Zaleznosc miedzy polimorfizmem w genie leptyny a liczba komorek somatycznych i cechami uzytkowosci mlecznej krow

• Autorzy: Kulig H , Kmiec M. , Kowalewska-Luczak I. , Wojdak-Maksymiec K. , Torchala-Bielaszewska K.

Warianty tytułu

EN

Association between leptin gene polymorphism, somatic cell count, and milk production traits in cows

• Języki publikacji: PL

Abstrakty

EN

The aim of the study was to investigate how leptin R4C single nucleotide polymorphism (SNP) in the leptin gene affects the somatic cell count (SCC) in milk as well as milk production traits such as daily milk yield, fat content, protein content, lactose content, and dry matter content in milk. A total of 162 Polish Holstein- -Friesian (Red-White strain) cows were used in this study. The genotype and allele frequencies were as follows: CC - 0.26, CT - 0.56, TT - 0.18, C - 0.54, T - 0.46. Statistical analysis revealed that the studied polymorphism significantly affected the daily milk yield (P ≤ 0.05). The results indicate that selection of R4C TT animals might contribute to increased milk yield in Holstein-Friesian cattle.

Słowa kluczowe

PL

genetyka zwierzat; hodowla zwierzat; bydlo; krowy mleczne; leptyna; gen leptyny; polimorfizm genetyczny; cechy uzytkowosci mlecznej; wydajnosc mleka; wydajnosc dobowa; mleko; zawartosc tluszczu; zawartosc bialka; zawartosc laktozy; liczba komorek somatycznych

• Wydawca: -
• Czasopismo: Medycyna Weterynaryjna
• Rocznik: 2008
• Tom: 64
• Numer: 07
• Opis fizyczny: s.915-917,tab.,bibliogr.

Twórcy

autor

Kulig H

• Akademia Rolnicza w Szczecinie, ul.Doktora Judyma 6, 71-466 Szczecin

autor

Kmiec M.

autor

Kowalewska-Luczak I.

autor

Wojdak-Maksymiec K.

autor

Torchala-Bielaszewska K.

Bibliografia

• 1. Bernotiene E., Palmer G., Gabay C.: The role of leptin in innate and adaptive immune responses. Arthritis Res. Ther. 2006, 8, 217-226.
• 2. Bonnet M., Delavaud C., Laud K., Gourdou I., Leroux C., Djiane J., Chilliard Y.: Mammary leptin synthesis, milk leptin and their putative physiological roles. Reprod. Nutr. Dev. 2002, 42, 399-413.
• 3. Bruno A., Conus S., Schmid I., Simon H.-U.: Apoptotic pathways are inhibited by leptin receptor activation in neutrophils. J. Immunol. 2005, 174, 8090-8096.
• 4. Buchanan F. C., Fitzsimmons C. J., Van Kessel A. G., Thue T. D., Winkelman-Sim D. C., Schmutz S. M.: Association of a missense mutation in the bovine leptin gene with carcass fat content and leptin mRNA levels. Genet. Sel. Evol. 2002, 34, 105-116.
• 5. Buchanan F. C., Van Kessel A. G., Waldner C., Christensen D. A., Laarveld B., Schmutz S. M.: Hot Topic: An association between a leptin single nucleotide polymorphism and milk and protein yield. J. Dairy Sci. 2003, 86, 3164-3166.
• 6. Houseknecht K. L., Baile C. A., Matteri R. L., Spurlock M. E.: The Biology of leptin: a review. J. Anim. Sci. 1998, 76, 1405-1420.
• 7. Komisarek J., Szyda J., Michalak A., Dorynek Z.: Impact of leptin gene polymorphism on breeding value for milk production traits in cattle. J. Anim. Feed Sci. 2005, 14, 491-500.
• 8. Konfortov B. A., Licence V. E., Miller J. R.: Re-sequencing of DNA from a diverse panel of cattle reveals a high level of polymorphism in both intron and exon. Mamm. Genome 1999, 10, 1142-1145.
• 9. Kulig H.: Association between leptin gene polymorphism and some performance traits of cattle. J. Anim. Feed Sci. 2005, 14, 235-243.
• 10. Liefers S. C., te Pas M. F., Veerkamp R. F., van der Lende T.: Associations between leptin gene polymorphisms and production, live weight, energy balance, feed intake, and fertility in Holstein heifers. J. Dairy Sci. 2002, 85, 1633-1638.
• 11. Liefers S. C., Veerkamp R. F., te Pas M. F. W., Delavaud C., Chilliard Y., van der Lende T.: Leptin concentrations in relation to energy balance, milk yield, intake, live weight, and estrus in dairy cows. J. Dairy Sci. 2003, 86, 799-807.
• 12. Madeja Z., Adamowicz T., Chmurzyńska A., Jankowski T., Melonek J., Świtoński M., Strabel T.: Short communication: Effect of leptin gene polymorphisms on breeding value for milk production traits. J. Dairy. Sci. 2004, 87, 3925-3927.
• 13. Matarese G., Moschos S., Mantzoros C. S.: Leptin in immunology. J. Immunol. 2005, 173, 3137-3142.
• 14. Pomp D., Zou T., Clutter A. C., Barendse W.: Rapid communication: Mapping of leptin to bovine chromosome 4 by linkage analysis of a PCR-based polymorphism. J. Anim. Sci. 1997, 75, 427.
• 15. Sender G., Korwin-Kossakowska A., Gralak B.: Wpływ polimorfizmu genu BoLA-DRB3 na wystêpowanie mastitis u krów. Medycyna Wet. 2005, 61, 540-542.
• 16. Sender G., Korwin-Kossakowska A., Hameid K. G. A., Prusak B.: Ocena wpływu polimorfizmu wybranych genów na występowanie mastitis u krów. Medycyna Wet. 2006, 62, 563-565.
• 17. Statistica, wersja 7.1., 2006, StatSoft Polska.
• 18. Wu X.-L., MacNeil M. D., De S., Xiao Q.-J., Michal J. J., Gaskins C. T., Reeves J. J., Busboom J. R., Wright Jr. R. W., Jiang Z.: Evaluation of candidate gene effect for beef backfat via Bayesian model selection. Genetica 2005, 125, 103-113.
• 19. Zhang Y., Proenca R., Maffei M., Barone M., Leopold L., Friedman J. M.: Positional cloning of the mouse obese gene and its human homologue. Nature 1994, 372, 425-432.
• 20. Zwierzchowski L., Krzyżewski J., Strzałkowska N., Siadkowska E., Ryniewicz Z.: Effects of polymorphism of growth hormone (GH), Pit-1, and leptin (LEP) genes, cow's age, lactation stage and somatic cell count on milk yield and composition of Polish Black-and-White cows. Anim. Sci. Pap. Rep. 2002, 20, 213-227.