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Tytuł artykułu

Mozliwosci uwalniania populacji swin od wirusa choroby Aujeszkyego przy pomocy programu "szczepienie - eliminacja"

Warianty tytułu

Języki publikacji

PL

Abstrakty

EN
The great progress achieved in recent years in molecular biology and genetic engineering disciplines enabled the creation of Aujeszky’s disease (AD) virus (SHV-1) deletion mutants, which establish a base for the elaboration of deletion (marker) vaccines. These vaccines together with appropriate serological tests (ELISA) enable the realization of a vaccination-eradication programme that gives real chances to eliminate SHV-1 from infected farms (regions, countries). The objective of the study was to introduce and evaluate the possibilities of SHV-1 elimination from pig populations in two highly infected pig farms in the Warmia and Masuria province in Poland. Pig vaccinations were done using deleted, gE- and TK- negative, live attenuated Nobi - Porvac Aujeszky Live Begonia vaccine (at present Porcilis Begonia) produced by Intervet Int., Holland. Reproductive pigs were vaccinated twice 4 weeks apart and then every 4 months at the same time. Replacement gilts were vaccinated twice before service and replacement boars twice in the quarantine period. Piglets born to vaccinated dams were vaccinated at 10-12 and 14-16 weeks of age. Observations of postvaccinal adverse effects and control of the epizootic situation in both herds were conducted. Clinical and epizootiological studies revealed neither local nor general adverse effects in pigs of various age groups. In spite of high SHV-1 infection levels no clinical signs of AD during vaccination - eradication programme in both herds were observed. This proved innocuity and good efficacy of Porcilis Begonia vaccine. The stages of implementing the vaccination-eradication programme in pig herds, as well as the necessity of a quick introduction of a complex AD eradication programme in Poland according to the general tendency in the EU were also presented in the paper.

Wydawca

-

Rocznik

Tom

56

Numer

03

Opis fizyczny

s.177-181,tab.,bibliogr.

Twórcy

autor
  • Uniwersytet Warminsko-Mazurski, ul. Oczapowskiego 13, 10-957 Olsztyn
autor
autor
autor
autor

