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2007 | 63 | 08 |

Tytuł artykułu

Zmiany ilosciowe populacji limfocytow CD3 plus i CD45RA plus we krwi szczurow poddanych dzialaniu wolnozmiennego pola elektromagnetycznego

Warianty tytułu

EN
Quantitative changes in CD3 plus and CD45RA plus lymphocytes in the blood of rats exposed to an extremely low frequency magnetic field

Języki publikacji

PL

Abstrakty

EN
It was reported that an extremely low frequency (ELF) electromagnetic field causes biological effects in vitro and in vivo. The major functions of the immune system are to develop the concept of “self” and eliminate what is “non-self”. In our preliminary study we proved that an extremely low frequency (ELF) magnetic field increased IgG concentration in the serum of rats. The study was carried out on male Wistar rats. The rats were exposed during 3 or 6 days (8 minute a day) to an ELF magnetic field of a complex shape generated by a device used in medicine. Five groups were used in this experiment: Group I - control group, absence of ELF magnetic field, Group II - exposure during 3 days (B = 0.06 mT), Group III - exposure during 3 days (B = 0.14 mT), Group IV - exposure during 6 days (B = 0.06 mT), Group V - exposure during 6 days (B = 0.14 mT). The animals were sacrificed for the experiment on the 2nd day after exposure to the ELF magnetic field. The leukocytosis and lymphocytes subpopulations (CD3+ and CD45RA+) in the blood of rats were assayed. Our results did not show significant changes of leukocytosis in groups II, III and IV. In rats of group V the leukocytosis decreased. In all groups we observed a decrease of CD3+ lymphocytes during the experiment. ELF magnetic field (B = 0.14 mT) induced a decrease of CD45RA+ lymphocytes in rats of groups III and V.

Wydawca

-

Rocznik

Tom

63

Numer

08

Opis fizyczny

s.951-954,tab.,bibliogr.

Twórcy

autor
  • Slaska Akademia Medyczna, ul.Jordana 19, 41-808 Zabrze
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Bibliografia

  • 1.Antonopoulos A., Yang B., Stamm A., Heller W. D., Obe G.: Cytological effect of 50 Hz electromagnetic fields on human lymphocytes in vitro. Mutat. Res. 1995, 346, 151-157.
  • 2.Balcavage W. X., Alvager T., Swez J., Goff C. W., Fox M. T., Abdullyava S., King M. W.: A mechanism of action of extremely low frequency electromagnetic fields on biological system. Biochem. Biophys. Res. Commun. 1996, 222, 374-378.
  • 3.Beck B., Beck E., Polaniak R., Salwiczek A., Drzazga Z.: An effect of extremely low frequency magnetic field on alkaline phosphatase activity - in vivo and in vitro study. Phys. Med. 2004, 20, 31-33.
  • 4.Beck E., Beck B., Drzazga Z.: Influence of extremely low frequency magnetic field on alkaline phosphatase and gamma-glutamyl transpeptidase activity. Phys. Med. 2003, 19, 2, 105-109.
  • 5.Beck E., Beck B., Duliban H., Drzazga Z.: An effect of static and elf magnetic field on enzyme activity - in vitro study. IFMBE Proc., MEDICON 2001, Part II, 765-768.
  • 6.Beck B., Jędrzejowska-Szypułka H., Cholewka A., Król W, Drzazga Z.: An effect of extremely low frequency magnetic field on immunoglobulin G concentration in serum. Pol. J. Envir. Stud. 2005, 14, supl. II, 439-445.
  • 7.Boscolo P., Bergamaschi A., Di Sciascio M. B., Benvenuti F., Reale M., Di Stefano F., Conti P., Di Gioacchino M.: Effects of low frequency electromagnetic fields on expression of lymphocyte subsets and production of cytokines of men and women employed in a museum. Sci. Total Environ. 2001, 270, 13-20.
  • 8.Drzazga Z., Sieroń A., Liszka G., Wójcik J.: Pola magnetyczne stosowane w magnetoterapii. Baln. Pol. 1997, 39, 79-94.
  • 9.Goodman E. M., Greenbaum B., Marron M. T.: Effect of electromagnetic fields on molecules and cells. Int. Rev. Cytol. 1995, 158, 279-338.
  • 10.Goodman E. M.,Greenebaum B., Marron M. T.: Altered protein synthesis in cell-free system exposed to a sinusoidal magnetic field. Biochim. Biophys. Acta 1993, 1202, 107-112.
  • 11.Hauf R.: Hematological and biochemical effects of ELF fields in man-laboratory experiments, [w:] Grandolfo M., Michaelson S. M., Rindi A. (wyd.): Biological Effects and Dosimetry of Static and ELF Electromagnetic Fields. Plenum Press, New York-London 1985.
  • 12.Liboff A. R., Williams T., Strong D. M., Wistar R.: Time varying fields: Effects on DNA synthesis. Science 1984, 223, 818-820.
  • 13.Shimizu H., Suzuki Y., Okonogi H.: Biological effect of electromagnetic fields. Nippon Eiseigaku Zasshi 1995, 5, 919.
  • 14.Sieroń A., Cieślar G., Adamek M.: Magnetoterapia i Laseroterapia. Sląska Akademia Medyczna. Katowice 1994.
  • 15.Sieroń A., Cieślar G., Kamiński M., Teister M., Laitl-Kobierska A., Konieczny P.: Oddziaływanie zmiennego pola magnetycznego na aktywność wybranych enzymów błonowych i mitochondrialnych w hepatocytach u szczurów. Baln. Pol. 1997, 39, 3-4, 85-89.
  • 16.Sieroń A., Cieślar G., Kawczyk-Krupka A., Biniszkiewicz T., Bliska-Urban A., Adamek M.: Zastosowanie pól magnetycznych w medycynie. Ośrodek Wyd. "Augustana", Bielsko-Biała 2002.
  • 17.Tanaka T., Masuko T., Yagita H., Tamura T., Hashimoto Y.: Characterization of a CD3-like rat T cell surface antigen recognized by a monoclonal antibody. J Immunol. 1989, 142, 2791-2795.
  • 18.Tenforde T. S.: Biological interactions of extremely-low-frequency electric and magnetic fields. Bioelectrochem. Bioenerg. 1991, 25, 1-17.
  • 19.Woollett G. R., Barclay A. N., Puklavec M., Williams A. F.: Molecular and antigenic of the rat leukocyte-common antigen from thymocytes and T and B lymphocytes. Eur. J. Immunol. 1985, 15, 73-168.

Typ dokumentu

Bibliografia

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Identyfikator YADDA

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