Cystocyte and lymphocyte derived fusomes-spectrosomes: analogies and differences: a mini-review

• Autorzy: Dubielecka P M , Stebelska K. , Jazwiec B. , Sikorski A.F.
• Języki publikacji: EN

Abstrakty

EN

Structures analogous to Drosophila spectrosomes were found in mammalian lymphocytes. Repasky and colleagues discovered an intracellular spectrin-rich structure in lymphoid cells, which had far-reaching parallels with the fusome/spectrosome of D. melanogaster germ cells. This fact implies that spectrosomes may be characteristic not only of insect germ cells, but also that an analogous structure may play an important role in other cell types. The term “spectrosome” was first used by Lin and Spradling in 1995 to describe a large sphere of fusomal material in D. melanogaster germline stem cells and their differentiated daughter cells - cytoblasts. In the D. melanogaster ovary, membrane skeletal proteins such as ankyrin, α/β spectrin as well as adducin-like Hts protein(s) were found in this specific organelle - spectrosome/fusome. These organelles are involved in the creation of mitotic spindles and D. melanogaster cyst formation and oocyte differentiation, but the role of analogous spectrin based aggregates found in nucleated cells still remains unclear.

Słowa kluczowe

EN

spectrin; germ cell; fusome; membrane skeleton; lymphocyte; spectrosome; Drosophila; cystocyte; structural protein

• Wydawca: -
• Czasopismo: Cellular and Molecular Biology Letters
• Rocznik: 2003
• Tom: 08
• Numer: 1
• Opis fizyczny: p.221-229,fig.

Twórcy

autor

Dubielecka P M

• University of Wroclaw, Przybyszewskiego 63-77, 51-148 Wroclaw, Poland

autor

Stebelska K.

autor

Jazwiec B.

autor

Sikorski A.F.

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