Detecting a deletion in the coding region of the bovine bone morphogenetic protein 15 gene [BMP15]

• Autorzy: Zhang L-P , Gan Q-F , Zhang X-H , Li H-D , Hou G-Y , Li J-Y , Gao X , Ren H-Y , Chen J-B , Xu S-Z
• Języki publikacji: EN

Abstrakty

EN

The aim of this study was to detect polymorphism in the bovine bone morphogenetic protein 15 (BMP15) gene. On the basis of PCR-SSCP and DNA sequencing, a 4-bp deletion was identified in the coding region of the gene. Sequence analysis revealed that the deletion altered the reading frame and introduced a stop codon at position 264. Eight breeds (Luxi, Qinchuan, Nanyang, Jinnan, Bohai Black, Menggolian, Holstein, and Simmental) were genotyped by PCR-SSCP. No cows homozygous for this mutation were observed in these breeds. Heterozygous cows were detected in Luxi, Qinchuan, Nanyang, Jinnan and Bohai Black cattle. Fecundity was not increased in heterozygous individuals.

• Wydawca: -
• Czasopismo: Journal of Applied Genetics
• Rocznik: 2009
• Tom: 50
• Numer: 2
• Opis fizyczny: p.145-148,fig.,ref.

Twórcy

autor

Zhang L-P

• Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, P.R. China

autor

Gan Q-F

• College of Animal Science, Fujian Agricultural and Forestry University, Fuzhou, China

autor

Zhang X-H

• College of Animal Science and Technology, Henan University of Science & Technology, Luoyang, Henan, China

autor

Li H-D

• Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, P.R. China

autor

Hou G-Y

• Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, P.R. China

autor

Li J-Y

• Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, P.R. China

autor

Gao X

• Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, P.R. China

autor

Ren H-Y

• Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, P.R. China

autor

Chen J-B

• Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, P.R. China

autor

Xu S-Z

• Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, P.R. China

Bibliografia

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