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2005 | 12 | 2 |

Tytuł artykułu

Co-existance of toxoplasmosis and neuroborreliosis - a case report

Treść / Zawartość

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
The 53-year-old woman was initially diagnosed with multiple sclerosis, despite the fact that she did not really meet the clinical criteria. Her only symptoms were clumsiness and weakness of the right extremities. Being a veterinary research worker she had been exposed to infectious material. In 1995, she was diagnosed with ELISA as having toxoplasmosis and treated as such. In 2002, after the infectious, flu-like disease, she revealed arthritis and drowsiness, also with memory and language impairment. The patient continued to have symptoms consistent with previously examined clumsiness. She was diagnosed with Lyme via ELISA and PCR, and treated. She made a full recovery from acute symptoms. After a few months, neurological and neuropsychological examinations were performed. On the background of mild cognitive decline apraxia and difficulties of attention were noted as the main problems. A apraxia of the right hand complicated the patient's life and depreciated her quality of life. The patient underwent MRI examination. FSE, FAST and FLAIR sequences were made. The MRI demonstrated the appearance of several small hyperintense lesions in the white matter of the left and right frontal and left parietal lobe. These lesions were typical of the post-inflammatory leucoencephalopathy. Additionally, a ring-shaped, low-intensity lesion in the posterior part of the left parietal lobe was noticed. The lesion was 8 mm in diameter and described to be an old toxoplasmosis lesion. The patient had been treated and the symptoms consistent with Lyme disease resolved. Patient continues to have symptoms consistent with focal destruction of the parietal lobe. Over the past six months, she has not progressed and relapsed in a manner that is consistent with MS.

Wydawca

-

Rocznik

Tom

12

Numer

2

Opis fizyczny

p.305-308,fig.,ref.

Twórcy

autor
  • Institute of Agricultural Medicine, Jaczewskiego 2, 20-090 Lublin, Poland
autor
autor

Bibliografia

  • 1. Adams WV, Rose CD, Eppes SC, Klein JD: Long-term cognitive effects of Lyme disease in children. Appl Neuropsychol 1999, 6(1), 39-45.
  • 2. Arendt G, Hefter H, Figge C, Neuen-Jakob E, Nelles HW, Elsing C, Freund HJ: Two cases of cerebral toxoplasmosis in AIDS patients mimicking HIV-related dementia. J Neurol 1991, 238(8), 439-442.
  • 3. Freidel S, Martin-Solch CH, Schreiter-Gasser U: Alzheimer’s dementia or cerebral toxoplasmosis? Case study of dementia following toxoplasmosis infection. Nervenarzt 2002, 73(9), 874-878 (German).
  • 4. Felgenhauer KH, Schadlich HJ, Nekic M, Ackermann R: Cerebrospinal fluid virus antibodies, a diagnostic indicator for multiple sclerosis? J Neurol Sci 1985, 71, 29-31.
  • 5. Halperin JJ: Nervous system Lyme disease. J Neurol Sci 1998, 153(2), 182-191.
  • 6. Lublin FD, Reingold SC.The National Multiple Sclerosis Society (USA) advisory Committee on Clinical Trials of New Agents in Multiple Sclerosis. Defining the clinical course of multiple sclerosis: results of an international survey. Neurology 1996, 46, 907-911.
  • 7. Noseworthy JH, Lucchinetti C, Rodriguez M, Weinshenker BG: Multiple sclerosis. N Eng J Med 2000, 343, 938-952.
  • 8. Poplawska R, Konarzewska B, Gudel-Trochimowicz I, Szulc A: Psychologic disorders in acute and persistent neuroborreliosis. Pol Merkuriusz Lek 2001, 10, 36-37.
  • 9. Poser S, Luer W, Eichenlaub D, Pohle HD, Weber T, Jurgens S, Felgenhauer K: Chronic HIV encephalitis-II. Clinical aspects. Klin Wochenschr 1988, 66(1), 26-33.
  • 10. Primavera A, Gazzola P, De Maria AF: Neuropsychological deficits in neuroborreliosis [letter]. Neurology 1999, 53(4), 895-896.
  • 11. Steere AC, Malawista SE, Hardin JA, Ruddy S, Askenase W, Andiman WA. Erythema chronicum migrans and Lyme arthritis. The enlarging clinical spectrum. Ann Intern Med 1977, 86(6), 685-698.
  • 12. Steere AC, Kalish RA, Kaplan RF, Taylor E, Logigian EL: Clinical Manifestation of Lyme disease chronic arthiritis and encephatopathy. In: Cevenini R, Sambri V, La Placa M (Eds): Advances in Lyme borreliosis research, VI International Conference on Lyme borreliosis, Bologna, Italy, June 19-22, 1994, 127-131. Societa Editrice Esculapio, Bologna, 1994.
  • 13. Steere AC, Schoen RT, Taylor E: The clinical evolution of Lyme arthritis. Ann Intern Med 1987, 107(5), 725-731.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

bwmeta1.element.agro-article-305e237c-c98e-4472-ac64-f44726e90938
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