Bibliografia

  • 1. Annelli J. F: Status of Aujeszky’s disease (Pseudorabies) in the Americas. Proc., O.I.E. Aujeszky’s Disease Symp., Bangkok, Thailand 1994, s. 71.
  • 2. De Leeuw P. W, Van Oirschot J. I: Vaccines against Aujeszky’s disease: evaluation of their efficacy under standardized laboratory conditions. Vet. Quart. 1985, 7, 191-197.
  • 3. De Smet К., De Waele К., Pensaert M, Goovaerts D., De Ridder Er. Field experiments to evaluate the feasibility of eradication of Aujeszky’s disease virus by different vaccination schedules. Vet. Quart. 1992, 14, 22-28.
  • 4. Janowski H„ Siemionek J., Szweda W.: Synteza badań nad epizootiologią i profilaktyką choroby Aujeszkyego w przemysłowym chowie trzody chlewnej, wykonywanych w latach 1981-85. Medycyna Wet. 1986, 42, 210-213.
  • 5.Kimman T. G., Oei-Lie N.. Van Zaane D.: Role of memory В-cell responses in serum and mucosal fluids of swine for protective immunity against pseudorabies virus. Am. J. Vet. Res. 1992, 53, 1992-1998.
  • 6. Lipowski A.: Znaczenie gospodarcze choroby Aujeszkyego. Medycyna Wet. 1992, 48, 339-341.
  • 7. McFerran J. В., Dow C„ McCracken R. M.: Experimental studies in weaned pigs with three vaccines against Aujeszky’s disease. Comp. Immun. Microbiol. Inf. Dis. 1979, 2, 327-334.
  • 8. McFerran J. B., McCracken R. M., Dow C.: Comparative studies with inactivated and attenuated vaccines for protection of fattening pigs. Curr. Top. Vet. Med. Anim. Sci. 1982, 17, 163-170.
  • 9. Nauwynck H. J., Pensaert M. B.: Programmes for the eradication of Aujeszky’s disease virus (pseudorabies virus) in the member states of the European Union. Proc., O.I.E. Aujeszky’s Disease Symp., Bangkok, Thailand 1994, s. 55.
  • 10.Pejsak Z:. Teoretyczne podstawy oraz praktyczne możliwości zwalczania choroby Aujeszkyego u świń. Medycyna Wet. 1990, 46, 129-133.
  • 11 .Pensaert M. B., De Smet К., De Waele K.: Extent and duration of virulent virus excretion upon challenge of pigs vaccinated with different glycoprotein - deleted Aujeszky’s disease virus. Vet. Microbiol. 1990, 22, 107-117.
  • 12.Pensaert Mr. Elimination - eradication of Aujeszky’s disease virus in Western - Europe: some considerations on the state of affairs. Proc., 3rd Int. Symp. „Aujeszky’s disease”, Ploufragan, France 1999, s. 367.
  • 13.Quint W, Gielkens A. L. J., Van Oirschot J. T, Berns A. J. M„ CuypersH. T: Construction and characterization of deletion mutants of pseudorabies virus: a new generation of „live” vaccines. J. Gen. Virol. 1987, 68, 523-534.
  • 14.Stegeman J. A.: Pseudorabies virus eradication by area-wide vaccination is feasible. Praca dokt., Faculteit Diergeneeskunde, Universiteit Utrecht, 1995. 15.Szweda W.. Koncicki A., Myszka J., Gajęcki M, Bączek W.: Rola zakażeń bezobjawowych w epizootiologii choroby Aujeszkyego w świetle badań własnych. Medycyna Wet. 1980, 36, 391-393.
  • 16.Szweda W., Janowski H.: Badania nad okresem utrzymywania się szczepów terenowych wirusa choroby Aujeszkyego (chA) w stadach świń swoiście szczepionych. Medycyna Wet. 1983, 39, 163-167.
  • 17.Szweda W, Janowski H„ Grzechnik R.: Ocena przydatności badań serologicznych w zapobieganiu chorobie Aujeszkyego przy kompletowaniu stad podstawowych w nowo tworzonych fermach świń. Mat. VIII Kongresu PTNW, Warszawa 1987, s. 179.
  • 18.Szweda W: Badania nad zastosowaniem różnych metod zapobiegania i zwalczania choroby Aujeszkyego u trzody chlewnej. Praca hab., Wydz. Medycyny Weterynaryjnej, ART Olsztyn, 1992.
  • 19.Szweda W, Grzechnik R., Bronicka A.: Rozprzestrzenienie wirusa choroby Aujeszkyego w populacji świń w województwie olsztyńskim. Weterynaria, Olsztyn 1995, 22, 77-85.
  • 20. Thawley D. G., Gustafson D. R, Beran G. W.: Pseudorabies for the elimination of pseudorabies virus from herds of swine. J. Am. Vet. Med. Ass. 1982, 181, 1513-1518.
  • 21. Van Oirschot J. T, Rziha H. J., Moonen P. J. L. My Pol J. M. A., Van Zaane D.: Differentiation of serum antibodies from pigs vaccinated or infected with Aujeszky’s disease virus by a competitive enzyme immunoassay. J. Gen. Virol. 1986, 67, 1179-1182.
  • 22. Van Oirschot J. T, Gielkens A. L. J.: Vaccines against Aujeszky’s disease: comparison of efficacy, DNA fingerprints and antibody response to glycoprotein I. Vet. Quart. 1987, 9, 37-49.
  • 23. Van Oirschot J. T.: The antibody response to glycoprotein I and the control of Aujeszky’s disease. Curr. Top. Vet. Med. Anim. Sci. 1989, 49, 129-133.
  • 24. Van Oirschot J. T, Oei H. L. : Comparison of two ELISAs for detecting antibodies to glycoprotein I of Aujeszky’s disease virus. Vet. Rec. 1989, 125,63- -64.
  • 25. Van Oirschot J. T, Gielkens A. L. J., Moormann R. J. M., Berns A. J. M. Marker vaccines, virus protein - specific antibody assays and the control of Aujeszky’s disease. Vet. Microbiol. 1990, 23, 85-101.
  • 26. Van Oirschot J. T, Wijsmuller J. M, De Waal С. A. H., Van Lith P. M: A novel concept for the control of Aujeszky's disease: Experiences in two vaccinated pig herds. Vet. Rec. 1990, 126, 159-163.
  • 27. Van Oirschot J. T: Why Pseudorabies is a candidate for eradication. Proc., 1 st. Int. Symp. „The Eradication of Pseudorabies (Aujeszky’s) Virus”, St. Paul, Minnesota, USA 1991, s. 85.
  • 28. Visser N., Ltitticken D.: Experiences with a gU/ТКг modified live pseudorabies virus vaccine: strain Begonia. Curr. Top. Vet. Med. Anim. Sci. 1988,49, 37-44.
  • 29. Wittmann G.: Aujeszky’s disease: factors important for epizootiology and control. Proc., 11th Conf. O.I.E. Reg. Comm. Eur., Vienna, Austria 1984, s. 3.
  • 30. Wittmann G., Rziha H. J.: Aujeszky’s disease (Pseudorabies) in pigs, w: Herpesvirus diseases of cattle, horses and pigs, red. G. Wittmann, Kluwer Acad. Publ., Boston 1989, s. 230.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

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