EN
The influence of zinc on the activity of antioxidant enzymes in the blood of rats intoxicated with lead was studied. Exposure to lead at the concentration of 500 mg/dm3 for 6 weeks caused a decrease in the activities of SOD, GSH-PX and GR as well as an increase in MDA concentrations in the serum. Zinc at the concentration of 60 mg/dm3 administered for a period of 2 weeks after exposure to cadmium reduced the effects of toxic action of lead leading to a normalization of the activities of SOD and GR in the blood as well as MDA concentration in the serum.