi, K. and Nakabeppu, Y. Galectin-1β, a natural monomeric form of galectin-1 lacking its six amino-terminal residues promotes axonal regeneration but not cell death. Cell Death Differ. 11 (2004) 1076-1083.
• 34. Hsieh, S.H., Ying, N.W., Wu, M.H., Chiang C.L., Hsu, C.L., Wong, T.Y., Jin, Y.T., Hong, T.M. and Chen, Y.L. Galectin-1, a novel ligand of neuropilin-1, activates VEGFR-2 signaling and modulates the migration of vascular endothelial cells. Oncogene 27 (2008) 3746-3753.
• 35. Pellet-Many, C., Frankel, P., Jia, H. and Zachary, I. Neuropilins: structure, function and role in disease. Biochem. J. 411 (2008) 211-226.
• 36. Moret, F., Renaudot, C., Bozon, M. and Castellani, V. Semaphorin and neuropilin co-expression in motoneurons sets axon sensitivity to environmental semaphorin sources during motor axon pathfinding. Development 134 (2007) 4491-4501.
• 37. Lambrechts, D. and Carmeliet, P. VEGF at the neurovascular interface: Therapeutic implications for motor neuron disease. Biochim. Biophys. Acta 1762 (2006) 1109-1121.