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1997 | 44 | 3 |

Tytuł artykułu

The determination of thymopoietin conformation based on X-ray structure of a discontinuous thymopoietin-like motif of G-actin

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
The biologically active conformation of thymopoietin, based on X-ray data reported for discontinuous thymopoietin-like motif of G-actin, is proposed. The conformation is compared with that resulting from the prediction made by the method of Chou & Fasman (Annu. Rev. Biochem. 47, 251-276, 1978) and Rost & Sander (Methods Enzymol. 266, 525-539, 1996).

Wydawca

-

Rocznik

Tom

44

Numer

3

Opis fizyczny

p.519-525,fig.

Twórcy

  • University of Wroclaw, F.Joliot-Curie 14, 50-383 Wroclaw, Poland
autor
autor

Bibliografia

  • 1. Goldstein, G. (1974) Isolation of bovine thymin: A polypeptide hormone of thymus. Nature 247, 11-14.
  • 2. Barch, R.S. & Goldstein, G. (1974) Induction of T cell differentiation in vitro by thymin, a purified polypeptide hormon of the thymus. Proc. Natl. Acad. Sei. U.S.A. 71, 1474-1478.
  • 3. Goldstein, G., Audhya, T. & Heavner, G.A. (1981) Thymopoietins: Structural studies of these immunoregulatory polypeptides; in Peptides, Synthesis-Structure-Function, Proc. th Amer. Pept. Symp., Pierce, Rock ford, pp. 535-539.
  • 4. Siemion, I.Z., Słoń, J. & Wieczorek, Z. (1995) The immunosuppressive mini-domain of human lactoferrin. J. Peptide Sci. 1, 295-302.
  • 5. Szewczuk, Z., Siemion, I.Z. & Wieczorek, Z. (1996) Immunological properties of the thymopentin-like fragments of HLA-DQ. Molec. Immunol. 33. 903-908.
  • 6. Wieczorek, Z., Słoń, J., Kluczyk, A., Zbozień, R., Stefanowicz, P. & Siemion, I.Z. (1995) The immunomodulatory diversity of the proteins of transforming growth factor p (TGF p) fam­ily. Int. J. Peptide Protein Res. 46. 113-118.
  • 7. Goldstein, G. & Schlesinger, D.H. (1975) Thy­mopoietin and myasthenia gravis: Neostig- mine-responsive neuromuscular block pro- dued in mice by a synthetic peptide fragment of thymopoietin. Lancet 256-259.
  • 8. Kabsch, W. & Vandekerckove, J. (1992) Struc­ture and function of actin. Annu. Rev. Bio- phys. Biomol. Struct. 21, 49-76.
  • 9. Kabsh, W., Mannherz, H.G., Suck, D., Pai, E.F. & Holmes, K.C. (1990) Atomic structure of the actin:DNase I complex. Nature 347, 37-44.
  • 10. Rost, B. & Sander, C. (1993) Prediction of protein secondary structure at better than 70% accuracy. J. Mol. Biol. 232. 584-599.
  • 11. Rost, B. & Sander, C. (1994) Conservation and prediction of solvent accessibility in protein families. Proteins 20, 216-226.
  • 12. Rost, B. & Sander, C. (1996) Predicting one- dimentional protein structure by profile based neural networks. Methods. Enzymol. 266, 525-539.
  • 13. Chou, P.Y & Fasman, G.D. (1978) Empirical predictions of protein conformation. Annu. Rev. Biochem. 47, 251-276.

Typ dokumentu

Bibliografia

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bwmeta1.element.agro-article-3d12f047-ac8e-44d8-b621-c49bc55e053d
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