Dactinomycin-induced veno-occlusive disease in rats. The hepatoprotective action of amifostine. Evaluation in a light and electron microscope

• Autorzy: Borowska H , Arciszewska E. , Czauderna P. , Sawicki B.
• Języki publikacji: EN

Abstrakty

EN

The purpose of the study was to draw upan experimental model of hepatic veno-occlusive disease (VOD) induced by dactinomycin (ACT) and to investigate the possible hepatoprotective effects of Ethyol (amifostine). Pathological changes corresponding to a VOD picture of varying intensification were found in the liver samples obtained from all the rats receiving ACT. Amifostine appears to act protectively to liver changes caused by dactinomycin.

Słowa kluczowe

EN

amifostine; chemotherapy; ethyol; pathological change; veno-occlusive disease; liver; dactinomycin; liver change

• Wydawca: -
• Czasopismo: Folia Morphologica
• Rocznik: 2004
• Tom: 63
• Numer: 1
• Opis fizyczny: p.91-93,fig.,ref.

Twórcy

autor

Borowska H

• Medical University, Kilinskiego 1, 15-089 Bialystok, Poland

autor

Arciszewska E.

autor

Czauderna P.

autor

Sawicki B.

Bibliografia

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